POTENTIALS FO CITRATE THERAPY IN THE TREATMENT OF PATIENTS WITH UROLITHIASIS


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Resumo

The article provides an overview of current approaches to treatment and prevention of urolithiasis. The basic methods of conservative management of patients with urolithiasis, including lithokinetic, litholytic and metaphylactic therapy, are considered. The mechanism of action of the citrate mixture on uric acid - the main component required for the formation of stones in the urinary tract - is described. Case reports with justified use of citrate mixture are presented, and main contraindications are discussed. Algorithm of urologist’s action for the purpose of diagnosis of urolithiasis and making decision on the possibility of use of citrate therapy is presented. It is noted that the preparation for citrate therapy is available in convenient dosage form that allows to achieve not only the pharmacological benefits, but also improve patient compliance.

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Sobre autores

L. Rapoport

SRI Uronephrology and Reproductive Health SBEI НРБ First MSMU n. a. I.M. Sechenov of RMPH; SBEI НРБ First MSMU n.a. I.M. Sechenov of RMPH

D. Tsarichenko

SBEI НРБ First MSMU n.a. I.M. Sechenov of RMPH

V. Saenko

SBEI НРБ First MSMU n.a. I.M. Sechenov of RMPH

E. Frolova

SRI Uronephrology and Reproductive Health SBEI НРБ First MSMU n. a. I.M. Sechenov of RMPH; University Clinical Hospital №2 SBEI НРБ First MSMU n.a. I.M. Sechenov of RMPH

Email: frolo-ekaterin@yandex.ru
Postgraduate student; Urologist at the Urological Department №3

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