Metabolic comorbidity of endometritis after caesarean section

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Background. The present study is aimed at evaluation of the occurrence of postpartum (postoperative) infection by analyzing the information content of its predictors in patients with a somatic burden for the subsequent development of recommendations for treatment and prevention.

Objective. Assessment of the prevalence and structure of metabolic and endocrine diseases in puerperas with endometritis after caesarean section to determine their prognostic value as an independent predictor of the development of postoperative infectious and inflammatory complications.

Methods. A retrospective study of case histories and data from primary medical documentation of 406 puerperas with endometritis after caesarean section was carried out.

Results. The prevalence of pregravid obesity in puerperas with endometritis was 21.4% (every fifth patient with a BMI ≥30.00 kg/m2). Approximately with the same frequency (20.4%), various disorders of carbohydrate metabolism were diagnosed, gestational diabetes mellitus prevailed in their structure (78.3%). Obesity complicated the course of pregnancy 1.7 times more often in puerperas with endometritis compared with puerperas with an uncomplicated postoperative course (21.4 vs. 12.4%; χ2=8.36; P=0.004), and carbohydrate metabolism disorders – by 2.2 times (20.4 vs. 9.1%; χ2=14.391; P<0.001).

Conclusion. Concomitant metabolic diseases are significant predictors of the development of postoperative infectious and inflammatory complications in obstetrics.

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作者简介

Nikolay Korobkov

North-Western State Medical University n.a. I.I. Mechnikov; Sestroretskaya Multidisciplinary Clinic

编辑信件的主要联系方式.
Email: nikolai_korobkov@mail.ru
ORCID iD: 0000-0001-7279-2535
SPIN 代码: 4191-3581

Cand. Sci. (Med.), Associate Professor at the Department of Obstetrics and Gynecology n.a. S.N. Davydov, North-Western State Medical University n.a. I.I. Mechnikov, St. Petersburg, Russia

俄罗斯联邦, St. Petersburg; St. Petersburg

N. Bakulina

North-Western State Medical University n.a. I.I. Mechnikov

Email: nikolai_korobkov@mail.ru
ORCID iD: 0000-0003-4075-4096
俄罗斯联邦, St. Petersburg

N. Borovik

Sestroretskaya Multidisciplinary Clinic

Email: nikolai_korobkov@mail.ru
ORCID iD: 0000-0003-0835-6741
俄罗斯联邦, St. Petersburg

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2. Fig. 1. Structure and frequency of involved body systems in puerperas with endometritis after CS (n=648)

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3. Fig. 2. Structure and frequency of pregravid obesity in the examined patients (%)

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4. Fig. 3. Structure and frequency of detected disorders of carbohydrate metabolism in the examined patients (%)

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