Serological monitoring of collective immunity to hemorrhagic fever with renal syndrome in the Republic of Tatarstan and a number of subjects of the Russian Federation

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Abstract

Objective. Assessment of the collective immunity of the population to pathogens of hemorrhagic fever with renal syndrome (HFRS) in the territory of the Republic of Tatarstan and a number of constituent entities of the Russian Federation.

Materials and methods. An analysis of the HFRS epidemic situation was carried out based on operational monitoring data of the Reference Center for HFRS Monitoring of the Kazan Research Institute of Epidemiology and Microbiology of Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, an using the information provided by Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being institutions in the constituent entities of the Russian Federation. Blood sera for the presence of specific IgG antibodies to HFRS pathogens were examined using the VectoHanta-IgG enzyme-linked immunosorbent test system (Novosibirsk, Russia) during 2012–2021. The quantile ranking method was used.

Results. The regions of the Republic of Tatarstan were ranked according to the seropositive sera level from individuals who did not have HFRS in the period 2012–2021. Serological studies of the collective immunity of the population of the Republics of Bashkortostan (2019, 2020), Udmurtia (2019), Ulyanovsk region (2019), Republic of Mordovia (2021), Kostroma (2021) and Chelyabinsk regions (2020, 2021) to HFRS pathogens were carried out.

Conclusion. The serological studies carried out made it possible to assess the state of natural immunity of the population to hantaviruses, which provides an objective assessment of the risk of infection of the population in endemic areas.

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About the authors

Tatiana A. Savitskaya

Kazan Research Institute of Epidemiology and Microbiology of Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Author for correspondence.
Email: tatasav777@mail.ru
ORCID iD: 0000-0002-6229-0387

Cand. Biol. Sci., Head, Laboratory of Epidemiology and Natural Focal Infections

Russian Federation, Kazan

Vladimir A. Trifonov

Kazan Research Institute of Epidemiology and Microbiology of Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: vatrifonov@mail.ru
ORCID iD: 0000-0002-1810-1825

Cand. Med. Sci., Leading Researcher

Russian Federation, Kazan

Elena V. Agafonova

Kazan Research Institute of Epidemiology and Microbiology of Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; Kazan State Medical University

Email: agafono@mail.ru
ORCID iD: 0000-0002-4411-8786

Cand. Med. Sci., Head, Clinical Diagnostic Laboratory, Kazan Research Institute of Epidemiology and Microbiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; Associate Professor, Kazan State Medical University, Ministry of Health of Russia

Russian Federation, Kazan; Kazan

Guzel S. Isaeva

Kazan Research Institute of Epidemiology and Microbiology of Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; Kazan State Medical University

Email: guisaeva@rambler.ru
ORCID iD: 0000-0002-1462-8734

MD, Рrofessor, Deputy Director, Kazan Research Institute of Epidemiology and Microbiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; Head, Department of Microbiology, Kazan State Medical University, Ministry of Health of Russia

Russian Federation, Kazan; Kazan

Irina D. Reshetnikova

Kazan Research Institute of Epidemiology and Microbiology of Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; Kazan (Volga Region) Federal University

Email: reshira@mail.ru
ORCID iD: 0000-0002-3584-6861

Cand. Med. Sci., Deputy Director, Kazan Research Institute of Epidemiology and Microbiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; Associate Professor Kazan (Volga Region) Federal University

Russian Federation, Kazan; Kazan

Dina N. Petrova

Kazan Research Institute of Epidemiology and Microbiology of Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: rcglps@yandex.ru
ORCID iD: 0000-0002-6682-0760

Junior Researcher

Russian Federation, Kazan

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