Мелоксикам - предпочтительный нестероидный противовоспалительный ингибитор циклооксигеназы-2


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Аннотация

Нестероидные противовоспалительные средства (НПВС) - наиболее широко распространенный способ лечения острых и хронических болевых синдромов. Однако их применение может сопровождаться развитием опасных осложнений в виде органических и функциональных нарушений сердечно-сосудистой системы и желудочно-кишечного тракта. В настоящее время в распоряжении врачей имеется широкий спектр НПВС, но ни один из представителей этой группы лекарственных препаратов не может считаться наилучшим. Наиболее приемлемым выбором для большинства больных в этой ситуации являются умеренно селективные НПВС, такие как мелоксикам. Этот препарат долго и широко используется в мировой клинической практике и завоевал доверие врачей и пациентов. Основные преимущества мелоксикама - доказанная эффективность, удобная схема применения, относительно низкий риск развития осложнений в виде органических и функциональных нарушений сердечнососудистой системы и желудочно-кишечного тракта, а также хорошая сочетаемость с низкими дозами ацетилсалициловой кислоты. Авторы работы провели исследование фармацевтической эквивалентности различных мелоксикамов, существующих на отечественном рынке, и получили интересные данные, представленные в настоящей статье.

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Об авторах

Е. Ю Плотникова

Кемеровский государственный медицинский университет

Email: eka-pl@rambler.ru
д.м.н., профессор кафедры поликлинической терапии, постдипломной подготовки врачей и ВСО, руков. курса клинической гастроэнтерологии 650022, Россия, Кемерово, ул. Ворошилова, 22а

М. Н Синькова

Кемеровский государственный медицинский университет

Кемерово, Россия

Л. К Исаков

Кемеровский государственный медицинский университет

Кемерово, Россия

А. С Сухих

Кемеровский государственный медицинский университет

Кемерово, Россия

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