FEATURES OF THE COLONIC MICROBIAL ENVIRONMENT IN INFANTS UNDER 2 YEARS OF AGE


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Abstract

Objective. To study the colonic microflora in infants under 2 years of age and a relationship between the hemolytic activity of Escherichia coli isolates and the genetic risk factors for diarrhea in them. Subjects and methods. The fecal microflora was examined in 219 infants aged less than 2 years with mild intestinal dysfunctions. Conventional procedures, diagnostic systems, and anaerobic techniques were applied. Results and conclusion. In the infants aged less than 2 years with moderate intestinal dysfunctions, the colonic microflora displayed a wide range of different microorganisms with anaerobic and facultative metabolism. Most children were found to have various impairments in the symbiotic microflora. There were atypical correlations between colonic obligate and transient symbionts. There was no association between the capacity of Escherichia coli to hemolyze sheep red blood cells and to decompose lactose and the class of the genetic risk factors for diarrhea.

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About the authors

I. A BOCHKOV

Central Research Institute of Epidemiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

Email: bochkovia@mail.ru
Moscow

L. P YURKO

Central Research Institute of Epidemiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

Moscow

S. A SHURALEVA

Central Research Institute of Epidemiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

Moscow

N. M YUDITSKAYA

Central Research Institute of Epidemiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

Moscow

E. S LAVRENOVA

Central Research Institute of Epidemiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

Moscow

I. V PLAKHTIY

Central Research Institute of Epidemiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

Moscow

N. N SLAVNOV

Central Research Institute of Epidemiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

Moscow

T. A KONOVALOVA

Central Research Institute of Epidemiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare

Moscow

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