Chromatographic determination of azodyes based on carbo- and heterocyclic alpha-dicarbonyl compounds

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Abstract

Over the last 20 years, liquid chromatography has become one of the most used methods for the investigation of natural and synthetic colorants in various objects. It is very important to control the content of azo dyes, based on phenanthrenequinone and hydrazine derivatives, which can potentially have a negative impact on human health. This article is devoted to the possibility of chromatographic separation of some azo dyes based on carbo- and heterocyclic alpha-dicarbonyl compounds. Optimal conditions for the analysis (solvents, eluent and its flow rate, temperature, wavelength) are selected; detection limits and linear ranges of determination of the studied compounds are established.

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About the authors

Igor Anatolievich Filenko

Russian Institute for Scientific and Technical Information (VINITI RAS)

Author for correspondence.
Email: chemistf@mail.ru
ORCID iD: 0000-0002-4204-295X

Ph.D., Senior Researcher at the Department of Scientific Information on Chemistry and Chemical Technology of the Department of Scientific Information on Chemistry and Materials Sciences 

Russian Federation, Moscow

Olga Nikolaevna Bubelo

the All-Russian Institute of Scientific and Technical Information of the Russian Academy of Sciences (VINITI RAS)

Email: bon199@yandex.ru

Ph.D., Head of the Department of scientific information on problems of chemistry and material sciences of the department of scientific information on problems of chemistry and material sciences 

Russian Federation, Moscow

Svetlana Sergeevna Bozhenkova

A. N. Kosygin Russian State University (Technology. Design. Art)

Email: bozhenkova_ss@mail.ru

postgraduate student 

Russian Federation, Moscow

Nadezhda Aleksandrovna Polyanskaya

A. N. Kosygin Russian State University (Technology. Design. Art); Peoples’ Friendship University of Russia (PFUR)

Email: polyanskaya_na@pfur.ru

PhD in Chemistry, Associate Professor, Department of General and Inorganic Chemistry

Russian Federation, Moscow; Moscow

Olga Vladimirovna Kovalchukova

A. N. Kosygin Russian State University (Technology. Design. Art); Peoples’ Friendship University of Russia (PFUR)

Email: kovalchukova-ov@rudn.ru

Doctor of Chemical Sciences, Head of the Department of Inorganic and Analytical Chemistry (RSU), Professor of the Department of General Chemistry (PFUR)

Russian Federation, Moscow; Moscow

References

Supplementary files

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1. JATS XML
2. Fig. 1. Calibration dependence of concentration (C) on the peak area of HL3

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3. Fig. 2. Chromatogram of a mixture of dyes at 464 nm (concentration 1.0 mg dm−3), where peaks 1, 2, 3, 4 are HL5, HL6, HL1, HL3, respectively, on a 200 mm column

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4. Table 1a

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5. Table 2

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6. Table 3

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7. Table 4

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8. Table 5

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9. Table 6

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10. Table 7

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Copyright (c) 2025 Filenko I.A., Bubelo O.N., Bozhenkova S.S., Polyanskaya N.A., Kovalchukova O.V.