Study of a Wide Class of Organic Compounds by Chromatograph Mass Spectrometry

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Abstract

Chromatography-mass spectrometry is an analytical method based on a combination of the capabilities of chromatography for the separation of substances and mass spectrometry, which uses their spectral characteristics for the qualitative and quantitative determination of individual components in complex mixtures. A brief historical background on the development of mass spectrometry, the types of main components of the mass spectrometer and a description of the operation of the chromatographymass spectrometer using the example of the Kristallux‑4000M-Maestro-αMS device, as well as its technical characteristics are provided. The applications of the gas chromatography-mass spectrometer and some specific measurement techniques are listed.

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About the authors

Alexander V. Astakhov

Meta-Chrome Research and Production Company

Author for correspondence.
Email: Astahov-AV@meta-chrom.ru

Deputy Director for Science

Russian Federation, Yoshkar-Ola

References

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  2. Yashin Ya. I. Yashin E. Ya. Yashin A. Ya. Gas chromatography. M., TransLit. 2009, 528 p. (in Russ.).
  3. Lebedev A. T. Mass spectrometry in organic chemistry. M. Beanom publ., 2003, 493 p. (in Russ.).
  4. Polishchuk V. R. How to see a molecule. M., Himiya publ. 1979, 384 p. (in Russ.).
  5. Shapovalova E. N., Pirogov A. V. Chromatographic methods of analysis. Methodological manual for a special course. M.: MSU publ., 2007, 204 p. (in Russ.).

Supplementary files

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2. Fig. 1. Block diagram of the chromatography-mass spectrometer

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3. Fig. 2. Crystallux-4000M - Maestro-αMS chromatography-mass spectrometer

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