Современные подходы к лечению остеоартрита: роль инъекционных медленнодействующих симптом-модифицирующих препаратов


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Аннотация

В статье обсуждаются причины боли при остеоартрите (ОА), роль воспаления в патогенезе заболевания и ограничения применения нестероидных противовоспалительных средств (НПВС). Освещаются современные международные рекомендации 2014 и 2016 гг., в соответствии с которыми лечение ОА рекомендовано начинать с медленнодействующих симптом-модифицирующих препаратов (SYSADOA - Symptomatic Slow-Acting Drugs in Osteoarthritis). Приведены данные об анальгетическом и противовоспалительном действиях хондроитин сульфата (ХС), о его безопасности. Показано, что достичь более быстрого эффекта возможно при применении инъекционной формы ХС. Приведены данные о механизме действия, безопасности и эффективности препаратов гиалуроновой кислоты

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Об авторах

Н. В Чичасова

ФГАОУ ВО «Первый МГМУ им. И.М. Сеченова» Минздрава России (Сеченовский Университет)

Email: kafedrarheum@yandex.ru
д.м.н., проф. кафедры ревматологии

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