Vol 16, No 1-2 (2016)

Articles
THE INDICATORS OF BIOCHEMICAL AND ACID-BASED COMPONENTS IN BLOOD OF PREGNANT WOMEN SUFFERNING FROM ECLAMPSIA ASSOCIATED WITH CHRONIC KIDNEY DISEASE
BALTER R.B., MANSUR HASSAN S.H.
Abstract
The article studies the findings of the biochemical and acid-base composition of the blood of pregnant women with pre-eclampsia, associated with chronic kidney disease. Preeclampsia is considered one of the most dangerous complications of pregnancy. The most severe form of preeclampsia developing in association with extragenital pathology, one of which is chronic kidney disease. The study of biochemical parameters which reflect the severity of multiple organ failure in pre-eclampsia are of particular importance. They contribute to the choice of infusional and systemic therapy.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):7-12
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IMMUNOHISTOCHEMICAL FEATURES OF THE ENDOMETRIUMIN WOMEN WITH TUBAL-PERITONEAL INFERTILITY
VASYUHINA A.A., TSELKOVICH L.S.
Abstract
The paper deals with the results of histological and immunohistochemical study of the endometrium in women with tubal-peritoneal infertility. According to studies the majority of women with tubal-peritoneal infertility suffered from some form of chronic endometritis. Only complete examination of women with tubal-peritoneal infertility including immunocytochemical and histological study of the endometrium is necessary for successful IVF.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):13-16
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PREDICTION MODEL IN OPTIMAL COUNSELING ON CHANCESOF A PREGNANCY AFTER IN VITRO FERTILIZATION
ZAZULINA Y.A.
Abstract
A total of 318 couples undergoing IVF were observed. The multinomial logistic regression model was specified for global process. The main outcome measures were: ongoing pregnancy, miscarriage before and after 12 weeks gestation, live birth. The significant explanatory variables for global process were female age (odds ratio 1,064), previous live births (odds ratio 0,488), diminished ovarian reserve (odds ratio 2,589).
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):17-20
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EFFECTIVNESS OF THE THERAPY OF PATIENTSWITH OVARIAN ENDOMETRIOTIC CYSTS
KALINKINA O.B., TEZIKOV Y.V., TEZIKOVA T.A., LIPATOV I.S., KRUKOVA G.A., ARAVINA O.R.
Abstract
The aim of this study was to evaluate the impact of post-operative dienogest (visanna) managment in dosage of 2 mg continiously on the rate of recurrence after laparoscopic excision of ovarian endometrioma. For this purpose we introduced a ‘post-operative dienogest recommendation’ for patients treated with laparoscopic excision of endometrioma and not seeking pregnancy. The endometrioma recurrence rate and clinical signs and severity were evaluated at 3 and 6 moths of post operative follow-up. This research showed effectiveness of the usage of dienogest in order to prevent post-operative recurrence of endometiotic cysts.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):21-26
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EFFICIENCY OF COMPLEX INTENSIVE CARE AND PREGNANCY OUTCOMES ОF WOMEN WITH PREECLAMPSIA ASSOCIATED WITH CHRONIC KIDNEY DISEASE
MANSUR HASSAN S.H.
Abstract
The article presents the results of the response to treatment of women with preeclampsia associated with chronic kidney disease. We have analyzed the outcomes of intensive treatment of severe preeclampsia in women with chronic kidney disease who live in Sudan.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):27-32
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THE RATIONALE FOR THE TACTICS OF YOUNG NULLIPAROUS WOMEN WITH CERVICAL PATHOLOGY ASSOCIATED WITH HPV WITH ACCOUNT OF IMMUNOCYTOCHEMICAL PARAMETERS
NIKULINA I.E., IVANOVA T.V.
Abstract
Young nulliparous women within flammatoryuterine cervix diseaseassociated with HPV, are recommended complexanti-inflammatorytherapy, includingspecificantiviral treatment. In the presence of CIN I, revealed by liquidcytology, and lack ofimmunocytochemicalmarkers the destruction of the uterine cervixcan be delayedor denied. Treatment can be limited tospecific antiviraltherapy.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):33-36
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COMPARISON OF PREDICTIVE CAPABILITYOF CYTOMORPHOLOGICAL AND CRYSTALLOGRAPHIC METHODSOF BREAST SECRET ASSESSMENT IN WOMEN OF HIGH RISK FOR EARLY HYPOGALACTIA
PRIKHODKO A.V., TEZIKOV Y.V., LIPATOV I.S.
