Rannee naznachenie insulina glargin patsientam s sakharnym diabetom 2 tipa, prediabetom i vysokim serdechno-sosudistym riskom: rezul'taty issledovaniya ORIGIN


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The article analyzes the results of the ORIGIN study (Outcome Reduction with an Initial Glargine Intervention) study, which was aimed to evaluation of the effect of achieving fasting normoglycemia by early administration of insulin glargine in patients with dysglycemia compared with standard therapy. ORIGIN study added important new data demonstrating the potential benefits of therapy with insulin glargine at an earlier stage in the development of type 2 diabetes mellitus, and has once again highlighted the infinite potentials of insulin therapy, particularly using the modern insulin analogues. Currently, in consequence of ORIGIN study, insulin glargine (Lantus ®) is the most-studied insulin analogue in the treatment of diabetes mellitus.

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