NEOADJUVANT TREATMENT OF HER2-POSITIVE BREAST CANCER


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Resumo

A number of international clinical trials involving Russian oncological centers have justified broad prospects for dual blockade of HER2-positive breast cancer as the metastatic process and during neoadjuvant therapy including anthracyclines and taxanes in combination with pertuzumab and trastuzumab. The antitumor activity of the Russian combined drug «pertuzumab+trastuzumab» (Beyodim) is confirmed by increase in relapse-free and overall survival.

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Sobre autores

V. Semiglazov

FSBI "SRI of Oncology n.a. N.N. Petrov" of RMPH

Email: vsemiglazov@mail.iu
MD, Prof., Honored Scientist, Corresponding Member of RAS, Head of the Scientific Department of Bieast Tumors, Chief Researcher St.-Petersburg

V. Semiglazov

St. Petersburg State Medical University n.a. Acad. I.P. Pavlov of RMPH

St.-Petersburg

G. Dashyan

FSBI "SRI of Oncology n.a. N.N. Petrov" of RMPH

St.-Petersburg

P. Krivorotko

FSBI "SRI of Oncology n.a. N.N. Petrov" of RMPH

St.-Petersburg

K. Nikolaev

FSBI "SRI of Oncology n.a. N.N. Petrov" of RMPH

St.-Petersburg

T. Semiglazova

FSBI "SRI of Oncology n.a. N.N. Petrov" of RMPH

St.-Petersburg

A. Komyakhov

St. Petersburg State Medical University n.a. Acad. I.P. Pavlov of RMPH

St.-Petersburg

A. Bessonov

FSBI "SRI of Oncology n.a. N.N. Petrov" of RMPH

St.-Petersburg

R. Donskikh

FSBI "SRI of Oncology n.a. N.N. Petrov" of RMPH

St.-Petersburg

R. Paltuev

FSBI "SRI of Oncology n.a. N.N. Petrov" of RMPH

St.-Petersburg

K. Zernov

FSBI "SRI of Oncology n.a. N.N. Petrov" of RMPH

St.-Petersburg

Bibliografia

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  7. U.S. Food and Drug Administration. FDA approves Perjeta for neoadjuvant breast cancer treatment. http://www. fda.gov/NewsEvents/ Newsroom/PressAnnouncements/ucm370393. htm. Accessed March 3, 2015.
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