Glomerulonephritis in patients with previous coronavirus infection. Risks and consequences

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Glomerulonephritis (GN) is a group of autoimmune inflammatory diseases that occur in the glomeruli of the kidneys and lead to a decrease in nephron function. Currently, the exact cause of GN is unclear, but there are several different putative mechanisms, among which the leading role is given to infectious agents and environmental factors. It is known that group B β-hemolytic streptococcus, human immunodeficiency virus, hepatitis B virus and hepatitis C virus, as well as parvovirus, have a tendency to develop kidney diseases. One of the potential agents may be the SARS-CoV-2 coronavirus, which has a fairly well-studied mechanism of binding to kidney structures and causing acute kidney injury, the central link in the pathogenesis of which is GN. In this article, the pathophysiological mechanisms of GN occurrence, possible ways of GN development associated with coronavirus infection are discussed, and possible medium- and long-term consequences for the corresponding patients are described. This article is written in the format of a literature review.

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作者简介

Ivan Polovikov

N.F.Sklifosovsky Institute of Clinical Medicine, Sechenov University

编辑信件的主要联系方式.
Email: polovikov_i_p@staff.sechenov.ru
ORCID iD: 0000-0002-3129-9397

Student

俄罗斯联邦, Moscow

Valeria Zakharova

Sechenov University

Email: zakharova_v_l@staff.sechenov.ru
ORCID iD: 0000-0001-5407-6906

Cand.Sci.(Med.), Associate Professor at the Department of Medical and Social Expertise, Emergency and Outpatient Therapy

俄罗斯联邦, Moscow

Zhanna Sizova

Sechenov University

Email: sizova_zh_m@staff.sechenov.ru
ORCID iD: 0000-0002-1242-7074

Dr.Sci.(Med.), Professor, Head of the Department of Medical and Social Expertise, Emergency and Outpatient Therapy, Institute of Postgraduate Education

俄罗斯联邦, Moscow

Natalia Lapidus

Sechenov University

Email: lapidus_n_i@staff.sechenov.ru
ORCID iD: 0000-0002-2222-836X

Cand.Sci.(Med.), Associate Professor at the Department of Medical and Social Expertise, Emergency and Outpatient Therapy

俄罗斯联邦, Moscow

Denis Shoikhet

Sechenov University

Email: shoykhet_d_a@staff.sechenov.ru
ORCID iD: 0009-0005-0420-446X

Teaching Assistant, Department of Microbiology, Virology and Immunology, Medical and Social Expertise

俄罗斯联邦, Moscow

Nadezhda Lenkova

Sechenov University

Email: lenkova_n_i@staff.sechenov.ru

Associate Professor at the Department of Clinical Pharmacology and Propaedeutics of Internal Diseases

俄罗斯联邦, Moscow

参考

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