Биологические препараты в терапии воспалительных заболеваний кишечника: реальность и перспективы


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Аннотация

Этиология воспалительных заболеваний кишечника (ВЗК) неизвестна, а патогенез понятен не в полном объеме. На сегодняшний день для пациентов с ВЗК в Российской Федерации доступны моноклональные антитела к фактору некроза опухоли а и антитела против α4-β7. Но в настоящее время в мире активно развивается направление таргетной терапии: накапливается опыт применения первых препаратов, продолжается поиск новых молекул, способных прерывать воспалительный каскад и одновременно с этим имеющих высокий профиль безопасности.

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Об авторах

М. И Скалинская

ФГБОУ ВО СЗГМУ им. И.И. Мечникова

Email: mskalinskaya@yahoo.com
к.м.н., доцент кафедры пропедевтики внутренних болезней, гастроэнтерологии и диетологии

И. Г Бакулин

ФГБОУ ВО СЗГМУ им. И.И. Мечникова

Е. В Сказываева

ФГБОУ ВО СЗГМУ им. И.И. Мечникова

Т. Н Жигалова

ФГБОУ ВО СЗГМУ им. И.И. Мечникова

К. Н Рындин

ФГБОУ ВО СЗГМУ им. И.И. Мечникова

М. В Соловьев

ФГБВОУ ВО «Военно-медицинская академия им. С.М. Кирова» МО РФ

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