Plasmacytoma as a secondary lesion in HIV infection. A clinical case of combined severe secondary diseases

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A case of solitary plasmacytoma with extensive lesions of the maxillofacial region in combination with a tuberculous process in a patient with HIV infection is presented. Antitumor therapy led to aggravation of immunodeficiency, which contributed to the development of tuberculosis with extensive drug resistance, a long course of the disease with an unfavorable prognosis.

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作者简介

Naylia Мikhaylova

Orenburg State Medical University, Ministry of Health of the Russian Federation

编辑信件的主要联系方式.
Email: n.mikhaylova@list.ru
ORCID iD: 0009-0006-7350-544X

Cand. Med. Sci., Associate Professor, Department of epidemiology and infectious diseases

俄罗斯联邦, Orenburg

Alekseу Mikhailovskу

Orenburg Regional Clinical Anti-Tuberculosis Dispensary

Email: michailovsky2007@yandex.ru
ORCID iD: 0000-0001-8995-9063

MD, Сhief Medical Officer

俄罗斯联邦, Orenburg

Oksana Plastamak

Orenburg Regional Clinical Anti-Tuberculosis Dispensary

Email: plastamak123@mail.ru
ORCID iD: 0009-0004-7181-8974

Head, «Orenburgsky» branch department № 1

俄罗斯联邦, Orenburg

Tatiana Kalinina

Orenburg State Medical University, Ministry of Health of the Russian Federation

Email: tkalinina31@gmail.com
ORCID iD: 0009-0001-2737-9634

Cand. Med. Sci., Associate Professor, Department of Epidemiology and Infectious Diseases

俄罗斯联邦, Orenburg

Natalya Skorovarova

Orenburg Regional Clinical Anti-Tuberculosis Dispensary

Email: nataliskor@mail.ru
ORCID iD: 0009-0000-1240-7957

Deputy Chief Physician for Treatment

俄罗斯联邦, Orenburg

Olga Nuriachmetova

Orenburg State Medical University, Ministry of Health of the Russian Federation

Email: knjazkinaolja@mail.ru
ORCID iD: 0009-0008-2147-5343

Cand. Med .Sci., Associate Professor, Department of Еpidemiology and Infectious Diseases

俄罗斯联邦, Orenburg

Tatiana Ermak

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: t.ermak@hiv-russia.ru
ORCID iD: 0000-0001-9490-7129

MD, Leading Research

俄罗斯联邦, Moscow

参考

  1. Feller L., White J., Wood N.H, Bouckaert M., Lemmer J., Raubenheimer E.J. Extramedullary myeloma in an HIVseropositive subject. Literature review and report of an unusual case. Head Face Med. 2009; 5(1). Article number 4. doi: 10.1186/1746-160X-5-4
  2. Pantanowitz L., Dezube B.J. Editorial comments. Multiple myeloma and HIV infection- causal or causal to incidence? AIDS Read. 2003, 13(8): 386–7.
  3. Pantanowitz L., Schlecht H.P., Dezube B.J. The growing problem of non-AIDS-defining malignancies in HIV. Curr. Opin. Oncol. 2006; 18: 469–78. doi: 10.1097/01.cco.0000239886.13537.ed
  4. Salarieh A., Rao C., Gottesman S.R.S., Alagha O., Todor R., Axiotis C.A. Plasma cell tumours in HIV-positive patients: report of a case and review of the literature. Leuk Lymphoma 2005, 46: 1067–74. doi: 10.1080/10428190500054566
  5. Лейгтон Р.А., Пивник А.В., Сергеева Е.П., Кремнева Н.В., Мухин О.В. Плазмоклеточные опухоли у ВИЧ-инфицированных пациентов (обзор литературы и собственные наблюдения). Клиническая онкогематология 2017; 10(4): 464–701. doi: 10.21320/2500-2139-2017-10-4-464-470 Leigton R.A., Pivnik A.V., Sergeeva E.P., Kremneva N.V., Mukhin O.V. [Plasma cell neoplasms in HIV-Infected Patients: A Literature Review and Case Series]. Clinical Оncohematology 2017; 10(4): 464–701. (In Russ.). doi: 10.21320/2500-2139-2017-10-4-464-470
  6. Фалалеева Н.А., Терехова А.Ю., Птушкин В.В., Османов Е.А., Поддубная И.В., Невольских А.А. и др. Солитарная (экстрамедулярная) плазмоцитома. Клинические рекомендации. Современная онкология 2020; 22(1): 7–15. doi: 10.26442/18151434.2020.1.200048 Falaleeva N.A., Terekhova A.Iu., Ptushkin V.V., Osmanov E.A., Poddubnaya I.V. et al. [Solitary (extramedullary) plasmocytoma. Clinical recommendations]. Journal of Modern Oncology 2020; 22(1): 7–15. (In Russ.). doi: 10.26442/18151434.2020.1.200048

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2. Fig. 1. HIV-infected patient with solitary plasmacytoma

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3. Fig. 2. The same patient at the end of the disease

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