INTERACTION OF ELECTRICAL AND VISCOELASTIC PARAMETERS WITH BIOCHEMISTRY PARAMETERS IN PATIENTS WITH VARIOUS STAGES OF COLORECTAL CANCER


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Abstract

The red blood parameters, electric and viscoelastic characteristics of of red blood cells, their relationship with biochemistry indices in patients with various stages of colorectal cancer were investigated. The functional characteristics of erythrocytes were studied by the method of dielectrophoresis. The amplitude of deformation of red blood cells, summarized viscosity and rigidity were significant to distinguish the different stages of the disease, while the spent therapy also affects the change of polarizability, capacity of membranes and the value of dipole moment. Correlations viscoelastic and electrical parameters of red blood cells with biochemical parameters were revealed.

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About the authors

Margarita Vitalievna Kruchinina

Scientific Research Institute of Therapy and Preventive Medicine

Email: kruchmargo0yandex.ru
MD, Leading Researcher of Laboratory of Gastroenterology 630089, Novosibirsk, 175/1 B. Bogaykova St

Andrey Vladimirovich Starikov

Novosibirsk Regional Oncological Clinic

Head of Outpatient Department 630108, Novosibirsk, 2 Plakhotnogo St

Andrey Aleksandrovich Gromov

Scientific Research Institute of Therapy and Preventive Medicine

PhD, Senior Researcher of the Laboratory of Clinical Biochemical and Hormonal Studies of Therapeutic Diseases 630089, Novosibirsk, 175/1 B. Bogaykova St

Vladimir Mikhailovich Generalov

State Research Center of Virology and Biotechnology "Vector"

Leading Researcher, Department of Biophysics and Ecological Researches 633159, Novosibirsk region, settlement Koltsovo

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