ANTIBIOTIC RESISTANCE IN THE REAL PRACTICE OF AN INFECTIOLOGIST: RESULTS OF AN INVESTIGATION


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Objective. To analyze the antibiotic susceptibility of the microflora isolated in the bacteriological examination of smears from the upper respiratory tract of patients with acute respiratory diseases requiring hospitalization. Materials and methods. 935 upper respiratory tract specimens from children and 312 ones from adults admitted to the Center for Prevention and Control of AIDS and Infectious Diseases, Ministry of Health of the Kabardino-Balkar Republic, with acute respiratory diseases were analyzed. The EUCAST disk diffusion method (version 4.0, June 2014) was used to evaluate the antibiotic susceptibility of microorganisms. Results. The antibiotic susceptibility of St. aureus and St. epidermitidis, Streptococcus spp., Streptococcus pneumoniae, Streptococcus pyogenes, Neisseria spp, and Klebsiella pneumoniae was determined. There was the most pronounced resistance to antibiotics, primarily cephalosporins and macrolides, used for the hospital empirical therapy of acute respiratory infections. Cotrimoxazole may be currently used only to treat Pneumocystis pneumonia. Conclusion. Antibiotic resistance is about 2-fold higher in children than in adults. It is worth refusing erythromycin, azithromycin, and oxacillin when treating scarlet fever. Only stratification in the use of antibiotics will be able to reduce the resistance.

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作者简介

Marina IVANOVA

Email: marina19692003@list.ru
Center for Prevention and Control of AIDS and Infectious Diseases, Ministry of Health of the Kabardino-Balkar Republic Nalchik, Russia

M. KHAKUNOVA

Email: mkhakunova@list.ru
Center for Prevention and Control of AIDS and Infectious Diseases, Ministry of Health of the Kabardino-Balkar Republic Nalchik, Russia

N. KABLAKHOVA

Email: nataruslan@yandex.ru
Center for Prevention and Control of AIDS and Infectious Diseases, Ministry of Health of the Kabardino-Balkar Republic Nalchik, Russia

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