Evaluation of the effectiveness of screening for sarcopenia in hemodialysis patients


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Abstract

Objective. evaluation of the effectiveness of sarc-f sarcopenia screening method in hemodialysis patients. material and methods. 317 patients who received treatment with program bicarbonate hemodialysis for 8.2±5.i years were examined; there were 171 women and 146 men, the mean age was 57.1 + 11.3 years. assessment of the presence of sarcopenia was performed using the method recommended by ewgsop (European working group on sarcopenia in older people). the sarc-f method was used for sarcopenia screening. results. when diagnosing sarcopenia according to the ewgsop recommendations, the sarc-f method showed an accuracy index for the diagnosis of sarcopenia at the level of 53%, i.e. the probability of error was almost equal to the probability of setting the correct diagnosis. for the sarc-f screening method, the area under the roc curve (AUC) did not exceed o.57, which indicates the low predictive value of this method as a method for sarcopenia screening. if there is a risk of developing sarcopenia according to the sarc-f method, there is a significant decrease in the main laboratory parameters, anthropometric parameters, and body composition indicators compared with indicators of patients with a negative result of sarcopenia screening. Conclusion. The use of the sarc-f sarcopenia screening method in hemodialysis patients is inappropriate due to its low predictive value.

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About the authors

Yulia V. Lavrishcheva

S.M. Kirov Military Medical Academy

Email: lavrischeva@gmail.com
Nephrologist at the Almazov National Medical Research Center, Teaching Assistant at the Department of Nephrology and Efferent Therapy Saint-Petersburg, Russia

Aleksandr A. Yakovenko

Pavlov First St. Petersburg State Medical University

Email: leptin-rulit@mail.ru
PhD in Medical Sciences, Associate Professor at the Department of Nephrology and Dialysis Saint-Petersburg, Russia

Aleksandr Sh. Rumyantsev

St. Petersburg State University

Email: rash.56@mail.ru
Doctor of Medical Sciences, Professor at the Department of Faculty Therapy, Faculty of Medicine Saint-Petersburg, Russia

Andrey N. Belskikh

S.M. Kirov Military Medical Academy

Corresponding Member of RAS, Doctor of Medical Sciences, Professor at the Department of Nephrology and Efferent Therapy Saint-Petersburg, Russia

References

  1. Isoyama N., Qureshi A.R., Avesani C.M., et al. Comparative associations of muscle mass and muscle strength with mortality in dialysis patients. Clin. J. Am. Soc. Nephrol. 2014;9(10):1720-28. doi: 10.2215/CJN.10261013.
  2. Battaglia Y, Galeano D., Cojocaru E., et al. Muscle-wasting in end stage renal disease in dialysis treatment: a review. G. Ital. Nefrol 2016;33(2):gin/33.2.7.
  3. Messina C., Maffi G, Vitale J.A., et al. Diagnostic imaging of osteoporosis and sarcopenia: a narrative review. Quant Imaging Med. Surg. 2018;8(1):86-99. doi: 10.21037/qims.2018.01.01.
  4. Giglio J., Kamimura M.A., Lamarca F., et al. Association of Sarcopenia With Nutritional Parameters, Quality of Life, Hospitalization, and Mortality Rates of Elderly Patients on Hemodialysis. J. Ren Nutr. 2018;28(3):197-207. doi: 10.1053/j.jrn.2017.12.003.
  5. Kittiskulnam P., Chertow G.M., Carrero J.J., et al. Sarcopenia and its individual criteria are associated, in part, with mortality among patients on hemodialysis. Kidney Int. 2017;92(1):238-247. doi: 10.1016/j.kint.2017.01.024.
  6. Cruz-Jentoft A.J., Baeyens J.P., Bauer J.M., et al. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010;39(4):412-423. doi: 10.1093/ageing/afq034.
  7. Barbosa-Silva T.G., Menezes A.M., Bielemann R.M., et al. Enhancing SARC-F: Improving Sarcopenia Screening in the Clinical Practice. J. Am. Med. Dir. Assoc. 2016;17(12):1136-1141. doi: 10.1016/j.jamda.2016.08.004.
  8. Guerri S., Mercatelli D., Aparisi Gomez M.P., et al. Quantitative imaging techniques for the assessment of osteoporosis and sarcopenia. Quant Imaging Med. Surg. 2018;8(1):60-85. doi: 10.21037/qims.2018.01.05.
  9. Arias-Guillen M., Perez E., Herrera P., et al. Bioimpedance Spectroscopy as a Practical Tool for the Early Detection and Prevention of Protein-Energy Wasting in Hemodialysis Patients. J. Ren Nutr. 2018;28(5):324-332. doi: 10.1053/j.jrn.2018.02.004.
  10. Sergi G., Trevisan C., Veronese N., et al. Imaging of sarcopenia. Eur. J. Radiol. 2016;85(8):1519-1524. doi: 10.1016/j.ejrad.2016.04.009.
  11. Tosato M., Marzetti E., Cesari M., et al. Measurement of muscle mass in sarcopenia: from imaging to biochemical markers. Aging Clin. Exp. Res. 2017;29(1):19-27. doi: 10.1007/s40520-016-0717-0.

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