Vol 12, No 5-6 (2012)

Articles
The use of scintigraphy in patients with vertebrae deformity of osteoporotic genesis
Alekhin E.N., Alekhin A.N.
Abstract
The problems of vertebrae fractures diagnostics of patients with osteoporosis were considered in this article. The possibility of skeleton scintigraphy in the determination of osteosynthetical processes level in patients with vertebrae fractures of osteoporotic genesis has been studied. The diagnostic efficiency of anatomic methods (СT, MRI, roentgenography) is in comparison with vertebrae metabolic changes visualized by using of scintigraphy with osteotropic indicators.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):9-12
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Clinical efficiencyof metotrecsat in combination withsilimar in the treatment of moderate and severe forms of psoriasis
Arnautova M.S., Arnautova M.S.
Abstract
During the open, controlled, parallel-group comparative study we evaluated the feasibility of supplemental silimar drug to treat moderate and severe psoriasis. We surveyed 65 patients: 30 patients in the control group (conventional therapy) and 35 patients in the studied group, to which in addition to conventional treatment (metotreсsat 5 mg every 12 hours 2-3 times a week) we administered the drug silimar at a dose of 0.2 g three times a day 30 minutes before meals for 35 days. The feature of the study is to calculate the quantitative effect of the intervention.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):13-16
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The thyroid glandfunction in patients with ankylosing spondylitis in standard therapy
Akhunova G.R., Akhunova G.R.
Abstract
This article presents the results of the thyroid gland study in patients with ankylosing spondylitis during standard therapy.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):17-20
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Interrelation of individual properties of patients with rheumatoid arthritis and mental disorders
Akhunova R.R., Akhunova R.R.
Abstract
The study showed the high frequency of non - psychotic psychiatric disorders (113 (64.2%)) in patients with rheumatoid arthritis and their relationship with the individual - typological properties of the personality such as sensory, anxiety and introversion (p<0.05).
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):21-25
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Up-to-date state of microcirculatory impairment problem concerning geriatric patients with pathologyof cardiovascular system and gastro-duodenal diseases (literature review)
Berdyashkina S.I., Berdyashkina S.I.
Abstract
In the article the pathogenesis of coronary heart disease, stomach and duodenal ulcers concerning the microcirculatory impairment is considered. The research methods of the microcirculatory impairment are specified at these diseases.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):26-29
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The significance of non-drug therapies in correction of main ultrasound parameters of liquorodynamics in children with cerebral ischemia
Denisova O.I., Denisova O.I.
Abstract
To increase the effectiveness of standard treatment of cerebral ischemia (CI) in children in the neonatal period, the total magnetic therapy and hyperbaric oxygenation were included. The authors' developed methods were confirmed by the RF patents. The dynamics of the main ultrasound parameters reflecting the state of the ventricular system, the structure of brain tissue and its microcirculation was analyzed. The use of non-drug therapies in treatment of cerebral ischemia contributed to the rapid regression of the size of the ventricles of the brain, restoring their shape, reducing the total index of hyperechogenicity.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):30-35
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Cellular component of a system inflammation in patients with moderate and mild stage of chronic obstructive pulmonary disease during of its exacerbation
Enikeev O.A., Enikeev O.A.
Abstract
In this article we cite data which demonstrate cellular component of a system inflammation in patients with moderate and mild stage of chronic obstructive pulmonary disease (COPD) in dynamics of hospital therapy during the exacerbation of the given disease. 17 patients participated in research with mild and 21 patient with moderate stage of COPD. The control group consists of 20 conditionally healthy persons. The received results demonstrate that COPD exacerbations in patients with moderate and mild stage is characterized by strengthening phagocytic activity against decrease in number of such cells. Also in such patients activation Т and B cells, against the raised level of the T-NK-cells that depict presence of chronic inflammation in patients already with a mild stage is observed. In patients of the moderate stage the exhaustion of NK-cells is observed. It demonstrates the weakness of antiviral and antineoplastic immunity.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):35-40
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The clinical and laboratory characteristic of influenza caused by pandemic strain A H1N1 in pregnant women
Kindalova E.S., Kindalova E.S.
Abstract
Influenza and other acute respiratory viral infections take first place among infectious diseases. The most severe disease was observed in pregnant women dew to changes in immune, respiratory and cardiovascular systems. Pregnant women were hospitalized in the infectious disease clinic where they were examined. Main flu symptoms caused by a pandemic strain A H1N1 virus are fever, intoxication, tracheobronchitis. The average duration of the hectic period consists of 6 ± 1.3 days. The changes in biochemical study were characterized by low levels of blood lactate dehydrogenase (LDH) up to 300 e/l, creatine phosphokinaze (CPK) to 525 e/l. Severe influenza complications as pneumonia were observed in 15 patients (16%). Peculiarities of the severe influenza course is the lack of correlation between the clinical and radiological picture of lung complications, progression of acute respiratory distress syndrome requiring constant respiratory support.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):41-44
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The comparativeanalysis of clinical data in patients with cervicaland essential hypertension and cervical myofascial pain syndrome
Kirsanova A.A., Kirsanova A.A.
