Analysis of the results of monitoring the pathogens of acute respiratory viral infection, influenza, and COVID-19 in asymptomatic individuals

Мұқаба

Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

Objective. To monitor the circulation of pathogens of acute respiratory viral infections (ARVIs), influenza, and COVID-19 among people without symptoms of acute respiratory infections (ARIs) in different age groups and to identify the features of the epidemic process by monitoring their pathogens on a weekly basis.

Subjects and methods. The results of monitoring the pathogens of ARVIs, influenza, and COVID-19 were analyzed in individuals without symptoms of ARIS in January 2021 to August 2022. Smears from the naso- and oro-pharynx were tested by a PCR assay. The data were statistically processed using the MedCalc. program.

Results. A total of 273,846 people who had no symptoms of ARI were examined; 16,665 (6.09%) had positive results of them with a positive result (6.09%). In the structure of the detected viruses, Rhinovruses (46%) predominate; there were SARs-COV-2 (15%), human coronaviruses (229E, OC43, HKUI, and NL63) (12%); the proportion of the rest was 0.05 to 9%.

Conclusion. Differences were established in the prevalence of SARS-CoV-2 and rhinovirus in the age groups. The data were obtained, which indicated the presence of the asymptomatic transient carriage of ARVI pathogens during the increased morbidity period characteristic for rhinoviruses, SARS-CoV-2 and rhinovirus in age groups have been established. The data were obtained, which indicated the presence of asymptomatic transient carriage of ARVI pathogens during the increased morbidity period characteristic for orhinoviruses, SARS-CoV-2, and epidemic human coronaviruses. A direct average correlation was found between the infection of SARS-CoV-2 asymptomatic individuals and the incidence of COVID-19. Differences were established in the prevalence of SARS-CoV-2 and rhinovirus in age groups have been established. Data were obtained, which suggest that there is an asymptomatic transient carriage of ARVI pathogens during the increased morbidity period characteristic for rhinoviruses, SARS-CoV-2 and epidemic human coronaviruses. A direct average correlation was found between the infection of SARS-CoV-2 in asymptomatic individuals and the incidence of COVID-19.

Толық мәтін

Рұқсат жабық

Авторлар туралы

Marina Mamoshina

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection, and Human Well-Being

Хат алмасуға жауапты Автор.
Email: mamoshina@cmd.su
ORCID iD: 0000-0002-1419-7807

Junior Researcher, Laboratory for the Molecular Diagnosis and Epidemiology of Respiratory Tract Infections

Ресей, Moscow

Svetlana Yatsyshina

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection, and Human Well-Being

Email: svetlana.yatsyshina@pcr.ms
ORCID iD: 0000-0003-4737-941X

Cand. Biol. Sci.; Head, Laboratory for the Molecular Diagnosis and Epidemiology of Respiratory Tract Infections

Ресей, Moscow

Vasily Akimkin

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection, and Human Well-Being