Abstract
The article is devoted to the assessment of the prognostic significance of the morphological and crystallographic methods for studying mammary glands secretion in postpartum women with a history of placental insufficiency pregnancy to select the most informative and timely improvement of this pathology. The early detection of hypogalactia in 210 postpartum women with placental insufficiency of varying severity during gestation was performed by determining morphological type of mammary glands secretion smear and crystallographic method. To calculate the sensitivity, specificity, positive and negative predictive value, the diagnostic accuracy of methods of early lactational disorders within the first 7 days of postpartum period we investigated subjective and objective clinical hypogalactia signs in the mother and the child, determined the amount of milk by gravimetric method, additionally measured the temperature in the armpit and lower quadrant of the left breast. Results of the study showed cytomorphological and crystallographic techniques to be comparable, but crystallography has the advantage and the detection rate of early hypogalactia and ease of use. This method has the highest predictive value (Se 99,3%, Sp 97,2%, P 98,4%) for the early hypogalactia compared with another studied method.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):37-43
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ACUTE KIDNEY INJURY IN PREMATURE INFANTS:CLINICAL SIGNIFICANCE, DEVELOPMENT, THE POSSIBILITYOF EARLY DIAGNOSIS
ABORIN S.V.
Abstract
Acute kidney injury is one of the most prevalent pathologies of urinary tract in premature infants, affected by an acute hypoxic in perinatal period. AKI is an independent risk factor for poor outcomes in severely ill neonates. In neonatal period, importance and dilemmas of AKI are even more pronounced, as a newborn’s kidneys are more susceptible to hypoperfusion and have low glomerular filtration rate, high renal vascular resistance, high plasma rennin activity, decreased intercortical perfusion, and decreased reabsorbing of sodium in the proximal tubules.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):44-49
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RHEUMATOLOGY: MODERN ASPECTS OF PATHOGENESISAND PHARMACOTHERAPY OF JUVENILE IDIOPATHIC ARTHRITIS, STRATEGIC PATHWAYS
KAGANOVA T.I., SHEVYREV D.V.
Abstract
The review summarizes modern aspects of the pathogenesis of rheumatic diseases including JIA. The functional role of IL17, IL21, Th17-cells is demonstrated. The importance of intracellular signal transducers of cytokines Jak/STAT and Smad in the development of autoimmune disease is discussed. Promising directions of pharmacotherapy of rheumatoid diseases is described.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):50-55
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PREDICTING THE RISKS OF MANIFESTATION OF CMV-INFECTIONIN TRANSPLANTATION OF THE ALLOGENEIC KIDNEY ON THE BASIS OF MATHEMATICAL MODELINGOF THE RECIPIENTS’S IMMUNE SYSTEM
AVDEEVA A.A., BOGUSH V.V., PARABINA E.V.
Abstract
The article is devoted to the development of a mathematical model of the immune system of transplant recipients to predict risk of manifestation of CMV infection in the early and intermediate postoperative periods after allogeneic kidneys grafting. A working mathematical model for a specific recipient allows to make a decision about increasing the frequency of laboratory tests to identify CMV infection. In the presence of HLA-a antigens/alleles of genes associated with high risk of developing CMV infection it allows to perform preventive antiviral therapy.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):56-60
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A SYSTEMATIC APPROACH TO THE ASSESSMENT OF SEVERITYAND PROGNOSIS OF THE DUST-INDUCED LUNG DISEASES COURSE
BUDASH D.S.
Abstract
The article is devoted to the improvement of early diagnosis quality in dust-induced lung diseases, their development is associated with exposure to dust aerosols of varying degrees of fibrogenesis. The determination of the characteristics of dust-induced lung diseases (atrophic process descending, cytokine profile peculiarities, a significant number of hypercytokinemia cytokines) to allow to estimate the origin, course and progression of dust-induced lung diseases. It will improve the quality of early diagnosis, help to optimize strategies of primary and secondary disease prevention, predict the disease course, and reduce the number of disabling forms.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):61-67
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RISK FACTORS AS PREDICTORS OF BONE MINERAL DENSITY DECREASE AT SENIOR AGE GROUPS PATIENTS WITH ЕНЗУ 2 DIABETES MELLITUS
BULGAKOVA S.V., SHAFIEVA I.A., KUDLAY D.A.
Abstract
This study is devoted to a possibility of use of risk factors as predictors of decrease in bone mineral density in elderly patients with type 2 diabetes. The found interrelations of bone mineral density and the studied risk factors allow to decide on medical strategy of management of postmenopausal women with type 2 diabetes, taking into consideration anamnestic and anthropometrical data.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):68-74
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СOMPARATIVE ANALYSIS OF THE RELATIONSHIP OF CLINICAL AND LABORATORY DATA WITH THE OUTCOME OF SEPSIS IN ICU
KEZKO J.L., LUNINA A.V., GUSYAKOVA O.A., TRUKHANOVA I.G.