Abstract
The same type picture of initial neurophysiological indicators of blink reflex in both studied groups of patients, as well as their unidirectional dynamics as a result of the offered combination therapy in patients with cervical myofascial pain syndrome and cervical and essential hypertension suggests the mechanisms of origin and the maintenance of blood pressure. Registration of the blink reflex dynamics in clinical practice can objectify the severity of comorbidity, and evaluate the effectiveness of treatment and rehabilitation activities. Estimation of parameters of the blink reflex in patients with dysfunction of the cervical spine allows physician to rationally combine manual therapy and acupuncture with drugs.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):45-51
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Features of epilepsy syndrome in children with cerebral cortex malformation
Kuznetsova T.V., Kuznetsova T.V.
Abstract
The epilepsy associated with developted anomalies of the cerebral cortex, makes from 10 % to 25 % from total number of symptomatic epilepsies according. It has the severest course, is often the cause of attacks resistance. Clinico-epidemiological aspects of an epileptic syndrome in children with malformation of cerebral cortex are considered. significant factors of forecast epilepsy course and the influence of MCC on a disease forecast are defined. Main types of epilepsy in children with MCC are pointed out. The algorithm of diagnostics for the purpose of identification of group of risk for the prevention of development of resistant forms of a disease is offered.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):52-56
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The effective treatment of patients with rheumatoid arthritis using high-tone therapy
Kut'ina O.Y., Kutjina O.Y.
Abstract
The work purpose is to show possibilities of complex regenerative treatment of patients with the rheumatoid arthritis, including medicamentous and not medicinal methods: An area inductothermy of adrenal glands, medical massage, physiotherapy exercises, high-tone therapy of area of joints by the technique developed by us (the positive decision on issue of the patent for the invention from 30.05.2012. Application for invention rights № 2011119311/14 (028518). The technique of high-tone therapy developed by us resulted in more expressed medical effect, than other types of pulse currents applied earlier, is well undergone by patients, doesn't cause any side effects. The comprehensive approach gives the chance to minimize aggressive action of medicines on gastroenteric tract and to prolong disease remission. This clinical supervision forces to pay closer attention to studying of possibilities of complex therapy of rheumatoid arthritis and to stimulate development of researches in this direction.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):57-51
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Peculiarities of vascular-thrombocytic and coagulative state of hemostasis system in the geriatric patients undergone myocardial infarction with ischemic heart disease
Pustovalova O.V., Pustovalova O.V.
Abstract
The article dwells on the result of determining the level of prostacyclin in blood plasma, platelet aggregation function and plasma hemostatic factors in the elderly, and centenarians with ischemic heart disease and the patients also underwent myocardial infarction. The decrease of prostacyclin levels in blood plasma, the increase of platelet aggregation and a trend towards an increase of fibrinogen, thrombin time prolongation, and reduced fibrinolytic activity in these patients were revealed.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):62-65
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Up-to-date state of the problem concerning endothelial dysfunction correction in COPD
Selikhova M.A., Kuvaev V.S., Selikhova M.A., Kuvaev V.S.
Abstract
Nowadays endothelial dysfunction is considered as the basis of the pathogenesis of COPD. The paper reviews up-to-date approaches to the treatment of endothelial dysfunction in COPD.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):66-68
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Up-to-dateidea of community-acquired pneumonia (literature review)
Sivakova O.D., Sivakova O.D.
Abstract
Prevalence, aetiology, pharmacoeconomic and pharmacoepidemiology of community-acquired pneumonia in adults are described. Community-acquired pneumonia is one of the most urgent problem of up-to-date medicine. Pneumonia causes huge economic burden. Researches are carried out, which expenses on hospitalization of health care establishments and also expenses connected with disability of the patients are studied. Modern data on pathogenic microorganisms of community-acquired pneumonia and their resistance in different regions of our country and all over the world are provided. Now pharmacoepidemiological researches are carried out in which the application of antibiotics in actual practice is studied. National guidelines and standards are useful for promoting rational treatment.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):69-75
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The spectral opticaltomography study of the layers of the retina in patients with multiple sclerosis
Sineok E.V., Sineok E.V.
Abstract
In our research work the spectral optical tomography Spectralis OCT BluePeak study of the layers of the retina 39 (77 eyes) patients with multiple sclerosis and 12 (24 eyes) comparatively healthy patients with myopic refraction was carried out. For visualization of the fundus it was clearly identified 8 out of 10 layers of the retina. With the help of the developed method the apparent thickness of each layer with an accuracy of ± 5 microns was calculated. It was shown that the patients with multiple sclerosis in addition to general thinning of the first layer of nerve fibers in the retina peripapillary area had statistically significant thinning of the layer of the retina in ganglion layer paramakula area. The average ganglion layer of the retina in the patients with multiple sclerosis ranged 85,75±1,68 µm, whereas in the control group of patients with myopic refraction of the layer thickness varied 97,92±2,26 µm (p<0,01). Layered evaluation of the retina showed characteristic deficits ganglion layer of the retina in patients with multiple sclerosis, which may be a specific marker of multiple sclerosis.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):76-79
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The investigation of the qualityof life of patients with rheumatoid arthritis associated with secondary osteoarthritis according to HAQ
Starodubtseva I.A., Vasil'eva L.V., Starodubtseva I.A., Vasiljeva L.V.
