Fever of unknown origin - a multidisciplinary problem


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Abstract

The term «Fever of unknown origin» corresponds to a situation in clinical practice in which a long-lasting fever is the leading or the only sign of a disease that remains unrecognized during a routine examination. Difficulties in establishing the correct diagnosis are due to the presence of a large number of diseases occurring with a febrile syndrome, which are combined into four groups: generalized or local infectious and inflammatory processes, malignancy, systemic diseases (connective tissue diffuse diseases, vasculitis), other diseases (pathology of the intestine, endocrine organs, etc.). Such a variety of etiological factors dictates the participation in the diagnostic process of representatives of various medical professions - internists, cardiologists, rheumatologists, oncologists and, if necessary, other specialists. A clinical example illustrates the difficulty of diagnosing a disease that occurs with the syndrome of prolonged hyperthermia.

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About the authors

Ivan G. Gordeev

Pirogov Russian National Research Medical University

Email: cardio-150@andex.ru
Doctor of Medicine, professor, Head of the Hospital therapy

Valentina N. Soboleva

Pirogov Russian National Research Medical University of the Ministry of Health care of Russia

Email: vnsoboleva@yandex.ru
MD PhD, Associate Professor of the Department of Hospital Therapy № 1

Nikolai A. Volov

Pirogov Russian National Research Medical University of the Ministry of Health care of Russia

Email: drvolov@yandex.ru
MD PhD, Associate Professor of the Department of Hospital Therapy № 1

Yulia M. Mashukova

Pirogov Russian National Research Medical University of the Ministry of Health care of Russia

Email: alfilenko@rambler.ru
MD PhD, Associate Professor of the Department of Hospital Therapy № 1

Elena E. Luchinkina

Pirogov Russian National Research Medical University of the Ministry of Health care of Russia

Email: eluchinkina@gmail.com
MD PhD, Associate Professor of the Department of Hospital Therapy № 1

Sevinch S. Mamedguseyinova

Pirogov Russian National Research Medical University of the Ministry of Health care of Russia

Email: audilovett@mail.ru
Laboratory assistant of the Department of Hospital Therapy No. 1

Nina D. Lapochkina

Pirogov Russian National Research Medical University of the Ministry of Health care of Russia

Email: n_lapochkina@bk.ru
Laboratory assistant of the Department of Hospital Therapy No. 1

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