RESULTS OF THE EVALUATION OF HORMONAL AND METABOLIC PARAMETERS IN WOMEN WITH HYPOTHYROIDISM DEPENDING ON COMPENSATION OF DISEASE
- Authors: Verbovoy A.F1, Kapralova I.Y.2, Sharonova L.A1, Verbovaya N.I1, Madyanov I.V3, Galkin R.A1
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Affiliations:
- Samara State Medical University of RMH
- Togliatti City Polyclinic № 4
- Institute of Postgraduate Medical Training of the Ministry of Health of Chuvashia
- Issue: No 4 (2018)
- Pages: 40-45
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/295235
- ID: 295235
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Abstract
Purpose: to evaluate hormonal and metabolic parameters and their relationship in women with hypothyroidism depending on the compensation of the disease. Methods. In order to support research objectives, 93 female patients with primary overt hypothyroidism and 20 controls were examined. The diagnosis of the disease was established on the basis of the clinical laboratory assessment. Results. Against the background of increased insulin resistance and compensatory hyperinsulinemia, atherogenic dysli-pidemia was detected in female patients with hypothyroidism. It was revealed that dysfunction of adipose tissue plays a certain role in the development of lipid metabolism disorders in hypothyroidism, and compensation of the disease does not lead to its normalization. The minimum concentration of vitamin 25-OH-D3 was found in women with decompensation of hypothyroidism.
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About the authors
A. F Verbovoy
Samara State Medical University of RMH
Email: verbovoyy@rambler.ru
Department of Endocrinology Samara
I. Yu Kapralova
Togliatti City Polyclinic № 4Samara region, Togliatti
L. A Sharonova
Samara State Medical University of RMHDepartment of Endocrinology Samara
N. I Verbovaya
Samara State Medical University of RMHDepartment of Endocrinology Samara
I. V Madyanov
Institute of Postgraduate Medical Training of the Ministry of Health of ChuvashiaDepartment of Therapy and Family Medicine Cheboksary
R. A Galkin
Samara State Medical University of RMHDepartment of Surgical Diseases № 1 Samara
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