Abstract
The investigation of the quality of life of patients with rheumatoid arthritis associated with secondary osteoarthritis according to HAQ In this trial it was demonstrated the comparison analysis of the quality of life of patients with rheumatoid arthritis in combination with secondary osteoarthritis according to HAQ. It was revealed the relationship between the HAQ and DAS28 (index of activity). It was carried out the evaluation of efficacy of therapy with the use of low level laser irradiation. It the end of the study we concluded that secondary osteoarthritis in patients with rheumatoid arthritis deteriorate the quality of life. Inclusion in complex treatment the laser therapy improves the quality of life and activity of the disease.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):80-83
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The investigation of anti-inflammatory effect mechanism of thioterpenoid of menthanic type
Stepanenko I.S., Akulina I.V., Stepanenko I.S., Akulina I.V.
Abstract
Thioterpenoid 2-(1′-hydroxy-4-isopropenyl-1′-methylcyclohexy-2′-thio)-methylethanoate influence on isoforms of cyclooxygenase activity in rat blood on the model of proliferative inflammation has been studied. It is shown that the studied compound having anti-inflammatory effects has no significant effect on reliable degree of inhibition of cyclooxygenase isoforms.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):84-87
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Peculiarities of fatal outcome of patients with community-acquired pneumonia in the ICU
Chernogaeva G.Y., Chernogaeva G.Y.
Abstract
A comparative analysis of in-hospital mortality of patients with community-acquired pneumonia (CAP) in the ICU unit in 2010 compared with 2000. It was revealed that among the dead in 2010 the average age dropped to 9 years (in 2000 50,1 (± 5,3) years, in 2011 - 41.2 years (± 4,1) - (p <0.05), the prevalence of men increased from 60% to 66%, a later date treatment (13.5% in 2000, 17.3% in 2010) was noted. Among the dead patients in 2010, there were patients with HIV infection (30%), a complication of the pathogenic H1N1 influenza (10%). The number of deaths from tuberculosis consisted of 8.4%.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):88-90
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The condition of the right and left heart in primary and secondary arterial hypertension
Artem'eva I.V., Artemjeva I.V.
Abstract
To study the structural and functional changes of the right and left heart in primary and secondary arterial hypertension (AH). Materials and Methods. The study included 104 patients with various degrees of hypertension (WHO, 1999), including 58 women and 46 men (mean age 52 ± 7,3 years). Surveyed patients were divided into 2 groups: group 1- 70 patients with essential hypertension (EH) I stage (WHO, 1993), group 2 - 34 patients with secondary hypertension syndrome in primary aldosteronism (PA). Common indicators of systolic and diastolic function (DF) of the right ventricle (RV) and left ventricular (LV) were identified during echocardiography (echocardiography) with color Doppler. Results. The process of cardiac remodeling in primary and secondary hypertension has several stages and is characterized by sequential development of structural and functional changes in right and left heart.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):91-96
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Leptin and antiinflammatory factor relationship in patients with myocardial infarction
Belik E.V., Belik E.V.
Abstract
Lack of information about the nature of changes in leptin and its relationship with anti-inflammatory factors in the development of acute coronary events has determined the feasibility of the study. The study included patients with myocardial infarction with and without type 2 diabetes. Identified giperleptinemiya and elevated concentrations of antiinflammatory factors such as CRP and IL-6, as well as their relationship with markers of myocardial necrosis (CK-MB) and leptin can be considered as one of the most important parts of the inflammatory response in myocardial infarction, not only in patients with diabetic history, but also in patients without this comorbidity. The study may form the basis for new diagnostic and therapeutic tactics correction of metabolic abnormalities in patients with acute coronary vascular disease.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):97-101
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The cystatin C value assessment of renal functional condition in patients with chronic heart failure
Berezin I.I., Berezin I.I.
Abstract
The article presents the results of definition of cystatin C at patients with chronic heart failure of ischemic etiology. The article explains its importance in assessing the degree of renal impairment compared with creatinine, GFR, and microalbuminuria. Results: the use of cystatin C can effectively evaluate the presence of renal dysfunction in all groupsof CHF, including subclinical renal dysfunction.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):102-106
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Heart rate and plasma level of natriuretic peptides variability in patients with arterial hypertension and diastolic left ventricular dysfunction
Gubareva I.V., Gubareva I.V.
Abstract
The article dwells on the study of heart rate variability during the day and night in patients with different types of diastolic left ventricular dysfunction. The data correlation analysis of heart rate variability (HRV), echocardiography, markers of diastolic left ventricular dysfunction and natriuretic peptides (NUP) in the studied patients are shown.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):107-112
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Parameters of lipid circulatory system in patients with myocardial infarction and one-, two-, three vascular impairment of coronary bed
Dyleva Y.A., Diljeva Y.A.
