ANTIVIRAL THERAPY FOR FACIAL NEUROPATHY ASSOCIATED WITH HERPES SIMPLEX VIRUS TYPE 1


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Previous investigations have shown the value of herpes simplex virus 1 (HSV-1) in the development of nervous system lesions. Lesions of cranial nerves occur in patients of any age and substantially disrupt a patient’s ability to work and quality of life. Facial neuropathy (Bell’s palsy) is most common. This disease is characterized by the high rate of detection of HSV-1 markers and by the efficiency of antiviral therapy. However, the high prevalence of HSV-1 infection in the population, including also among healthy individuals cannot be viewed as convincing evidence for the role of the virus in the development of Bell’s palsy. The paper gives a clinical example of Bell’s palsy developing in a 27-year-old female patient with an exacerbation of HSV-1-induced infection. The treatment with anti-inflammatory and neurotropic drugs in combination with microcirculation-improving agents and non-drug therapy were ineffective. Lower-grade fever, facial asymmetry complaints, and headache persisted after a cycle of treatment. Blood tests showed lymphocytosis and the higher titers of IgM and IgG antibodies to HSV-1. The use of acyclovir resulted in the relief of symptoms.

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作者简介

Tatiana Ruzhentsova

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: ruzhencova@gmail.com
МD, Leading Researcher, Clinical Department of Infectious Pathology 3a, Novogireevskaya St., Moscow 111123, Russia

Daria Khavkina

«REAVIZ» Moscow Medical University

Email: havkina@gmail.com
Six-Year Student, Faculty of General Medicine

Pavel Chukhlyaev

«REAVIZ» Moscow Medical University

Email: pafachka@gmail.com
Six-Year Student, Faculty of General Medicine

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