Predicting the recurrence of basal cell carcinoma of the scalp

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Resumo

Objective: Identification of factors that provoke the recurrence of basal cell carcinoma of the scalp after previous treatment and development of the method for predicting local recurrence of basal cell carcinoma of the scalp.

Materials and methods: 100 patients were studied, including 50 patients with newly diagnosed basal cell carcinoma of the scalp and 50 patients with recurrent basal cell carcinoma of the scalp. To predict recurrence, binary logistic regression models with risk factors for basal cell carcinoma of the scalp were evaluated.

Results: Diagnostically significant criteria for basal cell carcinoma of the scalp recurrence were identified for tumor localization in the nasal skin area (p = 0.01), with a deep resection margin of less than 1 mm (p = 0.03), and patient age.

Conclusion: A formula for predicting basal cell carcinoma (BCC) recurrence has been developed.

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Sobre autores

Тatiana Ermakova

City Clinical Oncology Dispensary

Autor responsável pela correspondência
Email: ermakova.ts@mail.ru
ORCID ID: 0000-0002-1899-554X
Código SPIN: 6016-9163

Oncologist

Rússia, Saint Petersburg

Eldar Topuzov

City Clinical Oncology Dispensary; North-Western State Medical University named after I.I. Mechnikov

Email: eltop@inbox.ru
ORCID ID: 0000-0002-2105-2251
Código SPIN: 1065-4191

Dr. Sci. (Med.), Professor, Chief Physician; Head of Department of Surgery n. a. V.A. Oppel

Rússia, Saint Petersburg; Saint Petersburg

Svetlana Kutukova

City Clinical Oncology Dispensary; Pavlov First Saint Petersburg State Medical University

Email: dr.s.kutukova@gmail.com
ORCID ID: 0000-0003-2221-4088
Código SPIN: 6735-6556

Dr. Sci. (Med.), Professor, Department of Dentistry, Surgical and Maxillofacial Surgery; Associate Professor, Department of Oncology, Faculty of Postgraduate Education; Oncologist, Department of Antitumor Drug Therapy No. 10