Abstract
The steady growth of mortality from MI gives proof of searching of new markers of cardiovascular pathology development. It is known that the key role in the development of atherosclerosis dysfunction is played by oxidatively modified LDL and antibodies to them, generated on the background of oxidative stress. The lack of information about the participation of these markers in the development of myocardial infarction depending on the gravity of the impairment of coronary bed explains the rationale of this study. The patients with myocardial infarction with ST segment elevation with hemodynamically significant stenosis ≥ 75% of one, two, three or more of the coronary arteries were examined. The increase of concentration of oxLDL and antibodies to them on the background of increasing markers of lipid spectrum and indicators pro-/antioxidant systems, continuing and in the subacute period MI, may be a reflection of the gravity of the defeat of coronary bed, in connection with which significantly expand the possibilities of diagnostics of acute as well as recurrent coronary events in patients with myocardial infarction with ST segment elevation in conjunction with multivascular defeat.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):113-120
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Interleukin-1receptor antagonist in hypertensive patients with varying degrees of cardiovascular complications
Kiseleva E.V., Kiseleva E.V.
Abstract
Purpose. The aim of this study was to evaluate the concentration of interleukin-1 receptor antagonist in hypertensive patients with varying degrees of cardiovascular complications. Materials and methods. In 161 patients with I, II grade arterial hypertension aged 35 to 56 years, divided into 3 groups depending on the risk of development of cardiovascular complications were gone examination including echocardiography, ultrasound dopplerography of brachiocephalic vessels , daily blood pressure monitoring, lipid spectrum, glucose level, creatinine level, glomerular filtration rate and IL-1(ra) concentrations in blood serum. Results. In hypertensive patients with moderate cardiovascular risk the severity of inflammatory process depends on the presence of abdominal obesity. In hypertensive patients with high risk of cardiovascular complications direct correlation between IL-1(ra) and intima-media thickening and inverse correlation between IL-1(ra) concentration and GFR was found, it can indicate the association of inflammatory process, renal damage and structural changes of vascular wall which can play a crucial role in pathogenesis of arterial hypertension and development of organ damage.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):121-124
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The surgical reconstruction of left ventricle in patients with coronary heart disease complicated by heart failure
Kuznetsov D.V., Kuznetsov D.V.
Abstract
From 1996 till 2010 in our hospital 136 patients with coronary heart disease complicated by heart failure underwent surgical treatment. The patients were divided into 2 groups: I - the patients with a left ventricular aneurysm (n = 70), II - the patients with ischemic cardiomyopathy (ICMP) (n = 66 patients). All the patients underwent coronary artery bypass surgery, reconstruction of the left ventricle (Dor procedure), the correction of mitral regurgitation. Hospital mortality in group II was 5.4%, all the patients in group I had surgery safely. All the surviving patients after surgery have decreased the size of the left ventricle decreased spherical cavity of the ventricle, increased its fraction. 10 - year survival rate in group I was 78% in the II - 56,5%. Freedom from heart failure of high functional classes (NYHA III, IV), 10 years after surgery the patients in group I was 80.2%, in group II - 68%. The surgical procedure on all components of cardiac pathology in the patients with coronary artery disease and heart failure can achieve satisfactory long-term results.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):125-130
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The variability of heart beat in hypertensive patients with the acute ischemic stroke period
Samol'kina O.G., Samolkina O.G.
Abstract
211 patients aged from 40 to 84 were surveyed. The basic survey sample was 103 hypertensive patients in the acute ischemic stroke period, the control group consisted of 78 hypertensive patients without stroke, the healthy control group included 30 apparently healthy patients. The time indices of Heart Rate Variability were estimated on the evidence of ECG monitoring. The depletion of Heart Rate Variability was diagnosed in the patients of the basic group, maximally - in case of the acute stroke. The degree of Heart Rate Variability depletion correlated with age, severity of stroke, waist circumference, body-weight index, hyperglycemia level.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):131-136
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Endocrine regulation of immune response in children and teenagers with juvenile scleroderma
Antonova Y.Y., Antonova Y.Y.
Abstract
Scleroderma is autoimmune connective tissue pathology in the form of inflammatory changes and sclerosis of the skin or generalized skin lesions and internal organs, accompanied by inflammation and fibrosis of the skin, adipose tissue, mucous membranes and muscles, as well as the development of changes in the gastrointestinal tract, lungs, the heart, kidneys (systemic sclerosis). It has recently proved that the endocrine system participates in the regulation of immune response and the influence of sex hormones on the immune system is intensively studied. The immunity results from the operation of different regulatory systems, among them the leading place is occupied by endocrine one.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):137-142
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Biochemical homeostasis changes while gestational pyelonephritis
Balchenkova Y.P., Balchenkova Y.P.
Abstract
In 145 pregnant women biochemical indicators of liver function while gestational pyelonephritis are studied. It is established that in the first trimester of pregnancy the inflammation of the upper urinary tract helps to reduce the compensatory capacity of the liver and is manifested by the activation of lipid peroxidation, dysproteinemia, a violation of other forms of exchange and the development of endotoxemia.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):143-146
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The comparative description of arterial hypertensionin the Far North children with obesityand metabolic syndrome
Vernigorova N.V., Vernigorova N.V.
Abstract
The complete examination of 109 children and adolescents determines disregulations of daily blood pressure profile not only in metabolic syndrome group, but also in a group of patients with constitutional obesity. However, the most significant and sustained violations are diagnosed in the metabolic syndrome group. Climatic conditions in the northern territories contribute to more early development, rapid progression of obesity, with the development of persistent violations of carbohydrate, lipid metabolism and hemodynamics of violations.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):147-151
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The analysis of taking medicine «Magne B6» effect in the course of the pregnancy and fetus state in women with dysmorphism of the connective tissue
Gracheva O.N., Gracheva O.N.
