Clinical and pathogenetic aspects of genital herpetic infection

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Abstract

An analysis of domestic and foreign literature on the prevalence, pathogenesis and features of the clinical course of genital herpes in the modern period is presented. The increasing etiological role of herpes simplex virus type 1 (HSV-1) in this disease has been shown. Data on the great importance of cellular immunity factors in the development of severe forms and relapses of genital herpes are presented. Modern recommendations for the treatment of genital herpes in different categories of patients are discussed.

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About the authors

Natalia Yu. Pshenichnaya

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; M.F. Vladimirsky Moscow Regional Research Clinical Institute

Author for correspondence.
Email: pshenichnaya@cmd.su
ORCID iD: 0000-0003-2570-711X

Professor, MD, Deputy Director for Clinical and Analytical Work, Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; Professor, Department of Infectious Diseases, M.F. Vladimirsky Moscow Regional Research Clinical Institute

Russian Federation, Moscow; Moscow

Elena B. Romanova

Rostov Research Institute of Microbiology and Parasitology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: eromanova1961@yandex.ru
ORCID iD: 0000-0002-6885-6126

MD, Associate Professor, Chief Researcher, Head, Laboratory of Sanitary and Parasitological Monitoring, Medical Parasitology and Immunology, Rostov Research Institute of Microbiology and Parasitology

Russian Federation, Rostov-on-Don

Tatiana I. Tverdokhlebova

Rostov Research Institute of Microbiology and Parasitology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; Rostov State Medical University, Ministry of Health of Russia

Email: rostovniimp@mail.ru
ORCID iD: 0000-0002-3912-0291

MD, Director, Rostov Scientific Research Institute of Microbiology and Parasitology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; Professor, Department of Epidemiology, Rostov State Medical University, Ministry of Health of Russia

Russian Federation, Rostov-on-Don; Rostov-on-Don

Galina V. Gopatsa

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: gopatsa@cmd.su
ORCID iD: 0000-0001-8703-7671

Cand. Med. Sci., Senior Researcher

Russian Federation, Moscow

Alexander G. Suladze

Rostov Research Institute of Microbiology and Parasitology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: hivrost@mail.ru
ORCID iD: 0000-0002-9051-1220

Cand. Med. Sci., Chief Physician

Russian Federation, Rostov-on-Don

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