Clinical characteristics of non-polio enterovirus infections in adult inpatients from the Krasnodar Territory
- Authors: Zhukova L.I.1,2, Shagina A.F.1,3, Rafeyenko G.K.1,4
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Affiliations:
- Kuban State Medical University, Ministry of Health of Russia
- Specialized Clinical Infectious Diseases Hospital, Ministry of Health of the Krasnodar Territory
- Clinical Center for AIDS Prevention and Control, Ministry of Health of the Krasnodar Territory
- Center for Hygiene and Epidemiology in the the Krasnodar Territory
- Issue: Vol 12, No 4 (2022)
- Pages: 34-39
- Section: Articles
- URL: https://journals.eco-vector.com/2226-6976/article/view/287978
- DOI: https://doi.org/10.18565/epidem.2022.12.4.34-9
- ID: 287978
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Abstract
Objective. To provide the clinical characteristics of non-polio enterovirus infections (NPEVIs) in adult inpatients from the Krasnodar Territory. Subjects and methods. The clinical symptoms of verified NPEVI were retrospectively analyzed in 111 adult patients admitted to the Specialized Clinical Infectious Diseases Hospital, Ministry of Health of the Krasnodar Territory, in 2016-2019. Results. Among the patients with NPEVI, young people with its moderate symptoms prevailed. More than half of the cases had this disease as exanthema of the mouth and extremities; the meningeal form occurred in a third of patients, NPEVI was the rarest form as an acute respiratory infection. The basic clinical signs of NPEVI in all its clinical forms were short-term febrile temperature, malaise, and weakness, upper respiratory tract symptoms, absolute monocytosis, and elevated C-reactive protein levels. In the meningeal form, the clinical and laboratory signs of serous meningitis were leading along with exanthema of the mouth and extremities - typical exanthema and enanthema. Conclusion. NPEVIs are difficult to diagnose in terms of sporadic morbidity, as confirmed by the frequency of initial misdiagnoses (99.1%). In addition to the mandatory verification of the diagnosis of NPEVI, additional laboratory tests are required to rule out clinically similar diseases.
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About the authors
Larisa I. Zhukova
Kuban State Medical University, Ministry of Health of Russia; Specialized Clinical Infectious Diseases Hospital, Ministry of Health of the Krasnodar Territory
Email: goukova@mail.ru
МD, Professor, Department of Infectious Diseases and Epidemiology
Anfisa F. Shagina
Kuban State Medical University, Ministry of Health of Russia; Clinical Center for AIDS Prevention and Control, Ministry of Health of the Krasnodar Territory
Email: anfisas@mail.ru
Graduate Student, Department of Infectious Diseases and Epidemiology
Galina K. Rafeyenko
Kuban State Medical University, Ministry of Health of Russia; Center for Hygiene and Epidemiology in the the Krasnodar Territory
Email: gorses@mail.kuban.ru
Graduate Student, Department of Infectious Diseases and Epidemiology
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