Epidemiological and economic efficiencies of immunization with the commercial influenza
- Authors: Saltykova T.S1, Romanenko V.V2, Minaeva O.V1
-
Affiliations:
- I. M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
- Ural State Medical University
- Issue: No 5 (2015)
- Pages: 65-71
- Section: Articles
- URL: https://journals.eco-vector.com/2226-6976/article/view/278335
- ID: 278335
Cite item
Open Access
Access granted
Abstract
Objective. To estimate the epidemiological and economic efficiencies of using the commercial vaccine Grippol® plus in the able-bodied adult population. Subjects and methods. The investigation was conducted at the Kamensk Uralsky metallurgical works, Sverdlovsk Region, during the 2010-2011 preseasonal and seasonal influenza incidence rises. It enrolled 2400 people who were divided into 2 groups: a study group (n = 1200) and a control one (n = 1200). Epidemiological, laboratory and statistical studies were used to analyze results. Results. In the study group, the incidence rate of influenza with regard to the serological verification of its diagnosis was significantly lower than that in the control group. The efficiency index for Grippol® plus vaccine was 2.15; its efficiency coefficient was 53.5%. Economic costs were 18563.74 and 14739.33 rubles per patient in the control and study groups, respectively. The economic efficiency of Grippol plus vaccine was 2129175.41 rubles or 5.8 rubles per invested ruble. Conclusion. The investigation showed the epidemiological and economic efficiencies of using the commercial vaccine Grippol® plus in the able-bodied adult population.
Full Text
About the authors
T. S Saltykova
I. M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
Email: saltykova.t.s.2012@gmail.com
V. V Romanenko
Ural State Medical University
Email: victor11@sky.ru
Yekaterinburg
O. V Minaeva
I. M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
Email: cherry1992@inbox.ru
References
- Ghendon Y. Influenza surveillance. Bull. WHO 1991; 69: 509-515.
- Glezen W.P. Serious morbidity and mortality associated with inflluenza epidemics. Epidemiol. Rev. 1982; 4: 25-42.
- Nichol K.L., Margolis K.L., Wuorenma J., von Sternberg T. The efficacy and cost effectiveness of vaccination against influenza among elderly persons living in the community. N. Engl. J. Med. 1994; 331: 778-784.
- Thompson W.W., Shay D.K., Weintraub E., Brammer L., Cox N., Anderson L.J., Fukuda K. Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA 2003; 289: 179-186.
- World Health Organization. Influenza Fact Sheet № 211. http ://www.who. int/mediacentre/factsheets/2003/fs211/en/ print.html.
- Ельшина Г.А., Тиньков А.Н., Борщук Е.Л., Яковенко С.В., Шарапов Д.Ф., Горбунов М.А., Лонская Н.И., Бектимиров Т.А. Оценка эпидемиологической и экономической эффективности вакцинопрофилактики гриппа среди работающих. Биопрепараты 2007; 12: 7-11.
- Nichol K.L. The efficacy, effectiveness and cost- effectiveness of inactivated influenza virus vaccine. Vaccine 2003; 21: 1769-1775.
- Шаханина И.Л., Радуто О.И., Осипова Л.А., Приказчикова Г.С. Экономическая эффективность вакцинопрофилактики: методика оценки. Эпидемиол. и инфекц. бол. 2004; 3: 12-16.
- Van Damme P., Beuteis P. Economic evaluation of vaccination. Pharmacoeconomics 1996; 9(Suppl. 3): 8-15.
- Nichol K.L., Lind A, Margolis K.L., Murdoch M., McFadden R., Hauge M., Magnan S., Drake M. The effectiveness of vaccination against influenza in healthy, working adults. N. Engl. J. Med. 1995; 333: 889-893.
- Doebbeling B.N., Edmond M.B., Davis C.S., Woodin J.R., Zeitler R.R. Influenza vaccination of health care workers: evaluation of factors that are important in acceptance. Prev. Med. 1997; 26: 68-77.
- Keech M., Scott A., Ryan P. The impact of influenza and influenza-like illness on productivity and healthcare resource utilization in a working population. Occup. Med. 1998; 48(2): 85-90.
- Бессмертный Б.С., Хейериц Л.Б. Оценка эффективности мероприятий по профилактике инфекционных болезней. М: Медицина, 1963. 207 с.
- Костинов М.П. Грипп: по пути безопасной вакцинации. Consilium medicum 2002; 5(7): 25-28.
Supplementary files
