CHANGES IN THE DEGREE OF HEPATIC FIBROSIS DUE TO THREE-YEAR ENTECAVIR THERAPY IN A PATIENT WITH CHRONIC HEPATITIS B WITH AN OUTCOME TO HEPATIC CIRRHOSIS
- Authors: ZNOIKO O.O1, DUDINA K.R1, SAFIULLINA N.K.1, KARANDASHOVA I.V2, CHULANOV V.P2
-
Affiliations:
- A.J. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health and Social Development of Russia
- Central Research Institute of Epidemiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare
- Issue: No 6 (2012)
- Pages: 65-67
- Section: Articles
- URL: https://journals.eco-vector.com/2226-6976/article/view/276330
- ID: 276330
Cite item
Open Access
Access granted
Abstract
The paper describes a clinical case demonstrating the reversal of hepatic fibrosis during three-year entecavir therapy in a patient with chronic hepatitis B with an outcome to hepatic cirrhosis.
Full Text
About the authors
O. O ZNOIKO
A.J. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health and Social Development of Russia
Email: olgaznoyko@yandex.ru
K. R DUDINA
A.J. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health and Social Development of Russia
N. KH SAFIULLINA
A.J. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health and Social Development of Russia
I. V KARANDASHOVA
Central Research Institute of Epidemiology, Russian Inspectorate for the Protection of Consumer Rights and Human WelfareMoscow
V. P CHULANOV
Central Research Institute of Epidemiology, Russian Inspectorate for the Protection of Consumer Rights and Human WelfareMoscow
References
- Coco B., Oliveri F., Maina A.M. et al. Transient elastography: a new surrogate marker of liver fibrosis influenced by major changes of transaminases. J. Viral. Hepat. 2007; 14(5): 360—369.
- Arena U., Vizzutti F., Corti G. et al. Acute viral hepatitis increases liver stiffness values measured by transient elastography. Hepatology 2008; 47(2): 380—384.
- Sagir A., Erhardt A., Schmitt M., Häussinger D. Transient elastography is unreliable for detection of cirrhosis in patients with acute liver damage. Hepatology 2008; 47(2): 592—595.
- EASL clinical practice guidelines: Management of chronic hepatitis B virus infection. J. Hepatol. 2012; 57(1): 167—185. Epub 2012 Mar 20.
- Enomoto M., Mori M., Ogawa T. et al. Usefulness of transient elastography for assessment of liver fibrosis in chronic hepatitis B: Regression of liver stiffness during entecavir therapy. Hepatol. Res. 2010; 40(9): 853—861.
- Chang T.T., Liaw Y.F., Wu S.S. et al. Long-term entecavir therapy results in the reversal of fibrosis/cirrhosis and continued histological improvement in patients with chronic hepatitis B. Hepatology 2010; 52(3): 886—893.
- Schiff E.R., Lee S.S, Chao Y.C. et al. Long-term treatment with entecavir induces reversal of advanced fibrosis or cirrhosis in patients with chronic hepatitis B. Clin. Gastroenterol. Hepatol. 2011; 9(3): 274—276.
Supplementary files
