Causes of death in persons infected with the human immunodeficiency virus
- Authors: Kravchenko A.V.1, Ladnaia N.N.1, Pokrovsky V.V.1, Kozyrina N.V.1, Yurin O.G.1, Sokolova E.V.1, Chekryzhova D.G.1
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Affiliations:
- Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being
- Issue: Vol 13, No 3 (2023)
- Pages: 56-63
- Section: Original Investigations
- URL: https://journals.eco-vector.com/2226-6976/article/view/625316
- DOI: https://doi.org/10.18565/epidem.2023.13.3.56–63
- ID: 625316
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Abstract
Objective. Assessment of the causes of lethal outcomes associated with and not associated with HIV in patients with HIV infection in the Russian Federation for the period from 2008 to 2021.
Materials and methods. The results of a multi-year special study of the causes of deaths among those infected with HIV, conducted in 2007–2022, were summarized in all regions of the country.
Results. The most common etiological cause of death associated with HIV in 2019–2021, as in previous years, was mycobacterial infection. In 2018 and 2021, the number of patients who died from pneumocystis pneumonia, lymphoproliferative diseases and multiple infections increased. Cardiovascular and gastrointestinal diseases (primarily liver cirrhosis of viral etiology), as well as external causes and oncological diseases remain the main causes of deaths not associated with HIV infection. In 2021, 6.4% of people with HIV infection died from COVID-19 infection. Among the deceased, the proportion of patients receiving antiretroviral therapy was significantly less than in the population of patients with HIV infection who were under follow-up.
Conclusion. Reducing premature deaths from HIV infection and comorbidities can be achieved by increasing the coverage of people living with HIV with antiretroviral therapy and improving the diagnosis and treatment of comorbidities.
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About the authors
Alexey V. Kravchenko
Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being
Author for correspondence.
Email: alexey-kravtchenko@yandex.ru
ORCID iD: 0000-0001-7857-3763
Professor, МD, Leader Researcher
Russian Federation, MoscowNatalia N. Ladnaia
Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being
Email: n.ladnaya@hiv-russia.ru
ORCID iD: 0000-0003-2994-151X
Cand. Biol. Sci., Senior Researcher
Russian Federation, MoscowVadim V. Pokrovsky
Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being
Email: pokrovsky.vad@yandex.ru
ORCID iD: 0000-0002-9514-7288
Professor, Academician of the Russian Academy of Sciences, MD, Head, Specialized Research Department of Epidemiology and Prevention of AIDS
Russian Federation, MoscowNadezhda V. Kozyrina
Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being
Email: nad-kozyrina@yandex.ru
ORCID iD: 0000-0001-5134-0054
Cand. Med. Sci., Senior Researcher
Russian Federation, MoscowOleg G. Yurin
Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being
Email: oleg_gerald@mail.ru
ORCID iD: 0000-0003-1930-7486
МD, Leading Researcher
Russian Federation, MoscowEkaterina V. Sokolova
Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being
Email: ekaterinasokolova007@rambler.ru
ORCID iD: 0000-0002-2001-8772
Cand. Med. Sci, Researcher
Russian Federation, MoscowDaria G. Chekryzhova
Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being
Email: epid@hiv-russia.ru
ORCID iD: 0000-0003-0760-8257
Epidemiologist
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