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编号 12 (2014)

Articles

Mify o kontratseptsii v sovremennoy Rossii

Podzolkova N., Erofeeva L., Safina E., Sumyatina L.

摘要

Given the current socio-economic and demographic development, reproductive health of the population is the primary challenge for the health care system. The concept of demographic development dictates the need to preserve the reproductive potential of the population. Therefore, the most important problem of reducing unwanted pregnancies and contraception include a lack of training obstetricians and gynecologists, and lack of a unified training system. The joint work was aimed to the evaluation of the opinions of physicians, obstetrician-gynecologists on reproductive health of women in the family planning and the formation of competence on the basis of knowledge, professional experience and skills. 232 obstetrician-gynecologist from 26 regions of the Russian Federation were surveyed. Analysis of the questionnaire data showed the presence of a large amount of passive information, combined with the lack of skills of self-critical reflection of current data, adherence to prevailing views, the lack of professional communication of practitioners and lack of knowledge of the unique World medical standard for regulating the use of contraceptives (WHO, 2009). It was concluded that formation of competence in the medical practice requires a modular approach.
Pharmateca. 2014;(12):8-11
pages 8-11 views

Trombofilicheskie riski sovremennoy gormonal'noy kontratseptsii

Pustotina O.

摘要

The article presents the literature data on the impact of modern hormonal contraceptives on thrombophilic risk; a comparative characterization of various synthetic gestogens and estrogens in relation to the development of arterial and venous thrombosis is presented.
Pharmateca. 2014;(12):12-15
pages 12-15 views

Kontratseptsiya sredi zhitel'nits Moskvy, stradayushchikh ginekologicheskimi zabolevaniyami

Dikke G.

摘要

The article presents the results of the study involving 360 Moscow women aged 19-49 years, seeking medical care to obstetrician-gynecologist. Aim of this study was to investigate the frequency and structure of gynecological morbidity, the degree of realization of reproductive function, and methods for the regulation of fertility. According to the results of study, menstrual disorders (31 %), pelvic inflammatory disease (27 %), and hormone-dependent diseases (16 %) are predominant disorders in the structure of morbidity among Moscow women of childbearing age. Unmet demand for contraception is 37 %, while the maximum - 63 % - is in the older age group of 40-49 years. Modern contraceptive methods are used mainly by middle-aged women (combined oral contraceptives - 28 %, intrauterine device - 14 %). The most popular method of birth control for all age groups is a condom (average 68 %). Among women with gynecological diseases, increase of adherence to contraception can be achieved by high-quality consulting taking into account the existing disease, the needs and expectations of the patient and using innovative drugs with prolonged action.
Pharmateca. 2014;(12):16-21
pages 16-21 views

Otvechaya potrebnostyam podrostkov. V trende - prolongirovannaya kontratseptsiya, v fokuse - kachestvo konsul'tirovaniya

Bebneva T., Dikke G.

摘要

This review summarizes modern contraceptive strategy for adolsent girls, based on wider application of methods of prolonged reversible contraception. The safety of intrauterine contraceptive devices in this age group and the need for protection from sexually transmitted infections are discussed.
Pharmateca. 2014;(12):22-27
pages 22-27 views

Prolongirovannaya kontratseptsiya medroksiprogesteronom u zhenshchin raznykh sotsial'nykh grupp: komplaentnost' i pobochnye reaktsii

Belokrinitskaya T., Anokhova L., Frolova N., Anokhov S., Zhalsapova B.

摘要

The article presents the results of a prospective cohort study involving 85 healthy women of different social groups aged 18-36 years; the study was aimed to the comparative evaluation of adherence to the prolonged contraception with medroxyprogesterone and frequency of side effects. Side effects associated with prolonged contraception with medroxyprogesterone occurred 1.8 times less, and adherence to treatment was up to 36 higher in women of low-income social group than among women of middle-income social class, that perhaps influenced by the lifestyle and standard of living, nutrition and physical activity of women.
Pharmateca. 2014;(12):28-33
pages 28-33 views

Neispol'zovannyy rezerv v zashchite reproduktivnogo zdorov'ya, ili Plan «B»

Erofeeva L.

摘要

Emergency contraception is the easy, safe, most inexpensive, high effective, without contraindications, not requiring expensive examination, and hence most accessible method of contraception. This is still unused reserve for the reduction of unwanted pregnancies and abortions in Russia. The method is included in the list of essential drugs of the World Health Organization; therefore, this is an occasion for generalization of its use in centralized procurement of reproductive health programs in the Russian regions, as well as at the federal level.
Pharmateca. 2014;(12):34-39
pages 34-39 views

Predmenstrual'nyy sindrom: osobennosti diagnostiki i lecheniya

Unanyan A., Arakelov S., Polonskaya L., Guriev T., Morozova V.

摘要

The article discusses the modern concept of the complex pathogenesis of premenstrual syndrome (PMS) and approaches to its treatment. The diversity of clinical manifestations of PMS that causes a variety of therapeutic agents used is emphasized. Numerous studies suggests the great importance of magnesium deficiency as a factor of the development of PMS. This indicates the necessity of magnesium preparations (in particular, magnesium orotate) for all types of treatment of PMS.
Pharmateca. 2014;(12):40-45
pages 40-45 views

Novye metody terapii v lechenii kastratsionnorezistentnogo raka predstatel'noy zhelezy

Sokov D.