Abstract
Objective. The study aims to analyze the dynamic relationship of clinical and laboratory data of patients with sepsis and the outcome in an intensive care unit. Materials and methods. A retrospective analysis of 108 case histories of patients with sepsis was made. The average age of patients was 50,5 ± 15,5 (maximum 77 y.o., minimum 21 y.o.). Men accounted for 58% of all incoming patients. 29 patients were in the state of septic shock. On admission the state of 69 patients resulted from abdominal surgical pathology, 25 suffered from severe soft tissue infection, 10 patients had nosocomial pneumonia, 4 patients had angiogenic catheter infection. Relative mortality rate was 32.4%. Criteria included into the integrated severity scales SOFA and SAPS II were studied. Taking into consideration the current studies [10-12, 45-53] the importance of the following laboratory parameters - the rate of lymphocytes, thromboelastography index and Pct level were investigated. Results. The multiple regression analysis in the common group and the group of survived patients with sepsis taking into account the dependent variable of the disease outcome in the ICU and the hospital bed-day in the ICU showed early significant changes in hemostasis which required timely correction. Нypercoagulable syndrome, thrombocytopenia initiation, activation of secondary fibrinolysis are characteristic of the survived patients. Hyperfibrinolysis with the normo- and hypocoagulation syndrome, progressive thrombocytopenia are observed in the common group of patients. Conclusion. Nonspecific clinical symptoms of sepsis necessitate the choice of early laboratory sepsis markers in order to initiate the timely targeted therapy. Dynamics of hemostasis, identified by thromboelastography is the early predictor of sepsis. They characterize the worsening thrombinemia. Valid additional criteria of unfavorable sepsis outcome in order of importance were the percentage of lymphocytes, leukocytosis and procalcitonin levels.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):75-81
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EFFECT OF ANTIVIRAL THERAPY AND THE GENOTYPE OF THE VIRUS ON THE EXTE OF FATTY HEPATOSIS IN PATIENTS WITH CHRONIC HEPATITIS C ACCOMPANIED BY LIPIDIC DISTRESS SYNDROME
KONSTANTINOV D.Y.
Abstract
The article is devoted to modern views on the development of fatty hepatosis in patients with chronic hepatitis С associated with lipidic distress syndrome. The analysis of the effect of antiviral therapy on the level of fatty hepatic infiltration depending upon the genotype of the virus in patients with chronic hepatitis С is performed. Received findings revealed the degree of severity of fatty hepatosis not to depend on the genotype of the virus. Antiviral therapy reduces the severity of fatty infiltration of the liver in case of genotype 3a in patients with chronic hepatitis and lipidic distress syndrome.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):82-86
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DAILY BLOOD PRESSURE PROFILE AND DYNAMICS OF COGNITIVE IMPAIRMENT AT PATIENTS WITH THE ARTERIAL HYPERTENSION WITHIN THE FIRST YEAR AFTER THE BRAIN STROKE
LOPINA E.A., LIBIS R.A.
Abstract
Article is devoted to modern problems of post-stroke patients with hypertension. For this purpose the analysis of the daily analysis of BP and dynamics of cognitive violations were performed. The views of the most famous scientists of our time in the field, and also the results and conclusions of our own research are presented in the article. Our findings confirm the hypotensive therapy aimed at the recovery of SBP in the range of 125-134 mm Hg to improve patients’ cognitive functions and life quality.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):87-93
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CHRONIC MYELOID LEUKEMIA: PROBLEMS AND PROSPECTS (LITERATURE REVIEW)
NAUMOVA K.V., KRIVOVA S.P., ZOLOTOVSKAY I.A., STEPANOVA T.Y.
Abstract
The article is devoted to the review of the history and the current concept of pathogenesis, clinical picture and treatment of chronic myeloid leukemia. Literature reviews show endothelial dysfunction to be a risk factor for the development of cardiovascular diseases. In this article the pathogenesis of development of endothelial dysfunction is described. The problems of endothelial dysfunction diagnostics in patients with chronic myeloid leukemia are covered.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):94-99
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VIOLATION OF EVERYDAY FUNCTIONAL ACTIVITY IN ELDERLY PATIENTS WITH COMBINED ISCHEMIC HEART DISEASE AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE
OVCHINNIKOVA E.A.
Abstract
The article assesses the state of coagulation and fibrinolysis system in a combined course of ischemic heart disease and chronic obstructive pulmonary disease in elderly patients. The effect of the disease progression on the reduction of the patients’ physical activity is studied.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):100-107
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CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD): CLINICAL AND IMMUNOLOGICAL EFFECTS OF VACCINATION AGAINST RESPIRATORY INFECTIONS
PROTASOV A.D.
Abstract
About 30% of COPD exacerbations are due to viral infections, and influenza A and B viruses are among the most common causes. The aim of the study is to assess the exacerbation rate, the number of courses of antibiotic chemotherapy, and immunological effects of mono vaccination with a new immunoadjuvant influenza vaccines vs. combined vaccination against pneumococcal infection, Haemophilus type b infection, and influenza in COPD patients. Both complex vaccination against S. pneumoniae, H. influenzae type b, and influenza and mono vaccination with a new immunoadjuvant influenza vaccine lead to statistically significant reduction in the number of COPD exacerbations and the number of courses of antibiotic chemotherapeutic agents. The study represents the immunogenicity of the new influenza immunoadjuvant vaccine administered as monovaccine to COPD patients in accordance with СРМР requirements.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):108-115
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THE STATE OF ENDOTHELIUM IN ELDERLY PATIENTS WITH CHRONIC KIDNEY DISREASE
ROMASHEVA E.P., BULGAKOVA S.V., TRETYAKOVA A.R., BOGUSH V.V., KUDLAY D.A.
