The basis of modern pharmacotherapy of bronchial asthma in adults
- Authors: Zaitsev A.A.1
-
Affiliations:
- N.N. Burdenko Main Military Clinical Hospital
- Issue: No 1 (2017)
- Pages: 54-59
- Section: Articles
- URL: https://journals.eco-vector.com/2412-4036/article/view/277611
- ID: 277611
Cite item
Open Access
Access granted
Abstract
The article deals with the modern treatment of bronchial asthma (BA). In details the main types of asthma pharmacotherapy are presented. The options for the initial therapy of controlling asthma in adults are presented, as well as the principles of a graded approach to pharmacotherapy in patients with asthma are described. The results of clinical studies and meta-analyzes that evaluate the efficacy of combinations of inhaled corticosteroids and long-acting β2-agonists are presented. It is noted that a great advantage of fixed combinations is not only their high effectiveness in achieving control of asthma symptoms, but also a good compliance due to connection of two drugs in the same inhaler.
Keywords
Full Text
About the authors
Andrey A. Zaitsev
N.N. Burdenko Main Military Clinical Hospital
Email: a-zaicev@yandex.ru
MD, Ohief pulmonologist
References
- Global Strategy for Asthma Management and Prevention. Revised 2016. www.ginasthma.com.
- Asthma in America. Доступно на: www.asthmain-america.com
- Asthma insights reality in Europe. Доступно на: www.asthmaineurope.com.
- Global Atlas of Asthma Published by the European Academy of Allergy and Clinical Immunology 2013. Доступно на: http:// www.eaaci.org
- Федеральные клинические рекомендации по диагностике и лечению бронхиальной астмы 2016. Доступно на: www. pulmonology.ru [Federal clinical recommendations on diagnostics and treatment of asthma 2016. Available at: www. pulmonology.ru (in Russ.)]
- Chuchalin A.G., Khaltaev N., Antonov N.S., Galkin D.V., Manakov L.G., Antonini P., Murphy M., Solodovnikov A.G., Bousquet J., Pereira M.H., Demko I.V. Chronic respiratory diseases and risk factors in 12 regions of the Russian Federation. Int. J. COPD. 2014;9:963-74.
- Chapman K., Boulet L., Rea R., Franssen E. Suboptimal asthma control: prevalence, detection and consequences in general practice. Eur. Respir. J. 2008;1(2):320-5.
- Bateman E., Boushey H., Bousquet J., Busse W., Clark T., Pauwels R., Pedersen S.; GOAL Investigators Group. Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma ControL study. Am. J. Respir. Respir. Crit. Care Med. 2004:170:836-44.
- Barnes N., Jacques L., Goldfrad C., Bateman E.D. Initiation of maintenance treatment with salmeterol/fluticasone propionate 50/100 g bd versus fluticasone propionate 100 g bd alone in patients with persistent asthma: Integrated analysis of four randomised trials. Respir. Medicine. 2007;101:2358-65.
- Bateman E., Nelson H., Bousquet J., Kral K., Sutton L., Ortega H., Yancey S. Meta-analysis: Effects of Adding Salmeterol to Inhaled Corticosteroids on Serious Asthma-Related Events Ann. Intern. Med. 2008;149:33-42.
- Чучалин А.Г., Авдеев С.Н., Айсанов З.Р., Архипов В.В., Белевский А.С., Ненашева Н.М. и др. от лица Российского респираторного общества. Согласованные рекомендации по применению антихолинергического препарата длительного действия тиотропия в терапии бронхиальной астмы. Практическая пульмонология. 2015;1:56-61. [Chuchalin A.G., Avdeev S.N., Aisanov Z.R., Arkhipov V.V., Belevsky A.S., Nenasheva N.M. etc. on behalf of the Russian respiratory society. Agreed recommendations for the use of anticholinergic medication long-acting tiotropiya in the treatment of bronchial asthma. Practical pulmonology. 2015;1:56-61 (in Russ.)]
Supplementary files