Abstract
The paper presents the investigation results of taking medicine «Magne B6» effect in 500 women with signs of connective tissue dysplasia. Medical history data, the state of somatic profile are investigated, signs of connective tissue dysplasia are assessed according to T.Y. Smolnova, S.N. Budanova et al. The results of the investigation testify that taking medicine magnesium is favourable for the course of the pregnancy and makes the birth of a child be in time, warns an untimely birth, and it used as prevention of a new born child asphyxia and hypotrophy.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):152-155
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Modern programs of screening to prevent spontaneous preterm birth. The possibility of cervical transvaginal sonography assessment in prognosis of a preterm birth
Malanina E.N., Malanina E.N.
Abstract
The paper gives the data available in the literature on modern programs of screening to prevent spontaneous preterm birth. This study focuses on the clinical value of cervical transvaginal sonography in order to set up groups at risk for the development of preterm birth.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):156-161
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Internal bronchial ozone and laser therapy in children with chronic bronchitis
Mukhamadieva L.A., Mukhamadieva L.A.
Abstract
Undergone ozone and laser therapy 42 children with chronic bronchitis were examined. The children were divided into 4 groups: the first group was a control one, the second group consisted of the patients undergone laser therapy, the third group included the children undergone ozone therapy, the fourth group consisted of the patients undergone combined ozone and laser therapy. The best effect was noted in the group of combined use of ozone and laser therapy, in which after the treatment the indexes of bronchoalveolar lavage fluid were improved, the level of catalase was increased, succinate dehydrogenase, the amount of dien conjugate and malone dialdehyde was decreased.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):162-166
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The influenceof concomitant infections on complication frequency in AIDS-infected pregnant women who lived in the countryside
Rudenko Y.A., Rudenko Y.A.
Abstract
This article deals with the data of AIDS-infected women pregnancy complications frequency, living in the countryside (by example the Kinel District of the Samara Region). It is shown, that AIDS-infection of the third stage aggravates the course of pregnancy only in combination with another virus infections.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):167-169
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Peculiarities of serological indicators (specific Ag A and Ig G to gliadine and antibodies to tissue transglutaminase) in children with celiac
Trifonova E.A., Triphonova E.A.
Abstract
The article presents the research results of serological indicators in 108 children ranging in age from 5 months to 18 years with celiac disease who are examined and treated in the gastroenterology department of N.N. Ivanova ММBI city clinical hospital №1. Antibodies to gliadine (AG) class Ig A, Ig G and antibodies to tissue transglutaminase (ATTT) are taken into account as serological markers. The increase of the AGA than АТТT is more often revealed in the examined patients. In most cases, the increased AG class IgG and most of these changes are recorded in the second group of the children. The increase of antibodies to gliadine is more frequently registered in typical celiac. In the patients with atypical form the increase as AG, so АТТT is revealed. In the children with a latent form, we identify only the increase of the AG class IgG. In the patients ranging in age from 6 to 12 month with the manifestation of celiac the increase of AG and АТТT are more often registered than in other age periods. In the early manifestations of celiac (up to 6 months) the increase of AG is only noted, АТТT remains within the age limit, which may be due to violation of the production in the children of this age.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):170-172
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Life quality of patientswith C5-C6 clinical classes of chronicvenous insufficiency of lowextremities before and afterthe surgical treatment
Zhukov A.A., Zhukov A.A.
Abstract
Life quality of 160 patients with C5-C6 clinical classes of chronic venous insufficiency of low extremities is studied. Life quality index can help to objectification and numerical expression of treatment effectiveness of patients with C5-C6 classes. The main reasons of life quality deterioration of patients with complicated forms of chronic venous insufficiency, in spite of complex treatment, are the symptoms of concomitant pathology of musculo-sceletal system.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):173-176
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Our treatment technique of patients with chondroma of long bones
Ivanov V.V., Terskov A.Y., Nikolaenko A.N., Ivanov V.V., Terskov A.Y., Nikolaenko A.N.
Abstract
In the article the experience of the plasma destruction of bone tissue processing zone resection in surgical treatment of patients with chondroma of long bones is presented. The observation group included 45 patients who underwent surgery at the chondro long bones of different locations. The estimation performance of the role of osteosynthesis for the early activation and prevention of pathological fractures is shown.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):177-181
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Up-to-date approaches to anesthesia during the mini cholecystectomy access
Ivanova I.V., Ivanova I.V.
Abstract
The advantages of the type of anesthesia during the mini cholecystectomy access with the help of the comparative analysis of the impact of different types of anesthesia in the patients with underlying medical conditions were presented. The criteria of anesthesia choice, depending on the source physical status of the patient were offered. 120 patients with different concomitant diseases, aged 25 to 75 years (mean age 41,84 ± 1,01 years) who underwent cholecystectomy from mini to routinely access: under combined anesthesia by inhalation anesthetics (60 patients) and total intravenous anesthesia with mechanical ventilation (60 patients) were examined. All the patients during surgery underwent noninvasive monitoring of blood pressure and heart rate, oxygen saturation, blood gases. It was shown that the minimal hemodynamic changes occured during the induction and maintenance of anesthesia based on sevoflurane or isoflurane.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):182-186
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The treatment results of severe complicated traumas of extremities
Korovin O.A., Korovin O.A.
