Patogeneticheskiy podkhod k primeneniyu al'fa-lipoevoy kisloty v lechenii erektil'noy disfunktsii u patsientov s sakharnym diabetom


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The study was aimed to the assessment of the effectiveness of the alpha-lipoic acid at a dose of 600 mg per day in patients with diabetes mellitus (DM) type 2, erectile dysfunction (ED), disorders of libido, and other clinically significant symptoms of androgen deficiency. The study included 86 men with erectile dysfunction. The patient’s mean age was 51 year. Study group comprised 52 patients, control group included 34 patients. Evaluation of the effectiveness of the treatment was performed 12 weeks after administration of the drug. For the evaluation of the effectiveness of the therapy, validated questionnaires were used: the International Index of Erectile Function 5 (IIEF-5), and the Aging Male Simptoms (AMS) by Heinemann. The results of the study allow to recommend the alpha-lipoic acid as a pathogenic agent for the treatment of erectile dysfunction in patients with diabetes mellitus.

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