The role of erythropoietin preparations in the treatment of anemia in oncologic patients


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Anemia is one of the most common conditions in oncologic patients. Most often, it is observed in patients with lung cancer, breast cancer, and oncogynecological patients. The clinical significance of anemia is associated with a negative impact on the quality of life, a decrease in exercise tolerance, the development of weakness and worsening treatment results. An effective and safe method for the correction of anemia is the use of erythropoietin preparations, which avoids frequent transfusions of red blood cells and reduces the risk of posttransfusion complications. Also, these drugs have neuroprotective, cardioprotective effects and increase the antioxidant activity of cells. This article analyzes foreign and domestic studies on the efficacy and safety of the use of erythropoietin preparations, indications and contraindications for their use, as well as criteria for correcting dosage regimens and drug withdrawal.

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作者简介

M. Abramov

N.N. Blokhin Scientific Research Center of Oncology

Email: mikhailabramov@newmail.ru
PhD 23, Kashirskoye Highway, Moscow 115478, Russian Federation

Y. Chikhareva

N.N. Blokhin Scientific Research Center of Oncology

Moscow, Russia

M. Manukyan

N.N. Blokhin Scientific Research Center of Oncology

Moscow, Russia

E. Prokofiev

N.N. Blokhin Scientific Research Center of Oncology

Moscow, Russia

G. Vyshinskaya

N.N. Blokhin Scientific Research Center of Oncology

Moscow, Russia

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