EFFICIENCY OF COMBINED TREATMENT OF INFERTILITY ASSOCIATED WITH ENDOMETRIOSIS


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详细

A prospective, randomized trial to evaluate the effectiveness of combined treatment of endometriosis-associated infertility with the use of gonadotropin releasing hormone agonist (GRHA), gestagen (dienogest), and combined oral contraceptives in 100 patients was performed. It is shown that combined treatment of infertility in patients with endometriosis with the use of surgical method (coagulation and excision of foci of endometriosis) followed by the administration of GRHA or dienogest is effective for a third part of patients and does not differ depending on the variant of drug therapy. However, patients who received GRHA were 2 times more likely to have a nondeveloping pregnancy. The efficacy of both approaches to the treatment of endometriosis was high in both groups, but the frequency and severity of side effects were more significant in patients receiving GRHA.

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作者简介

N. Artymuk

Kemerovo State Medical University

Email: artymuk@gmail.com
MD, Prof., Head of the Department of Obstetrics and Gynecology № 2, Chief Freelance Specialist of the Russian Ministry of Health in Obstetrics and Gynecology in the Siberian Federal District, President of the Kemerovo Regional Public Organization «Association of Obstetricians and Gynecologists» Kemerovo

L. Danilova

Kemerovo Regional Clinical Perinatal Center n.a. Prof. L.A. Reshetova

Kemerovo

V. Chervov

Kemerovo State Medical University

Kemerovo

S. Rybnikov

Kemerovo Regional Clinical Perinatal Center n.a. Prof. L.A. Reshetova

Kemerovo

O. Tachkova

Kemerovo State Medical University

Kemerovo

参考

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