Prediction of an outcome in Crimean hemorrhagic fever


Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

When medical care is rendered to seriously ill patients with Crimean hemorrhagic fever (CHF), there is an increased risk of healthcare-associated infection (HCAI) at first- and second-level hospitals. There is a need for the uniform assessment of disease severity, according to which the patient at high risk of death should be immediately transferred to a third-level hospital. Objective. To develop a procedure for assessing the risk of death in patients with CHF, by determining the clinical and laboratory values available at first-/second-level hospitals on the day of hospitalization. Materials and methods. By analyzing four procedures for evaluating the severity of the condition in patients with CHF, the investigators designed a mortality risk prediction scale based on 12 clinical and laboratory parameters and 2-4 gradations of each parameter, which was reflected in 32 criteria of the scale. The scale was tested based on the Epidemiologia i infekcionnye bolezni. aktual'nye voprosy retrospective analysis of case records of 52 patients with CHF who had been treated at the hospitals of the Turkestan Region, Republic of Kazakhstan, in 2000-2018. Results. The patients’ clinical and laboratory values were rated using the designed point scale for assessing the risk of death in patients with CHF. Each parameter was assigned a certain number of scores and then their total amount was determined. When the patient had a total score of > 11, he was predicted to be at high risk of an unfavorable outcome. When the total score was < 11, the risk for an adverse outcome was considered to be low in patients with CHF. The sensitivity of the proposed procedure was 100%; its specificity was 98%, and the predicted value was 90%. Conclusion. The proposed procedure with a high probability allows prediction of a poor outcome of CHF; it should be used at first- and second-level hospitals to optimize healthcare provision to patients with this disease and to prevent HCAI.

Толық мәтін

Рұқсат жабық

Авторлар туралы

Gulzhan Abuova

South Kazakhstan Medical Academy

Email: dr.abuova@gmail.com
Cand. Med. Sci., Head, Department of Infectious Diseases and Dermatovenerology, Prof. Shymkent, Republic of Kazakhstan

Nataliya Pshenichnaya

National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Ministry of Health of Russia; Rostov State Medical University, Ministry of Health of Russia

Email: natalia-pshenichnaya@yandex.ru
MD, Infectiologist, National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Ministry of Health of Russia; Leading Researcher, Rostov State Medical University, Ministry of Health of Russia, Rostov-on-Don, Prof. Moscow, Russia

Farida Berdalieva

South Kazakhstan Medical Academy

Email: fberdalieva@mail.ru
Cand. Med. Sci., Associate Professor, Department of Infectious Diseases and Dermatovenereology Shymkent, Republic of Kazakhstan

Bakytjan Khodzhabekov

South Kazakhstan Medical Academy

Email: 79281905477@yandex.ru
Cand. Med. Sci., Associate Professor, Department of Infectious Diseases and Dermatovenereology Shymkent, Republic of Kazakhstan

Larisa Ermakova

Rostov State Medical University, Ministry of Health of Russia; Rostov Research Institute of Microbiology and Parasitology, Russian Federal Service for Surveillance of Consumer Rights Protection and Human Well-Being

Cand. Med. Sci., Assistant, Department of Infectious Diseases, Ministry of Health of Russia; Head, Clinic ofInfectious and Parasitic Diseases, Rostov Research Institute of Microbiology and Parasitology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being Rostov-on-Don, Russia

