Epidemiological analysis of rabies outbreaks in the Trans-Baikal Region after transboundary drift of infection


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In 1980 to 2010, the Trans-Baikal region remained free of rabies. In 2011, the first cases of rabies in animals were recorded; outbreaks were later detected in several areas. Objective. To characterize the epidemiological features of rabies outbreaks recorded in Transbaikalia after a long period, during which no cases of th is disease were found. Material and methods. The authors conducted a descriptive epidemiological study of a series of outbreaks identified in the Republic of Buryatia and the Trans-Baikal Territory in 2011-2018. GIS technologies and phylogenetic analysis of virus isolates were used. Results. There were 262 cases of rabies in animals (35.5% of cases in wild animals, 7.2% in dogs and cats; 57.3% in agricultural animals). No human rabies cases were reported. Foxes (Vulpes vulpes) were the main natural reservoir of infection. Rabies virus isolates belonged to the steppe genetic lineage and differed from the viruses isolated in this region in the 1970s (Arctk-like lineage). Epidemiological and molecular genetic data are indicative of the transboundary introduction оf infection from Mongolia and China. Conclusion. The outbreaks of rabies in Trans-Baikal occurred due to the spreading of the steppe variant of the rabies virus in the eastern direction and its penetration into the peripheral areas of Mongol-type steppes. In 2011-2018 dogs and wolves were rarely involved in the circulation of the virus, unlike to the epizootics described in the 20th century, which is obviously associated with a change in the variant of the virus.

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作者简介

Aleksandr Botvinkin

Irkutsk State Medical University, Ministry of Health of Russia

Email: botvinkin_ismu@mail.ru

Ivan Zarva

Irkutsk State Medical University, Ministry of Health of Russia

Email: ivan_zarva@mail.ru

Nikolai Yakovchits

Irkutsk Anti-Plague Research Institute of Siberia and the Far East, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: nikolaybio@mail.ru

Renat Adelshin

Irkutsk Anti-Plague Research Institute of Siberia and the Far East, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; Irkutsk State University, Ministry of Science and Higher Education of the Russian Federation

Email: adelshin@gmail.com

Olga Melnikova

Irkutsk Anti-Plague Research Institute of Siberia and the Far East, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: melnikovaovit@gmail.com

Evgeni Andaev

Irkutsk Anti-Plague Research Institute of Siberia and the Far East, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: e.andaev@gmail.com

Mikhail Shulpin

Federal Centre for Animal Health

Email: shulpin@arriah.ru

Sergey Chupin

Federal Centre for Animal Health

Email: shulpin@arriah.ru

Rtem Metlin

Federal Centre for Animal Health

Email: artem.metlin@inbox.ru

Sergey Balakhonov

Irkutsk Anti-Plague Research Institute of Siberia and the Far East, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: balakhonov.irk@mail.ru

Sergey Khankhareev

Directorate for the Republic of Buryatia, Russian Federal Service for Supervision of Consumer Rights Protection and Human WellBeing

Email: sunoxr@03.rospotrebnadzor.ru

Svetlana Lapa

Directorate for the Trans-Baikal Territory, Russian Federal Service for Supervision of Consumer Rights Protection and Human WellBeing

Email: tur@75.rospotrebnadzor.ru

T. Istomina

Directorate for the Republic of Buryatia, Russian Federal Service for Supervision of Consumer Rights Protection and Human WellBeing

Email: sunoxr@03.rospotrebnadzor.ru

Inna Korotkova

Directorate for the Trans-Baikal Territory, Russian Federal Service for Supervision of Consumer Rights Protection and Human WellBeing

Email: osonnt@75.rospotrebnadzor.ru

Rimma Shoboeva

Directorate for the Republic of Buryatia, Russian Federal Service for Supervision of Consumer Rights Protection and Human WellBeing

Email: sunoxr@03.rospotrebnadzor.ru

Dmitry Kalugin

Veterinary Directorate for the Republic of Buryatia

Email: Kalugin.D@uvet.govrb.ru

Natalia Bakhlina

Veterinary Directorate for the Republic of Buryatia

Email: bakhlina.natasha@rambler.ru

Olga Zvereva

Buryat Republican Research and Production Veterinary Laboratory

Email: bvetlab@mail.ru

Vera Stepina

Trans-Baikal Territorial Veterinary Laboratory

Email: virusod@mail.ru

Aleksandr Ablov

Irkutsk Interregional Veterinary Laboratory

Email: imvl2004@mail.ru

Marina Koplik

Irkutsk Interregional Veterinary Laboratory

Email: imvl2004@mail.ru

Ekaterina Shkolnikova

Irkutsk Interregional Veterinary Laboratory

Email: imvl2004@mail.ru

Sergey Shchepin

Republican Service for Protection, Control, and Regulation of Use of Fauna Objects Referred to Objects of Hunting, Control, and Supervision in Environmental Management of the Republic of Buryatia

Email: info@rsbpn.govrb.ru

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