Abstract
The results of the treatment of 130 patients with purulent complications of bone fractures are studied. 80 patients used one-stage active surgical tactics involving a radical treatment of purulent focus, the stabilization of the fracture with external fixation device and closure of the wound defects, all this led to good results in 82,5% of patients.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):187-192
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The choice of surgical treatment of atherosclerotic carotids impairments in patients with high surgical risk
Suslin Y.V., Suslina E.A., Gavrilova T.A., Suslin Y.V., Suslina E.A., Gavrilova T.A.
Abstract
The comparative analysis of the outcome results and follow-ups of treatment of the patients with atherosclerotic carotid stenoses in groups of high surgical risk is carried out. Comparative methods of surgical treatment were carotid angioplasty with stenting (CAS) and carotid endarterectomy (CEE). The patients undergone carotids surgical procedure (during the period of 2007-2010) were included in the research. The obtained treatment results of the carotids stenosis impairments testify to safety and high efficiency carotid angioplasty with stenting.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):193-196
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The treatment results of chest injury, complicated by hemothorax with suppressed haemorrhage managed by active sanitation of pleural cavity
Titov A.N., Titov A.N.
Abstract
After the application of pleural cavity active sanitation on 44 patients ranging in age from 15 to 86 with chest injuries, complicated by hemothorax with suppressed haemorrhage, the analysis has been done. Since 2010 the method of pleural cavity active sanitation through drainage tube, invented by the author (Patent RF method invention application № 2456935, 27.07.2012, Izmaylov E.P. et al.) has been used in conservative treatment. The essence of the method is fractional lavage of pleural cavity with physiological and/or novocaine solution carried out through Bülau drain, followed by broad-spectrum antibiotic done interpleurally. 4-5 days after the injury magnet therapy and/or calcium chloride electrophoresis should be done on the chest on the side of the injury 5 to 7 times. Depending on the type of conservative treatment all patients were divided into 2 groups. The test group consisted of 60 (57,7%) patients who were treated traditionally. 36 (60%) patients with concomitant chest injuries were included in this group. The main treatment group consisted of 44 (42,3%) patients, who had active sanitation of pleural cavity. 15 (34%) patients with concomitant chest injuries were among them. The patient groups were matched by condition, age, concomitant diseases and nature of injuries. 104 patients were with chest injuries, complicated by hemothorax with suppressed haemorrhage, 9 people died (8,6%). Active sanitation of pleural cavity for patients with chest injury, complicated by hemothorax with suppressed haemorrhage, has reduced the number of thoracotomies by 28,6% and the number of deaths by 3,2%.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):197-200
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The way of treatment and the preparation of local burn wounds IIIB-IV stage for autodermoplasty performedby AKTIVTEX BTEM
Filimonov K.A., Philimonov K.A.
Abstract
On having analyzed the literature and having based on the authors' experience, we believe that at the present stage of the preparation of infected burn wounds the autodermoplasty combined chemotherapeutic drugs that enhance the antibacterial activity in the first phase of wound healing - in the process of inflammation should be made. This task was realized by us due to the improvement of the method of preparation of deep burns for autodermoplasty with the offered wound cover "AKTIVTEX BTEM." The combination of these drugs - butola and eucalyptus oil has strong antibacterial, antinecrotic, dehydrating properties, high penetration into the tissue.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):201-207
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The analysis of dental prosthetics possibility providing to elderly persons in the Samara region
Balueva E.S., Balueva E.S.
Abstract
The article presents the dynamics analysis results of the amount of the Samara Region elderly patients in the cities and the villages, who received dental care in the period of 2007/ 2010. It is established that the growth of dental prosthetics is associated with an increase in the number of pensioners who received dentures provided by commercial services, and the share of elderly persons who received dental prosthesis provided by the budget has diminished steadily.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):208-210
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The mathematicalstudy of the stress-strain stateof the lower jaw with a unilateraldefect in theremote third molar ocation in a one-sidedlateral load
Bolonkin O.N., Bolonkin O.A.
Abstract
The mathematical study of the stress-strain state of the lower jaw with a unilateral defect in the remote third molar location in a one-sided lateral load is carried out. To analyze the deformations that occur in the lower jaw bone structures under the influence of an external load, used pictures of the displacement of its components in the directions of three mutually perpendicular axes X, Y, Z are used. The decrease in strength properties of the lower jaw and an increase in compliance in a remote 48th tooth location is found.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):211-214
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Social status of patients with enamel erosions induced by gastroesophagial refluxe disease
Daneykina O.A., Daneikina O.A.
Abstract
In the article social status of patients with gastroesophagial refluxe disease, enamel erosions is presented. Quality of live is determined and limited by physical and psychology factors. Social status of patients is a base for dentists' interference in the course of the disease in the acute period, its remission and etc. The goal of stomatological treatment during the program realization of reasonable prices treatment for the poverty and the expensive treatment for the rich people is quality of life parameters dynamic by means of somatic and psychological content increasing.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):215-217
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The clinical effectiveness investigation of a new methodic antibacterial pretreatment of complicated canal perforation of the tooth hard tissue
Romanova T.V., Romanova T.V.