Abstract
The article is devoted to the study of endothelial function and microcirculation in elderly patients with chronic kidney disease. The results of authors’ investigations and conclusions are presented, endothelial dysfunction is emphasized. Authors’ findings confirmed the positive effect of hemodialysis on microcirculation in elderly patients with stage 5 chronic kidney disease.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):116-119
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QUALITY OF LIFE IN PATIENTS WITH CHRONIC MYELOID LEUKEMIA DURING TREATMENT WITH TYROSINE KINASE INHIBITORS I AND II GENERATIONS (REVIEW)
FEDOROVA E.J., NAUMOVA K.V., KRIVOVA S.P., STEPANOVA T.Y.
Abstract
The article is devoted to the up-to-date presentations of chronic myeloid leukemia and methods of treatment. At present, in addition to assessment of the response to therapy, the examination of patients health status is actual . These are the quality of life and the symptom intensity, depending on the treatment outcomes and the age groups. The particular attention is drawn to the quality of life of the CML patients taking tyrosine kinase inhibitors of the first and second generations.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):120-125
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STENTING IN POST PAPILLOTOMY ANASTOMOSIS IN RESTENOSIS
ABJALOV M.A.
Abstract
The article is devoted to endoscopic treatment of postpapillotomy anastomosis in restenosis. Authors compared long-term results of efficacy and sa-fety of endoscopic sphincterotomy, ballon dilatation and long-term multi-stent placement in the study group.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):126-129
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ABOUT THE POSSIBILITY OF METASTATIC THYROID LESIONS IN KIDNEY CANCER
ARISTARKHOVA A.A.
Abstract
The article is devoted to modern views on the frequency, the preconditions, the characteristics of the course, the difficulties of early diagnosis and treatment of metastatic thyroid lesions in kidney cancer. The impact of metabolic changes in the tissues of the thyroid gland in various diseases on the incidence of this disease is analyzed. Difficulty in clinical diagnosis of metastasis of clear cell kidney cancer in the thyroid gland is emphasized. The data of 9 observations of clear cell kidney cancer metastasis in the thyroid gland identified in Ryazan City Clinical Hospital № 11 are presented in the article. It is necessary to take into account the medical history data of the patient, characteristic ultrasound findings, cytological findings and the possibility of clinical manifestations of thyroid metastasis in the late postoperative period. Surgical treatment is the method of choice in case of metastatic lesions of the thyroid gland.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):130-132
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UROLOGICAL COMPLICATIONS OF HIFU FOR PROSTATE CANCER: INTERNATIONAL AND DOMESTIC EXPERIENCE
GUBANOV E.S., BORYAEV E.A., ZIMICHEV A.A.
Abstract
High-Intensity Focused Ultrasound (HIFU) is an alternative choice in localized and low-or-medium-risk prostate cancer treatment. Our review reported about side effects and urological complications of HIFU: urinary incontinence, urethral stricture, rectourethral fistula, erectile function impairment.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):133-138
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SURGICAL TACTICS ON NUMEROUS RELAPOROTOMY ON PATIENTS WITH GENERAL PURULENT PERITONITIS
ZEMLYAKOV D.S., ARUTUNYAN A.G., GOLBRACH V.A.
Abstract
Of the total 495 patients diagnosed with generalized purulent peritonitis were enrolled in the study, 160 patients underwent elective relaporotomy. The patients were stratified into those having a high or low risk of developing intra-abdominal purulent complications. Relaporotomy was indicated if the risk of developing intra-abdominal purulent complications was high. Based on the severity stratification score, the patients were divided into three groups of those having low (0-8 score), high (9-15 score) and extremely high (16-18 score) risk of developing intra-abdominal purulent complications. The use of severity stratification score resulted in a 13,2% reduction in mortality in patients who had elective relaporotomy compared with 38,7% of deaths in patients who underwent emergency relaporotomy.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):139-144
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ANALYSIS OF REMOTE TREATMENT RESULTS OF PATIENTS WITH DIFFUSE TOXIC GOITER
KVASOV V.V.
Abstract
In this article, the authors analyzed long-term outcomes of 428 patients with Graves disease. The main causes determining thyroid status of patients after surgery in the nearest and remote periods of observation were found out. The evolution of the operated patients’ status depending on the extent of surgery and the duration of observation is presented. Conclusions were done on the basis of the analysis.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):145-148
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RADIOFREQUENCY ABLATION FOR METASTATIC LUNG LESIONS
KOROLEV D.G.
