Chronic tonsillitis. The role of probiotics in the treatment of inflammation

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Abstract

The problem of treatment of chronic tonsillitis is always relevant. The disruption of the protective mechanisms of palatal tonsils, pharyngeal mucosa and other immunocompetent organs contributes to the chronicity and exacerbation of inflammation. Tonsillectomy and antibacterial treatment involves the removal of palatal tonsils damaged by inflammation and alteration of microflora, but also reduces or suppresses the protective functions of the associated tissues. There are various initial etiopathogenetic factors of chronic inflammation of palatine tonsils, but the main one is persistent pharyngeal dysbiosis, which hinders the resolution of inflammation. Therefore, cleaning of the palatal tonsils should be supplemented by creating conditions for local and systematic restoration of the microbiocenosis. However, this issue is often overlooked and treatments to stabilize the microflora are not prescribed during antibiotic therapy. In recent years, several studies have evaluated the association between gastrointestinal disorders and palatal tonsil inflammation. Based on the general literature on intestinal disorders, microbiota and immunity, it was concluded that there may be direct correlation between the disruption of the protective functions of the intestine and palatal tonsils in patients with chronic tonsillitis with inflammatory and functional intestinal disorders, especially with intestinal dysbiosis.

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About the authors

Galina V. Lavrenova

Academician I.P. Pavlov First St. Petersburg State Medical University

Email: lavrenovagv@yandex.ru
ORCID iD: 0000-0002-3537-0226
SPIN-code: 2440-5103

MD, Dr. Sci. (Medicine)

Russian Federation, Saint Petersburg

Kristina Ts. Zhamakochyan

Academician I.P. Pavlov First St. Petersburg State Medical University

Author for correspondence.
Email: kristina.voita@mail.ru
ORCID iD: 0000-0003-3120-4906
Russian Federation, Saint Petersburg

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