Features of myocardial pathology in patients with extra-axial manifestations of ankylosing spondylitis
- Authors: Feyskhanova L.I.1, Abdrakipov R.Z.2, Vivolanets A.A.1, Akhmedieva D.V.1, Abdulganieva D.I.1
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Affiliations:
- Kazan State Medical University of the Ministry of Healthcare of Russia
- Republican Clinical Hospital of the Ministry of Healthcare of the Republic of Tatarstan
- Issue: Vol 8, No 7 (2022)
- Pages: 27-32
- Section: Articles
- URL: https://journals.eco-vector.com/2412-4036/article/view/276987
- DOI: https://doi.org/10.18565/therapy.2022.7.27-32
- ID: 276987
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Abstract
Ankylosing spondylitis (AS) is one of the socially significant diseases, including due to its negative impact on the myocardium. Purpose of the study: to determine the relationship between extra-axial manifestations and cardiac pathology in patients with AS. Material and methods. A total of 153 patients with AS participated in the study. The patients were divided into 2 groups: 1st - with extraaxial manifestations, 78 people; 2nd gr - without them, 75 people. Patients underwent blood tests to determine the levels of CRP, two-dimensional transthoracic echocardiography, vectorcardiography. Results. Results of the 1st group: E/A level of transthoracic flow, P loop area were significantly higher; relative thickness of the left ventricular wall inversely correlated with QRS loop area (r=-0,36, p=0,02); EchoCG and vectorcardiography parameters had no relation with ASDAS-ESR, BASDAI, BASFI indices. Results of the 2nd group: relative wall thickness had a weak direct relationship with ASDAS-ESR index (r=0,29, p=0,03) and an inverse relationship with maximal vector modulus (r=-0,33, p=0,04). Conclusion. Thus, in AS with extra-axial manifestations, there is an increase in atrial electrical activity accompanied by diastolic dysfunction of the right ventricle.
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About the authors
Lucia I. Feyskhanova
Kazan State Medical University of the Ministry of Healthcare of Russia
Email: ljuts@rambler.ru
PhD in Medicine, associate professor of the Department of hospital therapy 420012, Kazan, 49 Butlerova Str
Rifkat Z. Abdrakipov
Republican Clinical Hospital of the Ministry of Healthcare of the Republic of Tatarstan
Email: hosptherapy@mail.ru
rheumatologist, head of the Department of rheumatology 420064 Kazan, 138 Orenburgsky tract
Anastasia A. Vivolanets
Kazan State Medical University of the Ministry of Healthcare of Russia
Email: vivnastia@gmail.com
6th year student of the Faculty of general medicine 420012, Kazan, 49 Butlerova Str
Diana V. Akhmedieva
Kazan State Medical University of the Ministry of Healthcare of Russia
Email: dhimaa@yandex.ru
6th year student of the Faculty of general medicine 420012, Kazan, 49 Butlerova Str
Diana I. Abdulganieva
Kazan State Medical University of the Ministry of Healthcare of Russia
Email: diana_s@mail.ru
Dr. med. habil., professor, head of the Department of hospital therapy 420012, Kazan, 49 Butlerova Str
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