摘要

The problems of treatment of aggressive castration-refractory prostate cancer (CRPC), in which therapy docetaxel is traditionally used, are considered. The review presents the clinical results of use of several new drugs that increase survival in patients with CRPC. These include semisynthetic taxane cabazitaxel, peroral androgen receptor antagonist enzalutamide, and steroid CYP17 inhibitor abiraterone.
Pharmateca. 2014;(12):46-50
pages 46-50 views

Prakticheskie voprosy primeneniya gormonal'noy kontratseptsii zhenshchinami s kardial'nymi riskami i serdechnososudistymi zabolevaniyami

Podzolkova N., Podzolkov V., Pisarev M.

摘要

Article provides an overview of recent data on the effect of combined oral contraceptives on the key risk factors for cardiovascular disease (dyslipidemia, hypertension, smoking, obesity, diabetes, blood clotting). The recommendations for the use of hormonal contraception in patients with increased risk of cardiovascular events and cardiovascular disease based on WHO and the European professional societies documents are presented.
Pharmateca. 2014;(12):51-60
pages 51-60 views

Gipogonadizm u muzhchin

Manusharova R., Cherkezova E.

摘要

The article presents the results of treatment, as well as diagnosis and differential diagnosis of male hypogonadism. The analysis of current approaches to the treatment of hypogonadism was performed. It is shown that the main goal of treatment of the disease is hormone replacement therapy with testosterone. Growth hormone preparation or domestic drug somatotropin are used in case of low body height, if the growth zones are open. The use of drugs stimulating growth leads to an increase of body height by 10 to 12 cm. Defects of descent of testis should be corrected at an early age.
Pharmateca. 2014;(12):61-69
pages 61-69 views

Tselesoobraznost' i effektivnost' obuchayushchikh programm dlya patsientok, stradayushchikh predmenstrual'nym sindromom (rezul'taty prospektivnogo kogortnogo issledovaniya)

Ledina A., Prilepskaya V., Akimkin V.

摘要

A prospective cohort study(method of research - questionnaires) was performed. The study was aimed to the assessment of practicability and effectiveness of educational programs, including education for healthy lifestyle among female students suffering from premenstrual syndrome (PMS). According to the survey of 201 female students from the Kursk city, PMS was diagnosed in 112 (55.7 %) girls. They were divided into 2 groups. For Group I of students, training seminar on a specially designed program was held, and recommendations on diet, physical exercises, etc. were given. Adherence to the recommendations led to reduction of the PMS severity in 60.4 % of the respondents. For Group II of students, training seminar was held after repeated questionnaires. The study showed the practicability of the introduction and spread of educational programs and seminars for female students suffering from PMS.
Pharmateca. 2014;(12):70-72
pages 70-72 views

Patogeneticheskiy podkhod k primeneniyu al'fa-lipoevoy kisloty v lechenii erektil'noy disfunktsii u patsientov s sakharnym diabetom

Gusakova D., Efremov E.

摘要

The study was aimed to the assessment of the effectiveness of the alpha-lipoic acid at a dose of 600 mg per day in patients with diabetes mellitus (DM) type 2, erectile dysfunction (ED), disorders of libido, and other clinically significant symptoms of androgen deficiency. The study included 86 men with erectile dysfunction. The patient’s mean age was 51 year. Study group comprised 52 patients, control group included 34 patients. Evaluation of the effectiveness of the treatment was performed 12 weeks after administration of the drug. For the evaluation of the effectiveness of the therapy, validated questionnaires were used: the International Index of Erectile Function 5 (IIEF-5), and the Aging Male Simptoms (AMS) by Heinemann. The results of the study allow to recommend the alpha-lipoic acid as a pathogenic agent for the treatment of erectile dysfunction in patients with diabetes mellitus.
Pharmateca. 2014;(12):73-78
pages 73-78 views

Primenenie preparata roksitromitsin (Esparoksi) v lechenii negonokokkovogo uretrita u muzhchin

Pronkin E.

摘要

The use of standardized treatment regimens and drugs led to increasing resistance to known antibiotics. Leading European and American societies changed the conceptual approach to the treatment with antibacterial drugs that led to revision of established views on seemingly known and understandable problems. The article considers the potentials for the use of drug roxithromycin in the treatment of nongonococcal urethritis in men. Foreign and domestic clinical studies have confirmed the efficacy and safety of roxithromycin (Esparoxy).
Pharmateca. 2014;(12):79-82
pages 79-82 views

Respiratornye virusnye infektsii u beremennykh: analiz rezul'tatov laboratornogo monitoringa dlya vybora etiotropnoy terapii

Sharashkina N., Runikhina N., Burmenskaya O., Nepsha O., Donnikov A., Bystritskiy A., Trofimov D.

摘要

The article discusses current approaches to the diagnosis and treatment of acute respiratory viral infections and flu in pregnant women. Etiopathogenesis and clinical manifestation of these diseases are described; potentials for the use of real-time polymerase chain reaction (PCR) in the diagnosis of acute respiratory viral infections, as well as practical guidelines for the management of pregnancy and labour in women with acute respiratory viral infections and flu are discussed. In most cases, PCR has allowed to assign the most effective antiviral therapy in the first 24-48 hours after the onset of the disease.
Pharmateca. 2014;(12):83-87
pages 83-87 views
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