Disturbances of water and electrolyte homeostasis as a predictor of an unfavorable long-term prognosis in patients hospitalized for decompensated CHF


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Abstract

Objectives: to investigate correlation between electrolyte imbalance at admission and long-term prognosis. Material and methods: the research based on the data of physical examination, laboratory and instrumental investigation of 111 consecutive patients hospitalized for decompensated heart failure (HF), III-IV functional class NYHA. Results: Mean age 71±12 years; 44,1% were males; 64,0% had emergency admission (IV functional class NYHA), mean left ventricular ejection fraction 41±15%. Electrolyte imbalance at admission was presented in 33,3% of patients. Multivariable survival analysis revealed 2,33-fold independently increased relative risk of all-cause mortality for the patients with electrolyte imbalance at admission [HR 2,33; 95% CI 1,19-7,70; p=0,0201]. Conclusion: in patients hospitalized for decompensated HF, electrolyte imbalance at admission is a predictor of unfavorable prognosis and increased a year mortality.

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About the authors

Christina S. Fazulina

Federal State Autonomous Educational Institution of Higher Education I. M. Sechenov «First Moscow State Medical University Under the Ministry of Health of the Russian Federation» (Sechenov University)

Email: kristy874@yandex.ru
M.D., сardiologist, applicant of internal medicine №1

Victor V. Fomin

Federal State Autonomous Educational Institution of Higher Education I. M. Sechenov «First Moscow State Medical University Under the Ministry of Health of the Russian Federation» (Sechenov University)

Email: fomin@mma.ru
M.D., Ph.D, professor, corresponding member of the Russian Academy of Science, Vice-Rector for Research and Health-care, chair of internal medicine №1

Victoria V. Meshalkina

Municipal clinical hospital № 24 of Departament of Health care of Moscow

Email: v.meshalkina2017@yandex.ru
M.D., сardiologist

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