PATHOPHYSIOLOGICAL APPROACH AS A BASIS FOR THE SELECTION OF STRATEGY FOR THE SUCCESS TREATMENT OF TYPE 2 DIABETES MELLITUS


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Abstract

The paradigm of pathophysiological approach to the treatment of type 2 diabetes mellitus should consist in correcting the multiple disorders that underlie the progression of the disease, and different classes of drugs should be considered as complementary variants in the early combination therapy, but not as an additional reserve at the stage of inevitable therapeutic failure. Furthermore, the choice of therapy regimens must be carried out taking into account their effect on the function of pancreatic β-cells.

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About the authors

A. S Ametov

FSBEIFPE «Russian Medical Academy of Continuous Postgraduate Education» of RMH

Email: ametov.alexander@gmail.com
MD, Prof., Head of the Department of Endocrinology and Diabetology Moscow

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