Herpesviridae and long-term subfebrility


Citar

Texto integral

Acesso aberto Acesso aberto
Acesso é fechado Acesso está concedido
Acesso é fechado Acesso é pago ou somente para assinantes

Resumo

Objective. To assess the clinical value and pathogenetic significance of herpesviruses in the development of longterm subfebrility in children. Subjects and methods. One hundred and twenty-seven children aged 6 months to 15years with long-term (3-week to 48-month) subfebrility were followed up. The children were admitted to the infection wards of the Central Clinical Hospital, the Morozov Children's Clinical Hospital, and the Russian Children's Clinical Hospital (Moscow). Results. Herpesvirus infection (HVI) markers were revealed in 112 (88.2%) children. Ofthem, 7(6.3%), 34 (30.4%), and 71 (63.3%) children were diagnosed as having acute, reactivated, and latent HVI, respectively. Conclusion. The clinical syndrome of long-term subfebrility should be considered to be one of the symptoms of an infectious disease running as a latent persistent process, less frequently as an active one.

Texto integral

Acesso é fechado

Sobre autores

T. Lebedeva

N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia

Email: Lebedevazx@mail.ru

N. Egorova

N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia

Email: uchaikin@list.ru

I. Koltunov

Morozov Children's Clinical Hospital

Email: info@mdgkb.mosgorzdrav.ru

N. Karazhas

N.F. Gamaleya Institute of Epidemiology and Microbiology, Ministry of Health of Russia

Email: karazas@rambler.ru

T. Rybalkina

N.F. Gamaleya Institute of Epidemiology and Microbiology, Ministry of Health of Russia

Email: rybalkinatn@mail.ru

M. Kalugina

N.F. Gamaleya Institute of Epidemiology and Microbiology, Ministry of Health of Russia

Email: happydoctor-mk@mail.ru

V. Uchaykin

N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia

Email: uchaikin@list.ru

Bibliografia

  1. Брязгунов И.П. Длительный субфебрилитет у детей: клиника, этиология, патогенез и лечение. М.: МИА, 2002. 240 с.
  2. Юлиш Е.И., Чернышева О.Е., Сорока Ю.А. Длительный субфебрилитет у детей. Возможные причины и подходы к терапии. Актуальные вопросы педиатрии 2011; 1(35): 67-72.
  3. Affronti M., Mansueto P., Soresi M. Low-grade fever: how to distinguish organic from non-organic forms. J. Clin. Pract. 2010; 3: 316-321.
  4. Гранитов В.М. Герпесвирусная инфекция. М: Медицинская книга, 2001. 82 с.
  5. Balachandran N., Amelse R.E. Identification of protein specific for human herpesvirus 6 infected human T cell. J. Virol. 1989; 63: 2835-2840.
  6. Yasukava M., Yakushijin Y. Specifity analysis of human CD4+ T-cell clones direct against human herpesvirus 6 (HHV-6), HHV-7, and human cytomegalovirus. J.Virol. 1993; 67: 6259-6264.
  7. Рыбалкина Т.Н., Каражас Н.В. Роль возбудителей оппортунистических инфекций в возникновении инфекционных осложнений у детей с иммунодефицитом и без выраженных нарушений иммунитета. Детские инфекции 2013; 12(3): 40-43.
  8. Санталова Г.В. Формирование соматической патологии у детей сперсистирующими инфекциями. Самара, 2005. 88 с.
  9. Семененя И.Н., Гурин В.Н. Теоретические и клинические аспекты проблемы субфебрилитета. Физиология человека 1995; 21(6): 127-136.

Arquivos suplementares

Arquivos suplementares
Ação
1. JATS XML
Baixar

Declaração de direitos autorais © Bionika Media, 2014