Email: akimkin@pcr.ms
ORCID iD: 0000-0003-4228-9044

Academician of the Russian Academy of Sciences, MD, Professor, Director

Ресей, Moscow

Әдебиет тізімі

  1. Suzuki T., Aizawa K., Shibuya K., Yamanaka S., Anzai Y., Kurokawa K. et al. Prevalence of Asymptomatic SARS-CoV-2 Infection in Japan. JAMA Netw Open. 2022; 5(12): e2247704. doi: 10.1001/jamanetworkopen.2022.47704
  2. Ma Q., Liu J., Liu Q., Kang L., Liu R., Jing W. et al. Global Percentage of Asymptomatic SARS-CoV-2 Infections Among the Tested Population and Individuals With Confirmed COVID-19 Diagnosis: A Systematic Review and Meta-analysis. JAMA Netw Open. 2021; 4(12): e2137257. doi: 10.1001/jamanetworkopen.2021.37257.
  3. Пшеничная Н.Ю., Гопаца Г.В., Углева С.В. Сергевнин В.И., Кудрявцева Л.Г., Лазарьков П.В. Эпидемиологические аспекты респираторных инфекций верхних и нижних отделов дыхательных путей в период пандемии COVID- 19. Эпидемиол. инфекц. болезни. Актуал. вопр. 2022; 12 (4): 72–6. doi: 10.18565/epidem.2022.12.4.72-6. Pshenichnaya N.Yu., Gopatsa G.V., Ugleva S.V., Sergevnin V.I., Kudryavtseva L.G., Lazarkov P.V. [Epidemiological aspects of upper and lower respiratory tract infections during the COVID-19]. Epidemiоlоgy and infectious diseases. Сurrent items. 2022; 12(4): 72–6. (In Russ.). doi: 10.18565/epidem.2022.12.4.72-6
  4. Еженедельный национальный бюллетень по гриппу и ОРВИ за 36 неделю 2022 г. (05.09.22–11.09.22). М.: ФГБУ «НИИ гриппа им. А.А. Смородинцева» Минздрава России. https://www.influenza.spb.ru/system/epidemic_ situation/laboratory_diagnostics/?year=2022&week=36. [Weekly National bulletin on influenza and Acute Respiratory Viral Infections for the 36th week of 2022 (05.09.22–11.09.22)]. Moscow: A.A. Smorodintsev Influenza Research Institute of the Ministry of Health of the Russian Federation. https://www.influenza.spb.ru/system/epidemi_situation/ laboratory_diagnostics/?year=2022&week=36
  5. Geddes L. Puzzle over viral load. New Sci. 2020; 245(3276): 8. doi: 10.1016/S0262-4079(20)30658-8
  6. Joynt G.M., Wu W.K. Understanding COVID-19: what does viral RNA load really mean? Lancet Infect. Dis. 2020; 20: 635–6. doi: 10.1016/S1473-3099(20)30237-1
  7. Rao S.N., Manissero D., Steele V.R., Pareja J. A Systematic Review of the Clinical Utility of Cycle Threshold Values in the Context of COVID-19. Infect. Dis. Ther. 2020; 9(3): 573–86. doi: 10.1007/s40121-020-00324-3.
  8. Tom M., Mina M.J. To interpret the SARS-CoV-2 test, consider the cycle threshold value. Clin. Infect. Dis. 2020; 71(16): 2252-2254. doi: 10.1093/cid/ciaa619
  9. Rabaan A. A., Tirupathi R., Sule A. A., Aldali J., Mutair A. A., Alhumaid S. et al. Viral Dynamics and Real-Time RT-PCR Ct Values Correlation with Disease Severity in COVID-19. Diagnostics (Basel) 202115; 11(6): 1091. doi: 10.3390/diagnostics11061091.
  10. La Scola B., Le Bideau M., Andreani J., Hoang V. T., Grimaldier C., Colson P. et al. Viral RNA load as determined by cell culture as a management tool for discharge of SARS-CoV-2 patients from infectious disease wards. Eur. J. Clin. Microbiol. Infect. Dis. 2020; 39: 1059–61. doi: 10.1007/s10096-020-03913-9

Қосымша файлдар

Қосымша файлдар
Әрекет
1. JATS XML
Жүктеу
2. Fig. 1. The structure of the pathogens detected during the period from January 11, 2021, to August 31, 2022

Жүктеу (183KB)
Метадеректер
3. Fig. 2. The weekly detection of the pathogens of ARVIs, influenza, and COVID-19 during the period from January 11,2021 (the second week of 2021), to August 31, 2022 (the thirty-fifth week of 2022)

Жүктеу (425KB)
Метадеректер
4. Fig. 3. Comparison of detected cases of COVID-19 and positive cases of SARS-CoV-2 in individuals without symptoms of ARI over a week from January 11,21 (the second week of 2021) to August 31,2022 (the thirty-fifth week of 2022)

Жүктеу (605KB)
Метадеректер

© Bionika Media, 2023

Осы сайт cookie-файлдарды пайдаланады

Біздің сайтты пайдалануды жалғастыра отырып, сіз сайттың дұрыс жұмыс істеуін қамтамасыз ететін cookie файлдарын өңдеуге келісім бересіз.< / br>< / br>cookie файлдары туралы< / a>