FROM HOPE STUDY TO HOPE-2 AND HOPE-TOO STUDIES: DOES EXISTING PREVENTION STRATEGIES ARE NEED RADICAL IMPROVEMENT?
- Authors: Moiseev SV1, Fomin VV1, Saginova EA1, Moiseev S1, Fomin V1, Saginova E1
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Affiliations:
- Issue: No 4 (2009)
- Pages: 71-75
- Section: Articles
- URL: https://journals.eco-vector.com/2075-3594/article/view/245871
- ID: 245871
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Abstract
The article discusses results of the HOPE-2 study, which have demonstrated ineffectiveness of folic acid, B6 and B12 vitamins in terms of reducing the risk of cardiovascular complications, and results of HOPE-TOO study, the results of which confirmed the need for the administration of ACE inhibitors, in particular, ramipril, in all patients with high risk of cardiovascular complications. Use of vitamin E in them, on the contrary, it is inappropriate and can be dangerous.
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