Modern Approaches to Measuring the Mass Concentration of 1,1-Dimethylhydrazine in Water Using Chromatographic Methods

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Abstract

This review discusses the advantages and disadvantages of chromatographic approaches proposed in the scientific literature for the determination of J,JPdimethylhydrazine QUDMHS in water with the aim of providing information that can be useful in the development of highly sensitive methods for measuring the mass concentration of UDMH in water bodies at levels corresponding to current hygienic standards. The use of methods of highPperformance liquid chromatography _ tandem mass spectrometry with prePcolumn derivatization of the analyte can be considered promising. There are few official methods for quantitative determination of NDMH in aqueous samples that
meet the necessary metrological requirements.

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About the authors

Elena P. Vekhter

FSUE Research Institute of Hygiene, Toxicology and Occupational Pathology of FMBA of Russia

Author for correspondence.
Email: vekhter@rihtop.ru

Head of the Laboratory of Chemical and Analytical Research

Russian Federation, Volgograd

Irina K. Gorkina

FSUE Research Institute of Hygiene, Toxicology and Occupational Pathology of FMBA of Russia

Email: gorkina@rihtop.ru
ORCID iD: 0000-0002-6391-3785

Head of the Laboratory of Sanitary and Chemical Measurements

Russian Federation, Volgograd

Olga N. Novikova

FSUE Research Institute of Hygiene, Toxicology and Occupational Pathology of FMBA of Russia

Email: novikova@rihtop.ru
ORCID iD: 0000-0002-9753-1881

Candidate of Medical Sciences, Deputy Director

Russian Federation, Volgograd

Valery A. Antonov

FSUE Research Institute of Hygiene, Toxicology and Occupational Pathology of FMBA of Russia

Email: antonov@rihtop.ru
ORCID iD: 0000-0001-6435-4316

Doctor of Medical Sciences, Professor, Acting Director

Russian Federation, Volgograd

Inna K. Zhurkovich

FGBU S. N. Golikov Scientific-Clinical Centre of Toxicology of the FMBA of Russia

Email: zhurkovich.i.k@toxicology.ru
ORCID iD: 0000-0002-9885-6055

Candidate of Chemical Sciences, Leading Researcher and Acting Head of the Laboratory of Toxicological Chemistry of Organic Compounds

Russian Federation, St. Petersburg

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Copyright (c) 2024 Vekhter E.P., Gorkina I.K., Novikova O.N., Antonov V.A., Zhurkovich I.K.

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