ROXITHROMYCIN: PHARMACOLOGICAL PROPERTIES AND CLINICAL APPLICATION
- Autores: Zaitsev A.A1
-
Afiliações:
- FSBEI HE First MSMU n.a. I.M. Sechenov of RMH
- Edição: Nº 18 (2016)
- Páginas: 84-90
- Seção: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/289459
- ID: 289459
Citar
Texto integral
Acesso aberto
Acesso está concedido
Acesso é pago ou somente para assinantes
Resumo
The publication is devoted to the analysis of the use of a macrolide antibiotic roxithromycin in the treatment of respiratory tract infections. The pharmacological properties of the drug, the mechanism of action, and current data on resistance of respiratory pathogens to macrolides are presented. The results of clinical studies analyzing the effectiveness of Roxithromycin in the treatment of respiratory infections are discussed; directions of antimicrobial therapy of community-acquired pneumonia are considered. Special attention is paid to the issues of compliance with antimicrobial therapy.
Palavras-chave
Texto integral
Sobre autores
A. Zaitsev
FSBEI HE First MSMU n.a. I.M. Sechenov of RMHMD, Prof. at the Department of Hematology and Geriatrics
Bibliografia
- Ferech M., Coenen S., Malhotra-Kumar S., Dvorakova K., Flendrickx E., Suetens C., Goossens H. European Surveillance of Antimicrobial Consumption (ESAC): outpatient antibiotic use in Europe. J. Antimicrob. Chemother. 2006, 58(2):401-7.
- Klein J. History of macrolide use in pediatrics. Pediatr. Infect. Dis. 1997;4(16):427-34.
- Zara G., Qin X., Pilot M., et al. Response of the human gastrointestinal tract to erythromycin. J. Gastroin. Motil. 1991;3:26-31.
- Rangel-Frausto M., Pittet D., Costigan M., Hwang T., Davis C.S., Wenzel R.P. The natural history of the systemic inflammatory response syndrome (SIRS): a prospective study. JAMA. 1995;273:117-23.
- Страчунский Л.С., Козлов С.Н. Макролиды в современной клинической практике Доступно на: http://www.antibiotic.ru/books/macrolid/ intro.shtml
- Bryskier A., Bergogne-Berezin E. Macrolides. In: Antibacterial and antifungal Agents. Bryskier A, ed. ASM-Press (Washington DC), 2005.
- Roxithromycin: a new macrolides. Symposium. Paris, 29-30 may 1987. J. Antimicrob. Chemopther. 1987;20:1-187.
- Paulsen O. Roxithromycin - a macrolide with improved pharmacokinetic properties. Drugs Today. 1991;27:193-222.
- Bryskier A. Roxithromycin: review of its antimicrobial activity. J. Antimicrob. Chemother. 1998;41:1-21.
- Bryskier A., Omura S., ed. Macrolide antibiotics. 2nd ed. Academic Press, 2002.
Arquivos suplementares
