Clinical observations of the course of a new coronavirus infection in patients with chronic pulmonary tuberculosis and respiratory failure
- Authors: Dobin V.L.1, Nikolaev A.N.1, Martynov V.A.1
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Affiliations:
- Academician I.P. Pavlov Ryazan State Medical University
- Issue: Vol 13, No 4 (2023)
- Pages: 115-120
- Section: Exchange of Experience
- URL: https://journals.eco-vector.com/2226-6976/article/view/625541
- DOI: https://doi.org/10.18565/epidem.2023.13.4.115-20
- ID: 625541
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Abstract
Objective. Analysis of the clinical course of a new coronavirus infection in patients with chronic pulmonary tuberculosis (TB) and respiratory failure.
Materials and methods. We analyzed 6 case histories of patients with TB who fell ill with COVID-19 and were treated in a temporary infectious diseases department deployed at an anti-tuberculosis dispensary in 2021. The clinical course of a new coronavirus infection in 3 patients with chronic pulmonary T and respiratory failure in comparison with 3 patients without symptoms respiratory failure of was described in detail. In total, 21 confirmed cases of COVID-19 were identified in the Ryazan region among 217 TB patients registered at the TB dispensary, which amounted to 9.67%. All TB patients recovered from COVID-19. None of them received anti-cytokine therapy or required mechanical ventilation.
Results. In 4 out of 6 patients with co-infection, COVID-19 occurred with symptoms of moderate intoxication and viral colonization of the upper respiratory tract, without damage to the lung tissue, in 2 – with such damage (in one – CT-1, in the second – CT-2). Patients with background respiratory failure had a moderate course, and those without signs of respiratory failure had a mild course of COVID-19.
Conclusion. Despite the pronounced initial background and somatic burden, 3 patients with chronic pulmonary TB and respiratory failure had a moderate course of coronavirus infection.
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About the authors
Vitally L. Dobin
Academician I.P. Pavlov Ryazan State Medical University
Author for correspondence.
Email: viladob@gmail.com
SPIN-code: 7954-9457
MD, Professor, Department of Infectious Diseases and Phthisiology
Russian Federation, RyazanAlexey N. Nikolaev
Academician I.P. Pavlov Ryazan State Medical University
Email: nalex12@mail.ru
ORCID iD: 0000-0002-3625-602X
Cand. Med. Sci., Assistant, Department of Infectious Diseases and Phthisiology
Russian Federation, RyazanVladimir A. Martynov
Academician I.P. Pavlov Ryazan State Medical University
Email: dr.martinov@mail.ru
ORCID iD: 0000-0002-0117-0613
SPIN-code: 2378-4380
MD, Professor, Head, Department of Infectious Diseases and Phthisiology
Russian Federation, RyazanReferences
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