Әдебиет тізімі

  1. Ergönül Ö. Crimean-Congo haemorrhagic fever. The Lancet Infectious Diserses 2006; 04): 203-14.
  2. Волынкина А.С., Пакскина Н.Д., Котенев Е.С., Малецкая О.В., Шапошникова Л.И.,Колосов А.В., Василенко Н.Ф., Манин Е.А., ПрислегинаД.А., Яцменко Е.В., Куличенко А.В. Анализ заболеваемости Крымской геморрагической лихорадкой в Российской Федерации в 2009-2018 гг. и прогноз на 2019 г. Проблемы особо опасных инфекций 2019; (1): 26-31 https://doi.org/10.21055/0370-1069-2019-1-26-31
  3. Nurmakhanov T., Sansyzbaev Y., Atshabar B. et al. Crimean-Congo haemorrhagic fever virus in Kazakhstan (1948-2013). Int. J. Infect. Dis. 2015; 38: 19-23. doi: 10.1016/j.ijid.2015.07.007 •
  4. IMAI district clinician manual: hospital care adolescents and adults: guidelines for the management of illnessess with limited-resources. World Health Organization, 2011. https://www.who.int/ influenza/patient_care/DCM_ Volume_1.pdf
  5. Al-Abri S.S., Al Abaidani I., Fazlalipour M., Mostafavi E., Leblebicioglu H., Pshenichnaya N., Nguyen T.M.N. Current status of Crimean-Congo haemorrhagic fever in the World Health Organization Eastern Mediterranean Region: issues, challenges, and future directions. Int. J. Infect. Dis. 2017; 58: 82-9.
  6. Pshenichnaya N.Y., Nenadskaya S.A. Probable Crimean-Congo hemorrhagic fever virus transmission occurred after aerosolgenerating medical procedures in Russia: nosocomial cluster. Int. J. Infect. Dis. 2015; 33: 120-2.
  7. Pshenichnaya N.Y., Leblebicioglu H., Bozkurt I. et al. Crimean-Congo hemorrhagic fever in pregnancy: A systematic review and case series from Russia, Kazakhstan and Turkey. Int. J. Infect. Dis. 2017; 58, 58-64.
  8. Naderi H.R., Sarvghad M.R., Bojdy A., Hadizadeh M.R., Sadeghi R., Sheybani F. Nosocomial outbreak of Crimean-Congo haemorrhagic fever. Epidemiology and Infection, 2011; 139(6): 862-6.
  9. Щелканов М.Ю, Колобухина Л.В., Москвина Т.М., Аушев И.Д., Картоев А.А., Келли Е.И., Меркулова Л.Н., Гренкова Е.П., Самохвалов Е.И., Петряев В.Г., Серобян А.Г., Климова Е.А., Галкина И.В., Малышев Н.А., Аристова В.А., Славскин A.А., Лукьянова Н.А., Дерябин П.Г., Громашевский B.Л., Ефременко В.И., Онищенко Г.Г., Львов Д.К. Выявление циркуляции вируса Крымской-Конго геморрагической лихорадки в предгорных степях Северного Кавказа. Вопр. вирусол. 2005; (5): 9-15
  10. Swanepoel R., Gill D. E., Shepherd A. J., Leman P. A., Mynhardt J. H., Harvey S. The clinical pathology of Crimean-Congo hemorrhagic fever. Rev. Infect. Dis. 1989; 11(Suppl. 4): 794-800.
  11. Dokuzoguz B., Celikbas A.K., Gök §.E., Baykam N., Eroglu M.N., Ergönül Ö. Severity scoring index for Crimean- Congo hemorrhagic fever and the impact f ribavirin and corticosteroids on fatality. Clin. Infect. Dis., 2013; 57(9): 1270 -4.
  12. Bakir M., Engin A., Gozel M.G., Elaldi N., Kilickap S., Cinar Z. A new perspective to determine the severity of cases with Crimean-Congo hemorrhagic fever. Journal of Vector Borne Diseases 2012; 49(2): 105-10.
  13. Bakir M., Gözel M.G., Köksal I., Asik Z., Günal Ö., Yilmaz H., Engin A. Validation of a severity grading score (SGS) system for predicting the course of disease and mortality in patients with Crimean-Congo hemorrhagic fever (CCHF). Eur. J. Clin. Microbiol. Infect. Dis. 2015; 34(2): 325-30.
  14. Клинический протокол диагностики и лечения «Конго-Крымская лихорадка». Рекомендован Экспертным советом РГП на ПХВ «Республиканский центр развития здравоохранения» МЗСР РК от 12 12 декабря 2014 года № 9. https://online. zakon.kz/Document/?doc_id= 39136838

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