Rússia, Saint Petersburg; Saint Petersburg

Vladimir Ershov

City Clinical Oncology Dispensary

Email: ershov415@gmail.com
ORCID ID: 0000-0002-8641-1489

Dr. Sci. (Med.), Head of Department of Cytology Laboratory

Rússia, Saint Petersburg

Bibliografia

  1. WHO Classification of Skin Tumours. WHO Classification of Tumours, 4th Edition. 2018;11.
  2. Каприн А.Д., Старинский В.В., Петрова Г.В. Злокачественные новообразования в России в 2018 году (заболеваемость и смертность). М., 2019. [Kaprin A.D., Starinsky V.V., Petrova G.V. Malignant neoplasms in Russia in 2018 (incidence and mortality). Moscow, 2019. (In Russ.)].
  3. Bichakjian C., Aasi S.Z., Alam M., et al: Basal cell skin cancer. NCCN clinical practice guidelines in oncology. Version 1.2019. August 31.2018. 2019:46.
  4. Кива Е.В., Дворников А.С., Пустынский И.Н. и др. Диффе-ренцированный подход к лечению больных с рецидивами базальноклеточного рака кожи головы. Хирург. 2019;12:43–53. [Kiva E.V., Dvornikov A.S., Pustynsky I.N., et al. Differentiated approach to the treatment of patients with recurrent basal cell carcinoma of the scalp. Surgeon. 2019;12:43–53. (In Russ.)]. https://dx.doi.org/10.33920/med-15-1912-04
  5. Самуленко А., Мордовский А., Поляков А. Современная стратегия лечения базальноклеточного рака кожи головы и шеи. Врач. 2017;12:5–8. [Samulenko A., Mordovsky A., Polyakov A. Modern strategy for the treatment of basal cell carcinoma of the scalp and neck. Vrach. 2017;12:5–8. (In Russ.)].
  6. Седаков И.Е., Логунов П.В., Дьячков О.Н. Опыт комбинированного лечения базальноклеточного рака кожи. Торсуевские чтения: научно-практический журнал по дерматологии, венерологии и косметологии. 2019;2(24):59–63. [Sedakov I.E., Logunov P.V., Dyachkov O.N. Experience with combined treatment of basal cell carcinoma of the skin. Torsuyevskiye chteniya: nauchno-prakticheskiy zhurnal po dermatologii, venerologii i kosmetologii. 2019;2(24):59–63. (In Russ.)].
  7. Тарасенко Г.Н., Коленько Н.Г., Тарасенко Ю.Г. Базальноклеточный рак кожи: современные клинико-диагностические особенности и роль ранней диагностики. Российский журнал кожных и венерических болезней. 2020;23(1):12–6. [Tarasenko GN, Kolenko NG, Tarasenko YuG. Basal cell carcinoma of the skin: current clinical and diagnostic features and the role of early diagnosis. Rossiyskiy zhurnal kozhnykh i venericheskikh bolezney=Russian Journal of Skin and Venereal Diseases. 2020;23(1):12–6. (In Russ.)]. https://dx.doi.org/10.17816/dv2020112-16
  8. Lee C.T., Lehrer E.J., Aphale A., et al. Surgical excision, Mohs micrographic surgery, external-beam radiotherapy, or brachytherapy for indolent skin cancer: An international meta-analysis of 58 studies with 21,000 patients. Cancer. 2019;125(20):3582–94. https://dx.doi.org/10.1002/cncr.32371
  9. Bozan A., Gode S., Kaya I., et al. Long-term Follow-up of Positive Surgical Margins in Basal Cell Carcinoma of the Face. Dermatol Surg. 2015;41(7):761–7. https://dx.doi.org/10.1097/DSS.0000000000000394
  10. Gulleth Y., Goldberg N., Silverman R.P., Gastman B.R. What is the best surgical margin for a Basal cell carcinoma: a meta-analysis of the literature. Plast Reconstr Surg. 2010;126(4):1222–31. https://dx.doi.org/10.1097/PRS.0b013e3181ea450d
  11. Wolf D.J., Zitelli J.A. Surgical margins for basal cell carcinoma. Arch Dermatol. 1987;123(3):340–4.
  12. Волгин В.Н., Кагоянц Р.В., Садыкова Р.Н., Мингазова Э.Н. К оценке эффективности методов лечения пациентов различных возрастных групп с базальноклеточным раком кожи носа и ушных раковин. Проблемы социальной гигиены, здравоохранения и истории медицины. 2024;32(Suppl. 1):562–6. [Volgin V.N., Kagoyants R.V., Sadykova R.N., Mingazova E.N. Assessing the effectiveness of treatment methods for patients of different age groups with basal cell carcinoma of the skin of the nose and ears. Problemy sotsial’noy gigiyeny, zdravookhraneniya i istorii meditsiny. 2024;32(Suppl. 1):562–6. (In Russ.)]. https://dx.doi.org/10.32687/0869-866X-2024-32-s1-562-566
  13. Ермоленко Е.А. Наиболее распространенная локализация и современные подходы в лечении различных форм базалиом. Студенческий. 2019;16–1(60):90–2. [Ermoolenko E.A. The most common localization and current approaches to the treatment of various forms of basaliomas. Studencheskiy. 2019;16–1(60):90–2. (In Russ.)].

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2. Figure 1. Comparison of patient groups with recurrent BCSC and primary BCSC by age

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3. Figure 2. Comparison of patient groups with recurrent BCSC and primary BCSC by BCSC location on the nose relative to other BCSC locations on the head

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4. Figure 3. ROC curve for the recurrence prediction model depending on age and tumor location in the nose

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5. Figure 4. Comparison of patient groups with recurrent BCSC and primary BCSC by deep margin resection depth of 1 mm or less

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