Infective endocarditis of the aortic valve in a recipient of an orthotopic heart transplant. A case report

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Background. Infective endocarditis (IE) is one of the most severe diseases, which is attributable to the features of its pathogenesis, in particular the addition of immune complex damage to tissues and organs, which produces a variety of extracardiac symptoms. In-hospital mortality with drug treatment reaches 80%, with surgical treatment – 30%, and in the absence of treatment, mortality is 100%. In modern conditions, diagnosis and treatment of IE is a pressing problem in cardiology and cardiac surgery for many reasons, including an increase in morbidity, mainly due to primary endocarditis.

Description of the clinical case. In the presented clinical case, IE developed in a 49-year-old recipient of an orthotopic heart transplant 34 weeks after the operation. The clinical characteristics of the disease, the dynamics of instrumental and laboratory data are presented.

Conclusion. The presented clinical observation demonstrates the need for alertness of physicians of many specialties regarding the possibility of developing IE in the transplanted heart. The outcomes of IE in recipients with orthotopic heart transplantation may be similar compared to the general population, but patient survival is lower.

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作者简介

N. Kuleshevskaya

Aleksandro-Mariinsky Regional Clinical Hospital

Email: fduecn-2010@mail.ru
ORCID iD: 0009-0007-7255-5290
俄罗斯联邦, Astrakhan

O. Tsverkunova

Aleksandro-Mariinsky Regional Clinical Hospital

Email: fduecn-2010@mail.ru
ORCID iD: 0000-0002-0964-7252
俄罗斯联邦, Astrakhan

A. Antonova

Astrakhan State Medical University

编辑信件的主要联系方式.
Email: fduecn-2010@mail.ru
ORCID iD: 0000-0003-2581-0408

Cand. Sci. (Med.), Associate Professor

俄罗斯联邦, Astrakhan

T. Uklistaya

Astrakhan State Medical University

Email: fduecn-2010@mail.ru
ORCID iD: 0009-0005-5477-1913
俄罗斯联邦, Astrakhan

S. Yusupova

Aleksandro-Mariinsky Regional Clinical Hospital

Email: fduecn-2010@mail.ru
ORCID iD: 0009-0003-9816-1426
俄罗斯联邦, Astrakhan

T. Serdyukova

Astrakhan State Medical University

Email: fduecn-2010@mail.ru
ORCID iD: 0000-0003-0842-0336
俄罗斯联邦, Astrakhan

N. Petrova

Astrakhan State Medical University

Email: fduecn-2010@mail.ru
ORCID iD: 0009-0007-2562-8936
俄罗斯联邦, Astrakhan

G. Yamanova

Volgograd State Medical University

Email: fduecn-2010@mail.ru
ORCID iD: 0000-0003-2362-8979
俄罗斯联邦, Volgograd

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1. JATS XML
2. Fig. EchoCG of patient M. from 11/27/2023

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