Abstract
Metastatic lung lesions remain the “issue of the day”. The frequency of lung metastases according to different authors vary from 1.6 to 55.4% depending on the localization and histological structure of the primary tumor. The objective of this study was to evaluate the effectiveness of radiofrequency ablation in patients with lung metastases. 317 radiofrequency ablations were performed in 170 patients with lung metastases. The effect of primary tumor localization and the amount of metastasis on overall survival was investigated.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):149-152
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PRESERVING THE NIPPLE - AREOLA COMPLEX PATIENTS WITH BREAST CANCER
KOCHETKOV R.I., KOZLOV S.V., KAGANOV O.I., TKACHEV M.V.
Abstract
The article reflects the experience of the reconstructive and plastic surgery at the premises of Samara Regional Clinical Oncological Center. This method allows to preservt the nipple-areola complex in patients with breast cancer.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):153-155
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EFFECT OF THE PROGRAMMED ASPIRATION AND IRRIGATION REHABILITATION ON TOXIC SYNDROME PARAMETERS IN PATIENTS WITH SUPPURATIVE NECROTIC COMPLICATIONS OF DIABETIC FOOT SYNDROME
SERGEEV V.A., GLUKHOV A.A.
Abstract
The purpose of the study was to improve the treatment results for patients with suppurative necrotic complications of diabetic foot syndrome (DFS) without critical ischemia by using the programmed aspiration and irrigation rehabilitation (PAIR) method. The patients with DFS were divided into two groups depending on the way of postoperative rehabilitation of the suppurative focus after radical surgery. In the reference group, rehabilitation was carried out according to conventional techniques. In the study group, the combined treatment was supplemented with a new method of PAIR using the original equipment AMP-01. The results of the performed investigations confirmed the efficiency of the PAIR method, the use of which provided normalization of laboratory findings in the study group at an earlier date than in the reference group. This has contributed to an earlier relief of inflammation in the suppurative focus and to the transition from the inflammatory to the proliferative phase of the wound healing, as well as to reduction of the time of treatment and rehabilitation in this group of patients.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):156-163
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PERFORMING OF RECONSTRUCTIVE SURGERY IN BREAST CANCER PATIENTS IN SAMARA REGIONAL CLINICAL ONCOLOGICAL CENTER
TKACHEV M.V., KOZLOV S.V., KAGANOV O.I., KOCHETKOV R.I.
Abstract
The article describes the experience of reconstructive and plastic surgery carried out in Samara Regional Clinical Oncological Center. They allow to preserve the nipple-areola complex in patients with breast cancer.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):164-166
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RESULTS OF ANTIREFLUX SURGICAL CORRECTION OF HIATAL HERNIAS IN ELDERLY PATIENTS
KHUBOLOV A.M., TOLSTOKOROV A.S., KOVALENKO Y.V.
Abstract
Objective. The specific features of disease course and results of surgical corrections of hiatal hernias, and analyses of possibly most effective method of choice in elderly people are analyzed. Methods. 49 cases of hiatal hernias surgical corrections were analyzed. Patients average age was - 66, 7 ± 4,2. Results. We found out that tension-free methods of laparoscopic plastics of giant hiatal hernias did not result in lower complications rate in postoperative period or higher level of quality of life. Conclusions. We found no statistically significant evidence of higher efficacy of tension-free surgical corrections in comparison to traditional method of Nissen, in cases of surgical treatment of elderly people with hiatal hernias (frequency of functional complications, rate of recurrent hernias, quality of life were analyzed).
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):167-171
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СEREBRAL BLOOD FLOW OCCLUSION WHEN PERFORMING THROMBECTOMY IN PATIENTS WITH ACUTE ISCHEMIC STROKE
VOLODYUKHIN M.Y.
Abstract
This paper presents a comparative analysis of the efficiency of the establishment of cerebral blood flow in trombectomy using stent retriver on the background of the blockade of cerebral blood flow with the use of occlusive guiding catheter and without blockade of cerebral blood flow. 22 patients with acute ischemic stroke in the middle cerebral artery were operated on.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):172-175
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AUTONOMIC REGULATION AND PARAMETERS OF CARDIOVASCULAR ACTIVITY INDER PENITENTIARY STRESS
DYUZHEVA E.V., PONOMAREV S.B., POPOVA N.M.
Abstract
The article presents the main indicators of the cardiac rhythm autonomic regulation and the functional state of the cardiovascular system in prisoners exposed to a prolonged prison stress. Authentically the study revealed the high rates of arterial pressure in persons with lower uneasiness and a longer period of imprisonment to be presumably caused by a decrease of sympathetic activity of cardiac rhythm autonomic regulation and dulled baroreflex response.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):176-181
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GENETIC MARKERS CIMBINED WITH CLINICAL AND LABORATORY PARAMETERS ON THE PROGNOSIS OF COMPLICATIONS AFTER PERCUTANEOUS CORONARY INTERVENTION IN PATIENTS WITH ST-ELEVATION ACUTE CORONARY SYNDROME
KRUGLOV V.N., RUBANENKO A.O.
