Current pathogens of surgical site infections

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Abstract

The article presents a review of domestic and foreign sources on the problem of surgical site infections over the past 5 years. The methodology included a systematic search using keywords, selection of peer-reviewed articles, analysis of data on etiology, level of resistance to antibacterial drugs and postoperative complications. The main causative agents of surgical site infections are microorganisms of the ESKAPE group, which have multiple drug resistance. These pathogens are able to adapt to hospital conditions due to mutations, biofilm formation and horizontal gene transfer. To solve this problem, it is necessary to revise measures aimed at preventing the development of the infectious process, conduct active monitoring, which consists of identifying and analyzing pathogenic microorganisms, control over the resistance of pathogens to antimicrobial drugs, strictly justified use of antibiotics in clinical practice and improve antimicrobial chemotherapy regimens.

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About the authors

Artyom M. Morozov

Tver State Medical University; City Clinical Hospital No. 7

Author for correspondence.
Email: ammorozovv@gmail.com
ORCID iD: 0000-0003-4213-5379

Cand. Med. Sci., Associate Professor at the Department of General Surgery; Surgeon

Russian Federation, Tver; Tver

Alexey N. Sergeev

Tver State Medical University; City Clinical Hospital No. 7

Email: dr.nikolaevich@mail.ru
ORCID iD: 0000-0002-9657-8063

MD, Associate Professor, Head of the Department of General Surgery; Surgeon

Russian Federation, Tver; Tver

Julia V. Chervinets

Tver State Medical University

Email: julia_chervinec@mail.ru
ORCID iD: 0000-0001-9209-7839

MD, Professor, Head of the Department of Microbiology and Virology with a Course in Immunology

Russian Federation, Tver

Ekaterina A. Fisyuk

Tver State Medical University

Email: feedrfnz@mail.ru
ORCID iD: 0009-0000-0582-7398

4th-Year Student

Russian Federation, Tver

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