PECULIARITIES OF CARDIOVASCULAR OUTCOMES IN MALE AND FEMALE PATIENTS AFTER NOVEL CORONAVIRUS INFECTION CAUSED BY SARS-CoV-2


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Currently, the effects of COVID-19 at cardiovascular system condition in young and middle-aged people, depending on gender, are of profound interest. The aim of the study is to evaluate cardiovascular outcomes in male and female patients after COVID-19 infection. Material and methods. 658 patients aged 25-59 years and underwent a preventive medical examination were included in open comparative study. Depending on the presence or absence of COVID-19 history in anamnesis, they were divided into the main group (n=416, median age 40 (33; 47) years) and the comparison group (n=242, median age 41 (34; 47) years). The main group included 361 (86,8%) females and 55 (13,2%) males, the comparison group included 197 (81,4%) females and 45 (18,6%) males (p=0,083). Demographic indicators, risk factors, cardiovascular risk (CVR) were assessed. A year later, the abovementioned indicators, incidence of COVID-19 and new cases of arterial hypertension (AH), coronary artery disease, and diabetes mellitus were re-registered. Results. After previous COVID-19, arterial hypertension was first diagnosed in 8% (p=0,001) of female and 14,6% (p=0,058) of male patients. A higher incidence in females with overweight (78,1%; p=0,001), hyperglycemia (52%; p=0,001) and moderate cardiovascular risk (61,7%; p=0,008) was fixed. The number of females with high (p=0,037) and very high CVR (p=0,037) increased, and the number of females with low CVR decreased (p=0.001). After previous COVID-19, all male smokers quit smoking (p<0.001), while the number of men with overweight (89%; p=0,001) and very high CVR (25,4%; p=0,002) increased. IHD was diagnosed in 2,8% (p=0,082) of females and 7,2% of males (p=0,126), diabetes mellitus in 3,9% (p=0,012) of females and 5,4% of males (p=0,434) within a median of 3 (2; 4) months after suffering from COVID-19. Conclusion. Females aged 25 to 59 years old with moderate CV risk, overweight, smoking, 3 or more cardiovascular disease (CVD) risk factors, and males of similar age with 3 or more CVD risk factors and smoking who have had COVID-19 infection, should cause medical alertness regarding CVD development.

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作者简介

Kirill Glibko

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia; City Clinical Hospital No. 13 of the Department of Healthcare of Moscow

Email: glibkokv@zdrav.mos.ru
assistant at the Department of polyclinic therapy of the Faculty of general medicine; general practitioner 115280, Moscow, 1/1 Velozavodskaya Str

Sergei Arakelov

City Clinical Hospital No. 13 of the Department of Healthcare of Moscow; Peoples' Friendship University of Russia

Dr. med. habil., head of the Department of family medicine with a course of palliative care of the Faculty of continuing medical education 115280, Moscow, 1/1 Velozavodskaya Str

Irina Titova

City Clinical Hospital No. 13 of the Department of Healthcare of Moscow

deputy chief physician of the medical 115280, Moscow, 1/1 Velozavodskaya Str

Diana Kasaeva

City Clinical Hospital No. 13 of the Department of Healthcare of Moscow

head of the polyclinic 115280, Moscow, 1/1 Velozavodskaya Str

Vera Larina

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: larinav@mail.ru
Dr. med. habil., professor, head of the Department of polyclinic therapy of the Faculty of general medicine 117997, Moscow, 1 Ostrovityanova Str

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