Abstract
Aim: the aim of the study is to investigate the effect of genetic variants combined with clinical and laboratory parameters on the prognosis of complications after PCI in patients with ST-elevation and acute coronary syndrome. Material and methods. 171 patients, consequently hospitalized with ST-elevation ACS from 15.08.2011 to 02.11.2014 were observed. Patients with the recurrence of coronary insufficiency after PCI formed the group I (n = 43, 38 male patients, 88.4 %, average age 56.7 ± 10.2). Recurrent coronary angiography revealed stent restenosis of the infarct-related artery and repeated stenting was performed. Group II consisted of 128 patients (103 males, 80.5%) with an uncomplicated postoperative period, average age 56,3 ± 10,8). The results of genetic study by 7 polymorphic genetic variants, coronary angiography data, ECG, laboratory findings were analyzed. The results. Groups significantly differed in outcomes of PCI: recurrence of myocardial infarction was 9,3% and 0%, resp. (p=0,004), frequency of myocardial reinfarction was 21,0% and 0%, resp.(p<0,0001). The combination of alleles (4G/4G) of gene PAI-I + (G455A) of gene FI + (Т1565С) of gene I GPIII was defected in 9 patients (21,0%) of the group I and it was detected in 11 patients (8,6%) of group II when analized, resp.(p=0,03). The combination of alleles (G455A) of gene FI + (Т1565С) of gene I GPIII was detected in 10 patients (23,3%) of group I, this combination was met in 15 patients (11,7%) of group II. The combination of alleles (4G/4G) of gene PAI-I + (G455A) of gene FI + (Т1565С) of gene I GPIII + (G10976A) of gene VII was observed in 4 patients (9,3%) of group I and it was observed in 1 patient (0,8%) of group II, resp.(p=0,01). The combination of alleles (G455A) of gene FI + (Т1565С) of gene I GPIII + (G10976A) of gene VII was detected in 4 patients (9,3%) of group I and it was detected in 2 patients (1,6%) of group II, resp.(p=0,04). Conclusion. The combinations of genetic polymorphisms FI + PAI-I + GPIII, PAI-I + FI + GPIII + FVII, FI + GPIII, F1+ GPIII +FVII and FI + GPIII + FVII are associated with restenosis of stented infarct-related artery.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):182-189
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IMPLICATION OF ADIPOKINES IN THE CASCADE OF INFLAMMATORY AND METABOLIC REACTIONS IN THE DYNAMICS OF ST ELEVATION MYOCARDIAL INFARCTION
MATEESKU K.A., LEBEDEV P.A., SCHERBAKOVA N.F.
Abstract
Acute myocardial infarction is a condition associated with a complex of haemodynamic, inflammatory and metabolic sequelae. In 65 males the pathogenic role of leptin, resistin, adiponectine was investigated in acute myocardial infarction and early recovery period. Studies revealed the dynamic changes of adipokines in acute myocardial infarction. These adipokines are involved in postinfarction inflammation and contribute to insulin resistance. The imbalance of adipokines causes decrease of patients’ life quality. Authors revealed positive effect of adiponectin on the body composition parameters according to bioimpedance.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):190-195
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THE DYNAMICS OF CARDIOINTERVALOGRAPHY INDICATORS IN DIFFERENT PERIODS OF CEREBRAL CONCUSSION
MELNIKOV K.N.
Abstract
Traumatic brain injury is a current problem. Research objective is to improve the diagnostics of a slight craniocerebral injury by means of heart rate variability investigation in order to objektivize of vegetative disorders. Materials and methods: 120 patients with cerebral concussion were studied. They underwent cardiointervalography in the acute period of the trauma and the dynamics of their state was investigated. Results: the obtained data allow to draw a conclusion that the cardiointervalography helps to reveal vegetative dysfunction at a slight craniocerebral injury and the recovery of the vegetative status on the treatment.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):196-199
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CARDIAC ACTIVITY AND BODY COMPOSITION OF ADOLESCENT ATHLETES WITH DIFFERENT TIME LOADING
KHARISOVA E.Z.
Abstract
The article is devoted to the assessment of physiological indicators of cardiac activity and body composition of adolescent athletes. The possibilities of 3D testing with Esteck System Complex Systems (Multiscan Wellness - Oxi) are investigated. It was established that four hour weekly training load difference affects only cardiac parameters, namely heart rate and stroke volume. No significant changes are observed in the body structure.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):200-206
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MORPHOLOGICAL PROFILE OF CORNEOSCLERAL ACCESS IN CATARACT SURGERY
GORBUNOV A.E., MALOV V.M., EROSHEVSKAYA E.B., MALOV I.V.
