CLINICAL AND LABORATORY FEATURES OF ABNORMALITIES IN THE CERVIX UTERI, EXTERNAL GENITALS, AND VAGINA IN HIV-INFECTED PATIENTS

Objective. To reveal the clinical and laboratory features of abnormalities in the cervix uteri, external genitals, and vagina in HIV- infected patients. Subjects and methods. The study enrolled 411 HIV- infected patients who had sought gynecologic care at Infectious Diseases Clinical Hospital Two, Moscow Healthcare Department, in 2006 to 2011. Groups 1 and 2 included 259 and 152 patients who had sought gynecologic care for abnormalities in external genitals and vagina, respectively. Results. In Group 1, the HIV-infected patients were more frequently found to have cervical dysplasia and cancer. In Group 2, the reason for seeking the care was external genital and vaginal warts in 49.3% of the patients. Antiretroviral therapy (ARVT) along with surgical removal of warts could achieve a two-year relapse-freeperiod in 94.7% ofthepatients. Conclusion. Cervical dysplasia and cancer are more frequently registered in the HIV-infected patients than in the general population. The detection rate of external genital and vaginal warts depends on the stage of HIV infection. ARVT and surgical removal of warts contributes to the increased duration of a relapse-free period.

HIV infection, gynecology, antiretroviral therapy