Abstract
In endodontics practice during roots of the teeth perforation treatment the antibacterial pretreatment of a root canal of the tooth and perforation zone is of great significance. The method offered by the author including non-medicamentous and antibacterial pretreatment, which consists of combined exposure to laser and ozone therapy (the application invention rights 2012110642/14(015963) dated March 28, 2012), shows effective clinical results. Obtained data allow us to take into consideration this method as the choice in the treatment of roots of the teeth perforation at out-patient clinical departments.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):218-221
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Kagocel and famvir treatment in herpes simplex therapy
Spiridonova S.A., Tolmacheva S.M., Spiridonova S.A., Tolmacheva S.M.
Abstract
Kagocel is shown to be safe and highly clinically effective in treating the patients with recurrent herpes simplex. The drug has antiviral and immunomodulating effects, it is combined with essential formulations, well tolerated, and highly effective in the local and systemic application as monotherapy and in combination with antiviral medicine famvir, by potentiating and prolonging the therapeutic effect.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):222-224
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Biocompatibility estimation of composites based on methacrylate and oxirane in modeling in vitro experiments with saliva
Filippova M.D., Philippova M.D.
Abstract
Nowadays the most important group of dental materials is resin-based сomposites. But composite resin monomers are also applied in many nondental areas. An exposure originating from such nondental applications may cause sensitization. Standard researches of physical, chemical and mechanical properties of biomaterials, and also nonspecific in vitro tests of manufacture are insufficient for an estimation of potential risk material - caused adverse reactions. Necessity of biological researches using new in vitro models with better simulations of the in vivo situation is obvious. We investigated the influence of two dental materials with basically different structures of monomer on activity of enzymes and physical and chemical parameters of saliva.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):225-227
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Stomatological rehabilitation using dental implants in bone tissue atrophy
Shcherchkov S.V., Osman B.M., Braylovskaya T.V., Scherchkov S.V., Osman B.M., Braylovskaya T.V.
Abstract
The question concerns the effectiveness of dental implants in bone tissue deficit. Based on the clinical analysis of 20 patients parallel-resonant frequency indicators for analyzing the stability of intraosseous dental implants were revealed in the following groups: the installation of implants with bone grafting to increase the alveolar crest and horizontal one when using the method of splitting the alveolar ridge.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):228-231
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Innovative approaches to health care pedagogicaltechnology concerningthe health of college students
Abbyasov I.K., Bibarsova G.I., Abbyasov I.K., Bibarsova G.I.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):232-235
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The problem of the choice and grounds of evaluation indicators of budget medical institution activity
Arkhipova S.V., Arkhipova S.V.
Abstract
The article is devoted to the urgent problems of medical organization evaluation. The review of existing approaches to the formation of indicators and their use for the medical organization evaluation. The basic problems of the indicators choice are identified.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):236-239
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The optimization of the realization strategy of data system in a medical institution
Konstantinov D.Y., Chebykin A.V., Konstantinov D.Y., Chebykin A.V.
Abstract
The Ministry of Health Care and Social Development performed the research which showed that the major part of computers was used for the arrangement of the administrative activity in medical institutions while less than 20% of computers were used for diagnostic and treatment procedures. Only 7.7% of medical institutions provide an electronic patient record. At the same time we showed that implementation of personal electronic patient records resulted in medical supply improving, providing of on-time medical aid and control of its quality.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):240-242
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Quality hygienic aspects of water supply and population health protection (literature review)
Mustafina G.I., Mustaphina G.I.
Abstract
In the article the analysis of domestic and foreign scientific literature on a problem of safe and good-quality water supply, for the purpose of development of the preventive hygienic actions directed on ensuring of sanitary-and-epidemiologic wellbeing, the improvement and the preservation of the population health is presented. In the work the microbiological, sanitary and chemical characteristics and hygienic aspects of quality of the centralized economic and drinking water supply in connection with influence on the population health are presented.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):243-248
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WHO's pilot study for physical development assessment of the pupilsin Samara
Poretskova G.Y., Poretskova G.Y.
Abstract
The physical development is defined as one of the fundamental criteria in a complex assessment of a child health state, and its deviation is often the first, clinically revealed symptom of a chronic disease. The assessment of physical development of 343 pupils of average educational institutions of Samara with use of recommended WHO's techniques (Z-score) of Norms of Growth of children is carried out. Some features of their physical development proving need of updating of regional standards of children's growth are revealed.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):249-251
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The organization analysis of the controllable drug groups realization in the Samara region
Savchuk A.Y., Savchuk A.Y.
Abstract
The legislative base analysis, defining sanitary-and-epidemiologic requirements to preservation of the environment and an inhabitancy of the person, the analysis of normative documents under the reference with narcotics and psychotropic substances are lead. The structure of the medical and pharmaceutical organizations participating in drug trafficking and psychotropic substances is studied; the assortment of medical products of controllable groups. The basic infringements of rests destruction process of the medical products in the medical organizations are revealed.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):252-256
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The main directionsof the control improvementof the Russian Federation militaryolder age officershealth
Frank D.L., Frank D.L.