Abstract
Cataract surgery involves lensectomy via a small self-sealing incision access. The incision contour is responsible for the result of the operation. The article presents findings of the morphological profile of the corneoscleral and corneal access by means of optical coherence tomography.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):207-211
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IMPROVEMENT OF THE EFFECTIVENESS OF THE UPPER LATERAL TEETH MOVEMENT IN PATIENTS WITH DISTAL OCCLUSION
DIKOVA A.A.
Abstract
The article is devoted to the time of orthodontic treatment reduction of in patients with distal occlusion. The article highlights the most frequently used orthodontic appliances in the teeth distalization, identifies their advantages and disadvantages. The article also presents a new way of the upper lateral teeth moving in case of the destroyed crown of the second upper molar which can be carried out by means of stainless steel crowns, orthodontic buttons and mini-implant.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):212-216
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KERATOTOPOGRAPHY IN PATIENTS WITH PSEUDOEXFOLIATIVE SYNDROME AFTER PHACOEMULSIFICATION
EROSHEVSKAYA E.B., GORBUNOV A.E., MALOV V.M., MALOV I.V.
Abstract
The article presents the results of a comparative analysis of keratotopography pattern of induced postoperative astigmatism in patients undergone phacoemulsification via corneal corneoscleral access.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):217-219
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LAZER COAGULATE INTENSITY ANALYSIS IN LASER TREATMENT OF DIABETIC MACULAR EDEMA
ZAMYTSKIJ E.A.
Abstract
The article analyzes the impact of the retinal thickness on the coagulate intensity produced by laser treatment of diabetic macular edema. With the increase of retinal thickness the intensity of laser coagulate applied with a similar power decreases. The article explains the influence of quality of treatment especially by means of subthreshold techniques of laser treatment.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):220-222
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THE USE OF CLASP PROSTHESES WITH LOCK FIXATION SYSTEM IN THE TREATMENT OF PATIENTS WITH PARTIAL ABSENCE OF TEETH (LITERATURE REVIEW)
KOMLEV S.S.
Abstract
The article is devoted to the overview of using clasp prostheses with lock fixation system involving material in the treatment of patients with partial absence of teeth. Contemporary classifications of locking fasteners are presented. The analysis of the choice of locking fasteners in clasp prosthesis construction planning is given in the article.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):223-229
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DIAGNOSIS OF TEMPOROMANDIBULAR ARTHROSIS BASED ON THE NEW WAY OF CT SCANS ANALYSIS
MALTCEVA A.V.
Abstract
The aim of the research was to scrutinize the morphological changes in TMJ tissues and the width of Х-ray joint cavity in different parts of patients with arthrosis. It is performed by the analysis of CT scans of TMJ in 3 projections: sagittal, coronary and axial. We analyzed 36 CT scans of patients with temporomandibular arthrosis, that showed interconnection between symptoms of arthrosis, morphological changes in joint’s elements and constriction of joint cavity in different parts.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):230-233
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MORPHOLOGICAL AND FUNCTIONAL ASPECTS OF ACCOMMODATIVE EYE HYDRODYNAMICS REGULATION (LITERATURE REVIEW)
SIMONYAN I.A.
Abstract
The study of the relationship of accommodation and hydrodynamics points to an important role of these processes in the development of primary open-angle glaucoma. Glaucoma is a disease that leads to severe irreversible changes in the organ of vision and ranks first among the causes of irreversible blindness. Many studies draw attention to the non-randomness of temporal interconnectedness of the occurrence of presbyopia and primary open-angle glaucoma, which makes this problem interesting not only for theoreticians, but also for clinicians, awaiting the opening of additional methods of pathogenetic therapy of open-angle glaucoma.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):234-238
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DEVELOPMENT OF APPROACHES TO THE STANDARDIZATION OF THE RHIZOMES AND ROOTS OF Urtica dioica L
BALAGOZYAN E.A., KURKIN V.A., PRAVDIVCEVA O.E., RIZHOV V.M.
Abstract
The article is devoted to the study of new approaches to the standardization of new medicinal raw materials - rhizomes and roots of nettle (Urticadioica L.). The rhizomes and roots of nettle are the perspective source of drugs for the treatment against prostatic adenoma. A necessary condition for the production of drugs is the development of techniques for the standardization of rhizomes and roots of nettle. In our opinion, the most effective approach to the standardization rhizomes and roots of stinging nettle is the determination of sterol compounds.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):239-241
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INVESTIGATION OF THE PHARMACY ASSORTMENT STRUCTURE OF IRON CONTAINING MEDICINAL PREPARATIONS IN THE STAVROPOL REGION
DIMIDOVA M.A.
