RESULTS OF THE EVALUATION OF HORMONAL AND METABOLIC PARAMETERS IN WOMEN WITH HYPOTHYROIDISM DEPENDING ON COMPENSATION OF DISEASE


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详细

Purpose: to evaluate hormonal and metabolic parameters and their relationship in women with hypothyroidism depending on the compensation of the disease. Methods. In order to support research objectives, 93 female patients with primary overt hypothyroidism and 20 controls were examined. The diagnosis of the disease was established on the basis of the clinical laboratory assessment. Results. Against the background of increased insulin resistance and compensatory hyperinsulinemia, atherogenic dysli-pidemia was detected in female patients with hypothyroidism. It was revealed that dysfunction of adipose tissue plays a certain role in the development of lipid metabolism disorders in hypothyroidism, and compensation of the disease does not lead to its normalization. The minimum concentration of vitamin 25-OH-D3 was found in women with decompensation of hypothyroidism.

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作者简介

A. Verbovoy

Samara State Medical University of RMH

Email: verbovoyy@rambler.ru
Department of Endocrinology Samara

I. Kapralova

Togliatti City Polyclinic № 4

Samara region, Togliatti

L. Sharonova

Samara State Medical University of RMH

Department of Endocrinology Samara

N. Verbovaya

Samara State Medical University of RMH

Department of Endocrinology Samara

I. Madyanov

Institute of Postgraduate Medical Training of the Ministry of Health of Chuvashia

Department of Therapy and Family Medicine Cheboksary

R. Galkin

Samara State Medical University of RMH

Department of Surgical Diseases № 1 Samara

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