REATMENT OF OSTEOARTHRITIS. THE MAIN COMPONENTS OF THERAPEUTIC COMPLEX


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Abstract

In spite of significant achievements in investigation of osteoarthritis (OA) pathogenesis no single drug can provide sufficient effect in this disease. The best result can be achieved only with the therapeutic complex based on nonpharmacological and pharmacological methods. Glucosamin and chondroitin sulfate are effective drugs for systemic OA treatment possessing analgesic properties. They are widely used in clinical practice and are able to improve symptoms of OA and retard its progression. Nonsteroidal anti-inflammatory drugs (NSAID) can provide significant improvement in most cases but often induce gastro-intestinal and cardio-vascular adverse events. Efficacy of treatment can be further improved with focaf NSAID applications, intra-articular injections of glucocorticoids and of hyaluronic acid.

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About the authors

Yury A. OLYUNIN

Email: yuryaolyunm@yandex.ru
MD, chief of Laboratory of standardization of rheumatic diseases therapy, V.A. Nasonova Research Institute of Rheumatology. 115522, Moscow, 34a Kashyrskoe shosse

Nina Yu. NIKISHINA

PhD, junior clinical research associate, Laboratory of standardization of rheumatic diseases therapy, V.A. Nasonova Research Institute of Rheumatology. 115522, Moscow, 34a Kashyrskoe shosse

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