Abstract
The purpose of the research is to carry out the study of pharmaceutical assortment of medicines of iron and to propose the strategy for pharmaceutical organizations to optimize the assortment of the given pharmacotherapeutic groups.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):242-244
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ANALYSIS OF HOSPITAL PURCHASE OF MEDICAL AGENTS ON THE PHARMACEUTICAL MARKET OF THE VOLGA FEDERAL DISTRICT
PETRUKHINA I.K., LOGINOVA L.V., YAGUDINA R.I., KURKIN V.A.
Abstract
This article presents an analysis of hospital purchase of drugs on the pharmaceutical market of the Volga Federal District. It was found that hospital purchase accounting for 14 % of all on the pharmaceutical market in the Volga Federal District, through 2011 to 2015 its volume increased by 48% in monetary terms. The purchased medical agents of foreign origin are of the maximum rate in monetary terms. Meanwhile the analysis of hospital medical purchase shows domestic medical agents to be more preferable in kind.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):245-249
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PROTEIN FRACTIONAL COMPOSITION AND MOLECULAR FORMS OF MALATE DEHYDROGENASE IN THE PLANT FRUITS OF THE GENUS FILIPENDULA
SAZANOVA K.N., SHARIPOVA S.K.
Abstract
The investigation of protein fractional composition was performed by means of electrophoresis with polyacrylamide gel. Malate dehydrogenase molecular composition of fresh and dried herbal material of meadowsweet in the humid environment was revealed.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):250-253
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HYGIENIC AND PSYCHOPHYSIOLOGICAL JUSTIFICATION OF FIRST-YEAR STUDENTS ADAPTATION TO THE SYSTEM OF HIGHER EDUCATION
ALESHINA Y.A.
Abstract
The article discusses some of the issues that reveal the features of the first-year students’ organisms adaptation to the high school education system. Hardware complex psycho-physiological and psychological methods to study them has been proven. The article studies the results of the experiment, which should become the natural sciences justification of health hygiene and differential treatment in providing psychological and educational assistance to first-year students of secondary and higher levels of professional education.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):254-257
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THE ANALYSIS OF AGE-RELATED DYNAMICS AND THE METHOD OF BODY MASS INDEX INTERPRETATION IN CHILDREN OF SAMARA REGION
GAVRYUSHIN M.Y.
Abstract
The body mass index (BMI) is an indicator of for the assessment of the adequacy of nutrition. Due to the lack of developed regional standards, BMI is rarely used in pediatric practice. Currently there’s a tendency for increasing obesity among children which requires the optimization of the method BMI assessment in children and adolescents. Research findings demonstrate some positive correlation between BMI and the age of children in Samara region (r=0,588; p < 0,001). Comparative analysis of the body mass index of city school-aged children and those of rural areas in Samara region showed the significant differences (p < 0,05) of BMI in 8 - 14 y.o. boys and 9 - 14 y.o. girls. High age variations of the body mass index and its heterogeneneity in the study area, indicate the need to use regional standards of BMI. In this connection the suggested nonparametric statistical method is more preferable for the interpretation of the values of the BMI.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):258-262
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MULTIENVIRONMENTAL EVALUATION OF HARMFUL FACTORS IMPACT ON THE PUBLIC HEALTH OF LARGE INDUSTRIAL CITY
SERGEEV A.K.
Abstract
The article is devoted to the multienvironmental assessment of the impact of harmful factors on the health of large industrial city population. Dynamics of change of pollution level is presented as priority. Pollutants causing hazards to health are identified. It was found that the high anthropogenic load results in a high level of ecologically dependent morbidity in the city of Samara.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):263-265
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WORKERS’ HEALTH: CURRENT ASSESSMENT AND TRENDS
SUSLIN S.A., PAVLOV V.V., NIKOLSKAYA O.G.
Abstract
The article presents literature review of the current medical and social problems concerning the health of working population. Multidimensional approach with regard to mortality, morbidity level and occupational medicine assessment is paid particular attention. Meanwhile the problems of working population health maintenance in regard to their interaction with the medical organizations is limited and requires more extensive study.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):266-271
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SYSTEMIC APPROACH TO THE REGIONAL HEALTH CARE MANAGEMENT, AIMED AT HEALTH CARE EFFECTIVENESS AND QUALITY IMPROVEMENT
SHISHIN G.G.
Abstract
The medical-organizational actions aimed at the improvement of the medical care control system in the region of Russian Federation are presented in the article. The main of them are the management organization of providing medical care, systemic approach to health care management in the region and the assessment of medical care quality.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):272-276
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PSYCHOLOGICAL ASPECTS OF ORGAN DONATION: THE DESCRIPTION OF SOME CLINICAL CASES
KUVSHINOVA N.Y., MOSTOVAYA L.I.
Abstract
The article includes information about the psychological and ethical issues in clinical transplantation. The article justifies the necessity of psychological diagnostics of the donor and recipient in cases where there is a situation to be an organ transplantation from a living donor.
Aspirantskiy Vestnik Povolzhiya. 2016;16(1-2):277-283
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