Abstract
The article is devoted to monitoring the health of older age groups officers of the Armed Forces. The urgency of the problem is defined by the armed forces reform, and consequently the changes in the age structure of the officer personnel. The article analyzes the diseases incidence in officers ranging in age from 40 to 45, as well as juridical problems of realization of a military medical examination, as the most important procedures for determining the admission possibility of older age officers groups to further service are investigated.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):257-262
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Urgentquestions on tuberculosis spreading in HIV-patients in Togliatti (Russia, the Samara region)
Tsygankov I.L., Tsygankov I.L.
Abstract
Togliatti is a region with high spreading of HIV infection among the population. It heads the list in the region and it is second in Russia. the situation of HIV spreading and tuberculosis among HIV-infected citizens of Togliatti is studied. The analysis of mortality in comorbidity of HIV / TB is presented. It is revealed that tuberculosis is a major disease and the cause of death among HIV-infected patients. The greatest risk for mortality in the infected HIV patients in 2000/20001, with the decreasing of CD4 - cells less than 200 cells in mсl. (73%) is revealed. The death from TB patients occurs at an average in 3.6 months from the date of tuberculosis manifestation. HAART prescription in these cases is not affected on the unfavorable outcome. HAART taking at an earlier date has reduced the incidence of tuberculosis among HIV-infected patients at 16%.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):263-265
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The organizationof the corporate territorial medical center (based in theNovokuibyshevsk central city hospital)
Sheshunova S.V., Sheshunova S.V.
Abstract
The activity of the corporate territorial medical center located in the Novokuibyshevsk central city hospital of the Samara region is presented as forms of inter-municipal cooperation of medical institutions situated close to each other. The paper shows the economic efficiency, productivity and the population satisfaction of significant medical social work of the corporate Territorial Medical Center.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):266-270
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Social aspects of circulatory system disease incidence
Shuvalova N.V., Shuvalova N.V.
Abstract
Within a high morbidity rate of the blood system diseases in the world the mortality and disability rates are higher in Russia than in the developed countries. 1000 cases were analyzed to define the most significant medical and social risk factors of the blood system diseases for the region.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):271-274
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Artificial gravityis the modulator of the excretoryfunction of the kidneys
Zaytseva E.N., Zajtseva E.N.
Abstract
The first mention of the use of artificial gravity (ICT) on living organisms related to the VIII century. Currently, scientists' interest in the issue is growing. Published data on the effects of ICT on the excretory function of the kidneys are rare unsystematic nature. On the basis of this, it is highly relevant to study the effect on renal excretion IST water, electrolytes and creatinine in the experiment.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):275-278
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The comparative phytochemical study of differentparts of the Rúmex confértus
Zaytseva N.V., Zajtseva N.V.
Abstract
The comparative phytochemical study of different parts of the Rúmex confértus by the method of spectrophotometry was carried out. The amounts of anthracene derivatives and flavonoids in the roots, leaves, stems and flowers of the investigated plant were determined. The perspective of the using in medicine on a level with roots of aerial parts of Rumex (leaves, stems and flowers) was grounded on.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):279-281
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The treatment pathomorphism assessment of prostate cancer afterthe hormonal therapy
Poletaeva S.V., Poletaeva S.V.
Abstract
For the purpose of studying treatment effects of neoadjuvant androgen deprivation in prostate cancer, histological material from 130 patients are examined. 30 patients had received hormonal treatment before radical prostatectomy. All patients were undergone TRUS-guided 12-cores biopsy. Histological, computer morphometry, immunohistochemical methods were used. Rate of (+) surgical margin in group with the hormonal treatment was 13%, in the control group - 17%. The response to androgen deprivation was variable, with areas of the cancer appearing unaffected. The important task is to identify the grade of treatment effects, because the therapy depends on it.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):282-287
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The importance for the test clinical practice using hydroxyapatite-coated implant cells
Ponomareva Y.V., Rozenbaum A.Y., Ponomareva Y.V., Rozenbaum A.Y.
Abstract
At the present stage the innovative development demands new informative methods to control devising implantation materials for dentistry, maxillofacial surgery, traumatology, orthopaedics. Pre-clinical investigations are of great importance. The study is devoted to the methods and the results of testing on cytotoxity, biocompatibility and efficiency of hydroxyapatite-coated implant BT-1-00-titanium using cell's technologies.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):288-290
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Foetal communications morphology at Sudden Infant Death Syndrome (SIDS)
Rozumnyy D.V., Pozumny D.V.
Abstract
For the purpose of foetal communications morphology studying in children died from Sudden Infant Death Syndrome (SIDS) the investigation of 35 newborn and infant hearts with SIDS was performed. 38 infant hearts with sudden death caused by gastric aspiration and infection diseases made the control group. Examination of hearts was done in gross with separate weighting and with use of histological methods. Much more late time of foetal communications obliteration (under 8 month of life) in infants with SIDS and also increase in both ventricles weight were revealed. Connected tissue is mainly located in the oval foramen area of interatrial septum. These factors lead to hemodynamic abnormalities and may play an important role in SIDS.
Aspirantskiy Vestnik Povolzhiya. 2012;12(5-6):291-293
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